data_9EA
# 
_chem_comp.id                                    9EA 
_chem_comp.name                                  "7-(3-{[4-(4-acetylpiperazin-1-yl)phenoxy]methyl}-1,5-dimethyl-1H-pyrazol-4-yl)-3-{3-[(naphthalen-1-yl)oxy]propyl}-1-[(pyridin-3-yl)methyl]-1H-indole-2-carboxylic acid" 
_chem_comp.type                                  NON-POLYMER 
_chem_comp.pdbx_type                             HETAIN 
_chem_comp.formula                               "C46 H46 N6 O5" 
_chem_comp.mon_nstd_parent_comp_id               ? 
_chem_comp.pdbx_synonyms                         ? 
_chem_comp.pdbx_formal_charge                    0 
_chem_comp.pdbx_initial_date                     2017-04-24 
_chem_comp.pdbx_modified_date                    2017-04-28 
_chem_comp.pdbx_ambiguous_flag                   N 
_chem_comp.pdbx_release_status                   REL 
_chem_comp.pdbx_replaced_by                      ? 
_chem_comp.pdbx_replaces                         ? 
_chem_comp.formula_weight                        762.895 
_chem_comp.one_letter_code                       ? 
_chem_comp.three_letter_code                     9EA 
_chem_comp.pdbx_model_coordinates_details        ? 
_chem_comp.pdbx_model_coordinates_missing_flag   N 
_chem_comp.pdbx_ideal_coordinates_details        Corina 
_chem_comp.pdbx_ideal_coordinates_missing_flag   N 
_chem_comp.pdbx_model_coordinates_db_code        5VKC 
_chem_comp.pdbx_subcomponent_list                ? 
_chem_comp.pdbx_processing_site                  RCSB 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.alt_atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.charge 
_chem_comp_atom.pdbx_align 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_leaving_atom_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.model_Cartn_x 
_chem_comp_atom.model_Cartn_y 
_chem_comp_atom.model_Cartn_z 
_chem_comp_atom.pdbx_model_Cartn_x_ideal 
_chem_comp_atom.pdbx_model_Cartn_y_ideal 
_chem_comp_atom.pdbx_model_Cartn_z_ideal 
_chem_comp_atom.pdbx_component_atom_id 
_chem_comp_atom.pdbx_component_comp_id 
_chem_comp_atom.pdbx_ordinal 
9EA C4  C1  C 0 1 Y N N -28.548 4.827  3.562  -2.221 8.620  -0.700 C4  9EA 1   
9EA C5  C2  C 0 1 Y N N -32.499 2.905  10.466 7.473  -0.285 0.907  C5  9EA 2   
9EA C6  C3  C 0 1 Y N N -28.047 7.776  1.480  -5.715 7.650  -0.042 C6  9EA 3   
9EA C7  C4  C 0 1 Y N N -30.597 8.244  2.396  -4.435 5.171  0.130  C7  9EA 4   
9EA C8  C5  C 0 1 Y N N -31.142 7.910  7.315  2.206  1.346  -2.869 C8  9EA 5   
9EA C10 C6  C 0 1 Y N N -30.064 7.941  9.465  2.973  -0.907 -3.115 C10 9EA 6   
9EA C13 C7  C 0 1 Y N N -35.796 12.278 11.864 -2.325 -3.099 0.728  C13 9EA 7   
9EA C15 C8  C 0 1 Y N N -36.022 10.037 13.402 -1.338 -4.316 -1.560 C15 9EA 8   
9EA C17 C9  C 0 1 Y N N -32.545 2.519  11.783 7.811  0.238  2.142  C17 9EA 9   
