data_IBI
#

_chem_comp.id                                   IBI
_chem_comp.name                                 "N-{trans-4-[4-(cyclopropylmethyl)piperazin-1-yl]cyclohexyl}-4-{[(7R)-7-ethyl-5-methyl-8-(1-methylethyl)-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxybenzamide"
_chem_comp.type                                 NON-POLYMER
_chem_comp.pdbx_type                            HETAIN
_chem_comp.formula                              "C34 H50 N8 O3"
_chem_comp.mon_nstd_parent_comp_id              ?
_chem_comp.pdbx_synonyms                        Volasertib
_chem_comp.pdbx_formal_charge                   0
_chem_comp.pdbx_initial_date                    2008-11-25
_chem_comp.pdbx_modified_date                   2021-03-01
_chem_comp.pdbx_ambiguous_flag                  N
_chem_comp.pdbx_release_status                  REL
_chem_comp.pdbx_replaced_by                     ?
_chem_comp.pdbx_replaces                        ?
_chem_comp.formula_weight                       618.813
_chem_comp.one_letter_code                      ?
_chem_comp.three_letter_code                    IBI
_chem_comp.pdbx_model_coordinates_details       ?
_chem_comp.pdbx_model_coordinates_missing_flag  N
_chem_comp.pdbx_ideal_coordinates_details       Corina
_chem_comp.pdbx_ideal_coordinates_missing_flag  N
_chem_comp.pdbx_model_coordinates_db_code       3FC2
_chem_comp.pdbx_subcomponent_list               ?
_chem_comp.pdbx_processing_site                 PDBJ
#   #
loop_
_chem_comp_atom.comp_id
_chem_comp_atom.atom_id
_chem_comp_atom.alt_atom_id
_chem_comp_atom.type_symbol
_chem_comp_atom.charge
_chem_comp_atom.pdbx_align
_chem_comp_atom.pdbx_aromatic_flag
_chem_comp_atom.pdbx_leaving_atom_flag
_chem_comp_atom.pdbx_stereo_config
_chem_comp_atom.model_Cartn_x
_chem_comp_atom.model_Cartn_y
_chem_comp_atom.model_Cartn_z
_chem_comp_atom.pdbx_model_Cartn_x_ideal
_chem_comp_atom.pdbx_model_Cartn_y_ideal
_chem_comp_atom.pdbx_model_Cartn_z_ideal
_chem_comp_atom.pdbx_component_atom_id
_chem_comp_atom.pdbx_component_comp_id
_chem_comp_atom.pdbx_ordinal
IBI  C1    C1    C  0  1  N  N  N  51.334   -0.914   9.563   -8.109   2.109  -0.788  C1    IBI   1  
IBI  C2    C2    C  0  1  N  N  N  52.240    0.295   9.236   -9.623   2.307  -0.689  C2    IBI   2  
IBI  C5    C5    C  0  1  N  N  N  53.176   -2.035  10.617   -8.249   0.257   0.764  C5    IBI   3  
IBI  C6    C6    C  0  1  N  N  N  54.106   -0.836  10.310   -9.763   0.455   0.863  C6    IBI   4  
IBI  C7    C7    C  0  1  N  N  N  49.304   -4.803   8.651   -4.126   0.804   1.786  C7    IBI   5  
IBI  C8    C8    C  0  1  N  N  N  50.026   -3.445   8.830   -5.649   0.944   1.815  C8    IBI   6  
IBI  C11   C11   C  0  1  N  N  N  51.323   -6.023   9.235   -4.223   0.249  -0.648  C11   IBI   7  
IBI  C12   C12   C  0  1  N  N  N  52.133   -4.706   9.400   -5.747   0.389  -0.619  C12   IBI   8  
IBI  C15   C15   C  0  1  Y  N  N  47.231   -9.355   7.919    0.571  -0.575   0.655  C15   IBI   9  