9EA C20 C10 C 0 1 Y N N -29.930 7.097  2.800  -3.677 6.319  -0.153 C20 9EA 10  
9EA C21 C11 C 0 1 Y N N -32.298 7.451  7.923  2.491  1.298  -1.497 C21 9EA 11  
9EA C22 C12 C 0 1 Y N N -31.205 7.511  10.099 3.265  -0.985 -1.760 C22 9EA 12  
9EA C24 C13 C 0 1 Y N N -33.510 4.969  11.115 5.200  -0.313 1.618  C24 9EA 13  
9EA C26 C14 C 0 1 Y N N -32.323 7.271  9.302  3.026  0.124  -0.936 C26 9EA 14  
9EA C28 C15 C 0 1 Y N N -34.852 10.250 12.711 -0.470 -3.707 -0.665 C28 9EA 15  
9EA C1  C16 C 0 1 Y N N -28.714 8.915  1.087  -6.418 6.515  0.225  C1  9EA 16  
9EA C2  C17 C 0 1 Y N N -29.996 9.143  1.543  -5.780 5.279  0.308  C2  9EA 17  
9EA C3  C18 C 0 1 Y N N -30.035 8.133  8.104  2.447  0.256  -3.656 C3  9EA 18  
9EA C9  C19 C 0 1 Y N N -27.957 5.739  2.714  -3.566 8.726  -0.515 C9  9EA 19  
9EA C11 C20 C 0 1 Y N N -32.989 4.147  10.127 6.144  -0.568 0.635  C11 9EA 20  
9EA C12 C21 C 0 1 Y N N -37.067 10.930 13.317 -2.697 -4.316 -1.313 C12 9EA 21  
9EA C14 C22 C 0 1 Y N N -29.827 5.033  4.034  -1.580 7.387  -0.618 C14 9EA 22  
9EA C16 C23 C 0 1 Y N N -34.741 11.392 11.941 -0.966 -3.099 0.479  C16 9EA 23  
9EA C18 C24 C 0 1 Y N N -33.505 4.481  12.404 5.614  0.201  2.832  C18 9EA 24  
9EA C19 C25 C 0 1 Y N N -28.648 6.871  2.330  -4.325 7.577  -0.237 C19 9EA 25  
9EA C23 C26 C 0 1 Y N N -31.168 7.402  11.545 3.828  -2.233 -1.188 C23 9EA 26  
9EA C25 C27 C 0 1 Y N N -33.572 7.121  7.382  2.358  2.235  -0.444 C25 9EA 27  
9EA C27 C28 C 0 1 Y N N -36.995 12.075 12.533 -3.194 -3.708 -0.168 C27 9EA 28  
9EA C29 C29 C 0 1 Y N N -30.519 6.177  3.655  -2.283 6.247  -0.344 C29 9EA 29  
9EA C30 C30 C 0 1 Y N N -34.374 6.736  8.435  2.796  1.640  0.697  C30 9EA 30  
9EA C31 C31 C 0 1 Y N N -31.806 8.252  12.485 3.142  -3.162 -0.381 C31 9EA 31  
9EA C32 C32 C 0 1 Y N N -30.464 6.479  12.299 5.102  -2.693 -1.352 C32 9EA 32  
9EA C33 C33 C 0 1 N N N -35.764 6.340  8.428  2.830  2.266  2.025  C33 9EA 33  
9EA C34 C34 C 0 1 N N N -41.582 15.019 11.271 -8.133 -5.546 0.816  C34 9EA 34  
9EA C35 C35 C 0 1 N N N -39.408 12.322 12.523 -4.866 -4.295 1.398  C35 9EA 35  
9EA C36 C36 C 0 1 N N N -38.043 13.911 11.318 -5.301 -4.402 -0.986 C36 9EA 36  
9EA C37 C37 C 0 1 N N N -40.513 13.347 12.705 -6.355 -4.113 1.712  C37 9EA 37  
9EA C38 C38 C 0 1 N N N -39.103 14.990 11.450 -6.808 -4.225 -0.769 C38 9EA 38  
9EA C39 C39 C 0 1 N N N -29.586 5.341  11.947 6.194  -2.025 -2.148 C39 9EA 39  
9EA C40 C40 C 0 1 N N N -41.547 16.520 11.319 -8.538 -5.886 2.227  C40 9EA 40  
9EA C41 C41 C 0 1 N N N -30.294 6.117  14.795 6.408  -4.689 -0.581 C41 9EA 41  
9EA C42 C42 C 0 1 N N N -33.963 7.242  5.951  1.826  3.640  -0.567 C42 9EA 42  
9EA C43 C43 C 0 1 N N N -34.067 6.333  10.856 3.743  -0.609 1.372  C43 9EA 43  
9EA C44 C44 C 0 1 N N N -32.657 9.430  12.233 1.703  -3.062 0.055  C44 9EA 44  