IBI  C16   C16   C  0  1  Y  N  N  47.687  -11.432   6.153    1.724  -2.930  -0.275  C16   IBI  10  
IBI  C17   C17   C  0  1  Y  N  N  48.274   -9.229   6.984   -0.236  -1.627   0.216  C17   IBI  11  
IBI  C18   C18   C  0  1  Y  N  N  48.480  -10.281   6.099    0.350  -2.808  -0.251  C18   IBI  12  
IBI  C21   C21   C  0  1  N  N  R  42.442  -12.970  12.185    8.911   0.819  -0.934  C21   IBI  13  
IBI  N22   N22   N  0  1  N  N  N  42.124  -14.897  10.601    7.035   2.407  -0.704  N22   IBI  14  
IBI  C24   C24   C  0  1  Y  N  N  43.122  -14.345   9.730    6.225   1.286  -0.473  C24   IBI  15  
IBI  C31   C31   C  0  1  N  N  N  43.306  -13.493  13.375   10.392   0.836  -0.552  C31   IBI  16  
IBI  C32   C32   C  0  1  N  N  N  44.582  -14.273  12.959   10.971  -0.573  -0.691  C32   IBI  17  
IBI  C33   C33   C  0  1  N  N  N  43.963  -11.127  11.792    8.586   0.197   1.380  C33   IBI  18  
IBI  C34   C34   C  0  1  N  N  N  45.372  -10.825  11.299    8.052   1.558   1.830  C34   IBI  19  
IBI  C35   C35   C  0  1  N  N  N  43.043   -9.893  11.682    8.015  -0.899   2.283  C35   IBI  20  
IBI  C36   C36   C  0  1  N  N  N  41.442  -16.175  10.294    6.453   3.751  -0.764  C36   IBI  21  
IBI  C38   C38   C  0  1  N  N  N  49.096  -12.817   4.680    1.416  -5.115  -1.162  C38   IBI  22  
IBI  C39   C39   C  0  1  N  N  N  49.159   -7.989   6.935   -1.706  -1.492   0.244  C39   IBI  23  
IBI  O40   O40   O  0  1  N  N  N  49.665   -7.703   5.887   -2.408  -2.408  -0.139  O40   IBI  24  
IBI  O37   O37   O  0  1  N  N  N  47.862  -12.498   5.305    2.297  -4.077  -0.727  O37   IBI  25  
IBI  C14   C14   C  0  1  Y  N  N  46.652  -11.544   7.078    2.526  -1.875   0.166  C14   IBI  26  
IBI  N19   N19   N  0  1  N  N  N  45.958  -12.792   7.055    3.915  -1.999   0.141  N19   IBI  27  
IBI  C26   C26   C  0  1  Y  N  N  45.019  -13.331   7.974    4.707  -0.879  -0.062  C26   IBI  28  
IBI  N27   N27   N  0  1  Y  N  N  44.688  -12.651   9.133    6.024  -0.998   0.035  N27   IBI  29  
IBI  C25   C25   C  0  1  Y  N  N  43.744  -13.126  10.022    6.810   0.056  -0.154  C25   IBI  30  
IBI  N23   N23   N  0  1  N  N  N  43.395  -12.396  11.213    8.182  -0.054  -0.009  N23   IBI  31  
IBI  N28   N28   N  0  1  Y  N  N  44.408  -14.528   7.692    4.126   0.276  -0.346  N28   IBI  32  
IBI  C29   C29   C  0  1  Y  N  N  43.468  -15.022   8.570    4.847   1.370  -0.557  C29   IBI  33  
IBI  C20   C20   C  0  1  N  N  N  41.755  -14.236  11.770    8.363   2.221  -0.871  C20   IBI  34  
IBI  O30   O30   O  0  1  N  N  N  40.928  -14.691  12.539    9.107   3.174  -0.967  O30   IBI  35  
IBI  C13   C13   C  0  1  Y  N  N  46.427  -10.498   7.966    1.943  -0.702   0.629  C13   IBI  36  
IBI  N41   N41   N  0  1  N  N  N  49.411   -7.188   8.060   -2.269  -0.354   0.694  N41   IBI  37  
IBI  C9    C9    C  0  1  N  N  N  50.219   -5.932   8.179   -3.728  -0.220   0.722  C9    IBI  38  