9EA C45 C45 C 0 1 N N N -33.895 5.972  5.123  0.312  3.633  -0.347 C45 9EA 45  
9EA C46 C46 C 0 1 N N N -32.473 5.532  4.869  -0.228 5.059  -0.472 C46 9EA 46  
9EA N47 N1  N 0 1 Y N N -33.041 3.279  12.764 6.887  0.463  3.055  N47 9EA 47  
9EA N48 N2  N 0 1 Y N N -31.554 7.867  13.739 3.971  -4.125 -0.076 N48 9EA 48  
9EA N49 N3  N 0 1 Y N N -33.597 6.826  9.569  3.205  0.353  0.407  N49 9EA 49  
9EA N50 N4  N 0 1 Y N N -30.754 6.799  13.598 5.208  -3.854 -0.674 N50 9EA 50  
9EA N51 N5  N 0 1 N N N -38.103 12.988 12.450 -4.571 -3.708 0.083  N51 9EA 51  
9EA N52 N6  N 0 1 N N N -40.415 14.428 11.736 -7.138 -4.663 0.595  N52 9EA 52  
9EA O53 O1  O 0 1 N N N -36.620 6.727  9.202  3.288  1.571  3.086  O53 9EA 53  
9EA O54 O2  O 0 1 N N N -42.584 14.427 10.880 -8.701 -6.066 -0.120 O54 9EA 54  
9EA O55 O3  O 0 1 N N N -36.073 5.474  7.453  2.445  3.410  2.168  O55 9EA 55  
9EA O56 O4  O 0 1 N N N -33.896 9.248  12.895 0.868  -3.707 -0.909 O56 9EA 56  
9EA O57 O5  O 0 1 N N N -31.812 6.504  4.072  -1.643 5.052  -0.267 O57 9EA 57  
9EA H1  H1  H 0 1 N N N -28.004 3.943  3.860  -1.643 9.506  -0.918 H1  9EA 58  
9EA H2  H2  H 0 1 N N N -32.088 2.249  9.713  8.234  -0.466 0.163  H2  9EA 59  
9EA H3  H3  H 0 1 N N N -27.046 7.590  1.120  -6.223 8.601  -0.103 H3  9EA 60  
9EA H4  H4  H 0 1 N N N -31.598 8.434  2.754  -3.953 4.208  0.205  H4  9EA 61  
9EA H5  H5  H 0 1 N N N -31.109 8.089  6.250  1.791  2.243  -3.303 H5  9EA 62  
9EA H6  H6  H 0 1 N N N -29.174 8.132  10.046 3.157  -1.759 -3.752 H6  9EA 63  
9EA H7  H7  H 0 1 N N N -35.684 13.165 11.259 -2.710 -2.630 1.621  H7  9EA 64  
9EA H8  H8  H 0 1 N N N -36.123 9.157  14.020 -0.951 -4.789 -2.450 H8  9EA 65  
9EA H9  H9  H 0 1 N N N -32.158 1.544  12.041 8.844  0.465  2.360  H9  9EA 66  
9EA H10 H10 H 0 1 N N N -28.237 9.624  0.427  -7.486 6.574  0.375  H10 9EA 67  
9EA H11 H11 H 0 1 N N N -30.530 10.028 1.230  -6.361 4.394  0.521  H11 9EA 68  
9EA H12 H12 H 0 1 N N N -29.119 8.468  7.640  2.224  0.301  -4.712 H12 9EA 69  
9EA H13 H13 H 0 1 N N N -26.955 5.568  2.350  -4.048 9.691  -0.582 H13 9EA 70  
9EA H14 H14 H 0 1 N N N -32.968 4.478  9.099  5.850  -0.977 -0.321 H14 9EA 71  
9EA H15 H15 H 0 1 N N N -37.970 10.734 13.877 -3.372 -4.789 -2.010 H15 9EA 72  
9EA H16 H16 H 0 1 N N N -30.287 4.311  4.693  -0.513 7.331  -0.773 H16 9EA 73  
9EA H17 H17 H 0 1 N N N -33.828 11.591 11.399 -0.290 -2.626 1.175  H17 9EA 74  
9EA H18 H18 H 0 1 N N N -33.905 5.116  13.181 4.885  0.402  3.603  H18 9EA 75  
9EA H19 H19 H 0 1 N N N -39.582 11.762 11.592 -4.269 -3.796 2.161  H19 9EA 76  
9EA H20 H20 H 0 1 N N N -39.414 11.627 13.376 -4.624 -5.358 1.384  H20 9EA 77  
9EA H21 H21 H 0 1 N N N -38.211 13.351 10.386 -5.053 -5.463 -0.966 H21 9EA 78  
9EA H22 H22 H 0 1 N N N -37.049 14.382 11.288 -5.020 -3.980 -1.951 H22 9EA 79  