IBI  C10   C10   C  0  1  N  N  N  51.285   -3.452   9.748   -6.145   1.413   0.446  C10   IBI  39  
IBI  N3    N3    N  0  1  N  N  N  52.103   -2.195   9.591   -7.607   1.547   0.474  N3    IBI  40  
IBI  N4    N4    N  0  1  N  N  N  53.361    0.436  10.191  -10.265   1.017  -0.399  N4    IBI  41  
IBI  C42   C42   C  0  1  N  N  N  54.247    1.572   9.880  -11.727   1.151  -0.371  C42   IBI  42  
IBI  C43   C43   C  0  1  N  N  N  53.804    2.914  10.499  -12.366  -0.238  -0.316  C43   IBI  43  
IBI  C45   C45   C  0  1  N  N  N  54.086    4.297   9.952  -13.887  -0.311  -0.162  C45   IBI  44  
IBI  C44   C44   C  0  1  N  N  N  52.732    3.713   9.713  -13.235  -0.664  -1.501  C44   IBI  45  
IBI  H1    H1    H  0  1  N  N  N  50.878   -0.755  10.551   -7.884   1.424  -1.606  H1    IBI  46  
IBI  H1A   H1A   H  0  1  N  N  N  50.569   -0.991   8.776   -7.628   3.069  -0.975  H1A   IBI  47  
IBI  H2    H2    H  0  1  N  N  N  52.656    0.156   8.227   -9.847   3.012   0.111  H2    IBI  48  
IBI  H2A   H2A   H  0  1  N  N  N  51.625    1.204   9.303  -10.002   2.696  -1.634  H2A   IBI  49  
IBI  H5    H5    H  0  1  N  N  N  53.782   -2.953  10.636   -7.871  -0.133   1.709  H5    IBI  50  
IBI  H5A   H5A   H  0  1  N  N  N  52.692   -1.849  11.587   -8.026  -0.448  -0.036  H5A   IBI  51  
IBI  H6    H6    H  0  1  N  N  N  54.834   -0.740  11.129  -10.244  -0.506   1.050  H6    IBI  52  
IBI  H6A   H6A   H  0  1  N  N  N  54.600   -1.030   9.347   -9.988   1.139   1.681  H6A   IBI  53  
IBI  H7    H7    H  0  1  N  N  N  48.879   -5.093   9.623   -3.677   1.768   1.548  H7    IBI  54  
IBI  H7A   H7A   H  0  1  N  N  N  48.539   -4.661   7.873   -3.773   0.470   2.762  H7A   IBI  55  
IBI  H8    H8    H  0  1  N  N  N  50.350   -3.113   7.833   -6.098  -0.021   2.053  H8    IBI  56  
IBI  H8A   H8A   H  0  1  N  N  N  49.300   -2.783   9.324   -5.933   1.673   2.574  H8A   IBI  57  
IBI  H11   H11   H  0  1  N  N  N  52.020   -6.819   8.934   -3.940  -0.481  -1.406  H11   IBI  58  
IBI  H11A  H11A  H  0  0  N  N  N  50.835   -6.229  10.199   -3.775   1.213  -0.886  H11A  IBI  59  
IBI  H12   H12   H  0  1  N  N  N  52.854   -4.858  10.216   -6.100   0.723  -1.594  H12   IBI  60  
IBI  H12A  H12A  H  0  0  N  N  N  52.599   -4.504   8.424   -6.195  -0.576  -0.381  H12A  IBI  61  
IBI  H15   H15   H  0  1  N  N  N  47.047   -8.551   8.616    0.120   0.339   1.012  H15   IBI  62  
IBI  H18   H18   H  0  1  N  N  N  49.263  -10.209   5.359   -0.272  -3.623  -0.591  H18   IBI  63  
IBI  H21   H21   H  0  1  N  N  N  41.700  -12.177  12.358    8.804   0.438  -1.950  H21   IBI  64  
IBI  H31   H31   H  0  1  N  N  N  43.624  -12.622  13.967   10.930   1.516  -1.213  H31   IBI  65  
IBI  H31A  H31A  H  0  0  N  N  N  42.675  -14.200  13.933   10.498   1.173   0.479  H31A  IBI  66  
IBI  H32   H32   H  0  1  N  N  N  44.562  -14.458  11.875   12.002  -0.579  -0.336  H32   IBI  67  
IBI  H32A  H32A  H  0  0  N  N  N  45.473  -13.681  13.214   10.379  -1.269  -0.097  H32A  IBI  68  
IBI  H32B  H32B  H  0  0  N  N  N  44.615  -15.234  13.494   10.945  -0.876  -1.738  H32B  IBI  69  
IBI  H33   H33   H  0  1  N  N  N  44.030  -11.342  12.869    9.674   0.193   1.448  H33   IBI  70  
IBI  H34   H34   H  0  1  N  N  N  45.369  -10.752  10.201    8.352   1.744   2.861  H34   IBI  71  
IBI  H34A  H34A  H  0  0  N  N  N  45.714   -9.872  11.729    8.458   2.339   1.187  H34A  IBI  72  
IBI  H34B  H34B  H  0  0  N  N  N  46.050  -11.633  11.611    6.964   1.561   1.762  H34B  IBI  73  
IBI  H35   H35   H  0  1  N  N  N  42.824   -9.507  12.689    6.932  -0.933   2.171  H35   IBI  74  
IBI  H35A  H35A  H  0  0  N  N  N  43.546   -9.113  11.092    8.441  -1.861   2.000  H35A  IBI  75  
IBI  H35B  H35B  H  0  0  N  N  N  42.103  -10.180  11.187    8.267  -0.682   3.321  H35B  IBI  76  
IBI  H36   H36   H  0  1  N  N  N  41.273  -16.250   9.210    6.451   4.190   0.233  H36   IBI  77  
IBI  H36A  H36A  H  0  0  N  N  N  42.070  -17.015  10.626    7.046   4.373  -1.435  H36A  IBI  78  
IBI  H36B  H36B  H  0  0  N  N  N  40.476  -16.210  10.819    5.431   3.688  -1.136  H36B  IBI  79  
IBI  H38   H38   H  0  1  N  N  N  48.947  -12.900   3.593    2.001  -5.972  -1.497  H38   IBI  80  
IBI  H38A  H38A  H  0  0  N  N  N  49.829  -12.024   4.890    0.773  -5.415  -0.335  H38A  IBI  81  
IBI  H38B  H38B  H  0  0  N  N  N  49.469  -13.775   5.072    0.803  -4.749  -1.986  H38B  IBI  82  
IBI  HN19  HN19  H  0  0  N  N  N  46.165  -13.377   6.271    4.326  -2.869   0.265  HN19  IBI  83  
IBI  H29   H29   H  0  1  N  N  N  42.987  -15.963   8.349    4.367   2.309  -0.790  H29   IBI  84  
IBI  H13   H13   H  0  1  N  N  N  45.631  -10.568   8.692    2.566   0.112   0.969  H13   IBI  85  
IBI  HN41  HN41  H  0  0  N  N  N  48.988   -7.503   8.909   -1.709   0.377   0.999  HN41  IBI  86  
IBI  H9    H9    H  0  1  N  N  N  50.668   -5.761   7.189   -4.177  -1.185   0.960  H9    IBI  87  
IBI  H10   H10   H  0  1  N  N  N  50.964   -3.487  10.799   -5.696   2.377   0.208  H10   IBI  88  
IBI  H42   H42   H  0  1  N  N  N  55.248    1.335  10.269  -12.023   1.722   0.509  H42   IBI  89  
IBI  H42A  H42A  H  0  0  N  N  N  54.222    1.703   8.788  -12.062   1.669  -1.270  H42A  IBI  90  
IBI  H43   H43   H  0  1  N  N  N  53.975    2.476  11.494  -11.773  -1.009   0.176  H43   IBI  91  
IBI  H45   H45   H  0  1  N  N  N  54.371    5.218  10.482  -14.294  -1.130   0.430  H45   IBI  92  
IBI  H45A  H45A  H  0  0  N  N  N  54.867    4.735   9.312  -14.432   0.630  -0.100  H45A  IBI  93  
IBI  H44   H44   H  0  1  N  N  N  52.198    3.482   8.779  -13.352   0.046  -2.320  H44   IBI  94  
IBI  H44A  H44A  H  0  0  N  N  N  51.691    4.025   9.883  -13.214  -1.715  -1.789  H44A  IBI  95  
#   #
loop_
_chem_comp_bond.comp_id
_chem_comp_bond.atom_id_1
_chem_comp_bond.atom_id_2
_chem_comp_bond.value_order
_chem_comp_bond.pdbx_aromatic_flag
_chem_comp_bond.pdbx_stereo_config
_chem_comp_bond.pdbx_ordinal
IBI  C1   C2    SING  N  N    1  
IBI  C1   N3    SING  N  N    2  
IBI  C2   N4    SING  N  N    3  
IBI  C5   C6    SING  N  N    4  
IBI  C5   N3    SING  N  N    5  
IBI  C6   N4    SING  N  N    6  
IBI  C7   C8    SING  N  N    7  
IBI  C7   C9    SING  N  N    8  
IBI  C8   C10   SING  N  N    9  
IBI  C11  C12   SING  N  N   10  
IBI  C11  C9    SING  N  N   11  
IBI  C12  C10   SING  N  N   12  
IBI  C15  C17   DOUB  Y  N   13  
IBI  C15  C13   SING  Y  N   14  
IBI  C16  C18   DOUB  Y  N   15  
IBI  C16  O37   SING  N  N   16  
IBI  C16  C14   SING  Y  N   17  
IBI  C17  C18   SING  Y  N   18  
IBI  C17  C39   SING  N  N   19  
IBI  C21  C31   SING  N  N   20  
IBI  C21  N23   SING  N  N   21  
IBI  C21  C20   SING  N  N   22  
IBI  N22  C24   SING  N  N   23  
IBI  N22  C36   SING  N  N   24  
IBI  N22  C20   SING  N  N   25  
IBI  C24  C25   DOUB  Y  N   26  
IBI  C24  C29   SING  Y  N   27  
IBI  C31  C32   SING  N  N   28  
IBI  C33  C34   SING  N  N   29  
IBI  C33  C35   SING  N  N   30  
IBI  C33  N23   SING  N  N   31  
IBI  C38  O37   SING  N  N   32  
IBI  C39  O40   DOUB  N  N   33  
IBI  C39  N41   SING  N  N   34  
IBI  C14  N19   SING  N  N   35  
IBI  C14  C13   DOUB  Y  N   36  
IBI  N19  C26   SING  N  N   37  
IBI  C26  N27   DOUB  Y  N   38  
IBI  C26  N28   SING  Y  N   39  
IBI  N27  C25   SING  Y  N   40  
IBI  C25  N23   SING  N  N   41  
IBI  N28  C29   DOUB  Y  N   42  
IBI  C20  O30   DOUB  N  N   43  
IBI  N41  C9    SING  N  N   44  
IBI  C10  N3    SING  N  N   45  
IBI  N4   C42   SING  N  N   46  
IBI  C42  C43   SING  N  N   47  
IBI  C43  C45   SING  N  N   48  
IBI  C43  C44   SING  N  N   49  
IBI  C45  C44   SING  N  N   50  
IBI  C1   H1    SING  N  N   51  
IBI  C1   H1A   SING  N  N   52  
IBI  C2   H2    SING  N  N   53  
IBI  C2   H2A   SING  N  N   54  
IBI  C5   H5    SING  N  N   55  
IBI  C5   H5A   SING  N  N   56  
IBI  C6   H6    SING  N  N   57  
IBI  C6   H6A   SING  N  N   58  
IBI  C7   H7    SING  N  N   59  
IBI  C7   H7A   SING  N  N   60  
IBI  C8   H8    SING  N  N   61  
IBI  C8   H8A   SING  N  N   62  
IBI  C11  H11   SING  N  N   63  
IBI  C11  H11A  SING  N  N   64  
IBI  C12  H12   SING  N  N   65  
IBI  C12  H12A  SING  N  N   66  
IBI  C15  H15   SING  N  N   67  
IBI  C18  H18   SING  N  N   68  
IBI  C21  H21   SING  N  N   69  
IBI  C31  H31   SING  N  N   70  
IBI  C31  H31A  SING  N  N   71  
IBI  C32  H32   SING  N  N   72  
IBI  C32  H32A  SING  N  N   73  
IBI  C32  H32B  SING  N  N   74  
IBI  C33  H33   SING  N  N   75  
IBI  C34  H34   SING  N  N   76  
IBI  C34  H34A  SING  N  N   77  
IBI  C34  H34B  SING  N  N   78  
IBI  C35  H35   SING  N  N   79  
IBI  C35  H35A  SING  N  N   80  
IBI  C35  H35B  SING  N  N   81  
IBI  C36  H36   SING  N  N   82  
IBI  C36  H36A  SING  N  N   83  
IBI  C36  H36B  SING  N  N   84  
IBI  C38  H38   SING  N  N   85  
IBI  C38  H38A  SING  N  N   86  
IBI  C38  H38B  SING  N  N   87  
IBI  N19  HN19  SING  N  N   88  
IBI  C29  H29   SING  N  N   89  
IBI  C13  H13   SING  N  N   90  
IBI  N41  HN41  SING  N  N   91  
IBI  C9   H9    SING  N  N   92  
IBI  C10  H10   SING  N  N   93  
IBI  C42  H42   SING  N  N   94  
IBI  C42  H42A  SING  N  N   95  
IBI  C43  H43   SING  N  N   96  
IBI  C45  H45   SING  N  N   97  
IBI  C45  H45A  SING  N  N   98  
IBI  C44  H44   SING  N  N   99  
IBI  C44  H44A  SING  N  N  100  
#   #
loop_
_pdbx_chem_comp_descriptor.comp_id
_pdbx_chem_comp_descriptor.type
_pdbx_chem_comp_descriptor.program
_pdbx_chem_comp_descriptor.program_version
_pdbx_chem_comp_descriptor.descriptor
IBI  SMILES            ACDLabs               10.04  "O=C6N(c1c(nc(nc1)Nc2ccc(cc2OC)C(=O)NC5CCC(N3CCN(CC3)CC4CC4)CC5)N(C(C)C)C6CC)C"  
IBI  SMILES_CANONICAL  CACTVS                3.341  "CC[C@H]1N(C(C)C)c2nc(Nc3ccc(cc3OC)C(=O)N[C@H]4CC[C@@H](CC4)N5CCN(CC5)CC6CC6)ncc2N(C)C1=O"  
IBI  SMILES            CACTVS                3.341  "CC[CH]1N(C(C)C)c2nc(Nc3ccc(cc3OC)C(=O)N[CH]4CC[CH](CC4)N5CCN(CC5)CC6CC6)ncc2N(C)C1=O"  
IBI  SMILES_CANONICAL  "OpenEye OEToolkits"  1.5.0  "CC[C@@H]1C(=O)N(c2cnc(nc2N1C(C)C)Nc3ccc(cc3OC)C(=O)NC4CCC(CC4)N5CCN(CC5)CC6CC6)C"  
IBI  SMILES            "OpenEye OEToolkits"  1.5.0  "CCC1C(=O)N(c2cnc(nc2N1C(C)C)Nc3ccc(cc3OC)C(=O)NC4CCC(CC4)N5CCN(CC5)CC6CC6)C"  
IBI  InChI             InChI                 1.03   "InChI=1S/C34H50N8O3/c1-6-28-33(44)39(4)29-20-35-34(38-31(29)42(28)22(2)3)37-27-14-9-24(19-30(27)45-5)32(43)36-25-10-12-26(13-11-25)41-17-15-40(16-18-41)21-23-7-8-23/h9,14,19-20,22-23,25-26,28H,6-8,10-13,15-18,21H2,1-5H3,(H,36,43)(H,35,37,38)/t25-,26-,28-/m1/s1"  
IBI  InChIKey          InChI                 1.03   SXNJFOWDRLKDSF-STROYTFGSA-N  
#   #
loop_
_pdbx_chem_comp_identifier.comp_id
_pdbx_chem_comp_identifier.type
_pdbx_chem_comp_identifier.program
_pdbx_chem_comp_identifier.program_version
_pdbx_chem_comp_identifier.identifier
IBI  "SYSTEMATIC NAME"  ACDLabs               10.04  "N-{trans-4-[4-(cyclopropylmethyl)piperazin-1-yl]cyclohexyl}-4-{[(7R)-7-ethyl-5-methyl-8-(1-methylethyl)-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxybenzamide"  
IBI  "SYSTEMATIC NAME"  "OpenEye OEToolkits"  1.5.0  "N-[4-[4-(cyclopropylmethyl)piperazin-1-yl]cyclohexyl]-4-[[(7R)-7-ethyl-5-methyl-6-oxo-8-propan-2-yl-7H-pteridin-2-yl]amino]-3-methoxy-benzamide"  
#   #
loop_
_pdbx_chem_comp_audit.comp_id
_pdbx_chem_comp_audit.action_type
_pdbx_chem_comp_audit.date
_pdbx_chem_comp_audit.processing_site
IBI  "Create component"      2008-11-25  PDBJ  
IBI  "Modify aromatic_flag"  2011-06-04  RCSB  
IBI  "Modify descriptor"     2011-06-04  RCSB  
IBI  "Modify synonyms"       2018-03-29  PDBJ  
IBI  "Modify synonyms"       2021-03-01  PDBE  
#
_pdbx_chem_comp_synonyms.ordinal     1
_pdbx_chem_comp_synonyms.comp_id     IBI
_pdbx_chem_comp_synonyms.name        Volasertib
_pdbx_chem_comp_synonyms.provenance  ?
_pdbx_chem_comp_synonyms.type        ?
##