9EA H23 H23 H 0 1 N N N -40.442 13.770 13.718 -6.603 -4.646 2.630  H23 9EA 80  
9EA H24 H24 H 0 1 N N N -41.485 12.847 12.583 -6.577 -3.053 1.832  H24 9EA 81  
9EA H25 H25 H 0 1 N N N -38.820 15.668 12.268 -7.074 -3.175 -0.891 H25 9EA 82  
9EA H26 H26 H 0 1 N N N -39.155 15.555 10.507 -7.355 -4.831 -1.491 H26 9EA 83  
9EA H27 H27 H 0 1 N N N -28.544 5.688  11.880 6.824  -1.439 -1.479 H27 9EA 84  
9EA H28 H28 H 0 1 N N N -29.664 4.564  12.722 6.798  -2.784 -2.645 H28 9EA 85  
9EA H29 H29 H 0 1 N N N -29.897 4.925  10.977 5.749  -1.369 -2.896 H29 9EA 86  
9EA H30 H30 H 0 1 N N N -42.509 16.921 10.966 -7.882 -5.369 2.928  H30 9EA 87  
9EA H31 H31 H 0 1 N N N -41.370 16.850 12.353 -9.568 -5.572 2.395  H31 9EA 88  
9EA H32 H32 H 0 1 N N N -40.737 16.889 10.673 -8.457 -6.962 2.379  H32 9EA 89  
9EA H33 H33 H 0 1 N N N -30.703 6.619  15.684 7.000  -4.379 0.280  H33 9EA 90  
9EA H34 H34 H 0 1 N N N -30.635 5.072  14.775 6.116  -5.733 -0.464 H34 9EA 91  
9EA H35 H35 H 0 1 N N N -29.195 6.143  14.832 7.000  -4.576 -1.489 H35 9EA 92  
9EA H36 H36 H 0 1 N N N -33.297 7.982  5.484  2.299  4.274  0.183  H36 9EA 93  
9EA H37 H37 H 0 1 N N N -35.000 7.608  5.917  2.047  4.027  -1.562 H37 9EA 94  
9EA H38 H38 H 0 1 N N N -33.738 7.018  11.651 3.639  -1.619 0.975  H38 9EA 95  
9EA H39 H39 H 0 1 N N N -35.166 6.282  10.848 3.192  -0.529 2.309  H39 9EA 96  
9EA H40 H40 H 0 1 N N N -32.161 10.333 12.618 1.582  -3.548 1.023  H40 9EA 97  
9EA H41 H41 H 0 1 N N N -32.828 9.538  11.152 1.420  -2.013 0.137  H41 9EA 98  
9EA H42 H42 H 0 1 N N N -34.388 6.153  4.156  -0.161 2.999  -1.097 H42 9EA 99  
9EA H43 H43 H 0 1 N N N -34.423 5.170  5.660  0.091  3.246  0.647  H43 9EA 100 
9EA H44 H44 H 0 1 N N N -32.477 4.566  4.342  0.244  5.693  0.278  H44 9EA 101 
9EA H45 H45 H 0 1 N N N -31.946 5.424  5.828  -0.007 5.446  -1.467 H45 9EA 102 
9EA H46 H46 H 0 1 N N N -37.452 6.324  8.982  3.292  2.026  3.940  H46 9EA 103 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
9EA C1  C6  DOUB Y N 1   
9EA C1  C2  SING Y N 2   
9EA C6  C19 SING Y N 3   
9EA C2  C7  DOUB Y N 4   
9EA C19 C9  DOUB Y N 5   
9EA C19 C20 SING Y N 6   
9EA C7  C20 SING Y N 7   
9EA C9  C4  SING Y N 8   
9EA C20 C29 DOUB Y N 9   
9EA C4  C14 DOUB Y N 10  
9EA C29 C14 SING Y N 11  
9EA C29 O57 SING N N 12  
9EA O57 C46 SING N N 13  
9EA C46 C45 SING N N 14  
9EA C45 C42 SING N N 15  
9EA C42 C25 SING N N 16  
9EA C8  C21 DOUB Y N 17  
9EA C8  C3  SING Y N 18  
9EA C25 C21 SING Y N 19  
9EA C25 C30 DOUB Y N 20  
9EA O55 C33 DOUB N N 21  
9EA C21 C26 SING Y N 22  
9EA C3  C10 DOUB Y N 23  
9EA C33 C30 SING N N 24  
9EA C33 O53 SING N N 25  
9EA C30 N49 SING Y N 26  
9EA C26 N49 SING Y N 27  
9EA C26 C22 DOUB Y N 28  
9EA C10 C22 SING Y N 29  
9EA N49 C43 SING N N 30  
9EA C22 C23 SING N N 31  
9EA C11 C5  DOUB Y N 32  
9EA C11 C24 SING Y N 33  
9EA C5  C17 SING Y N 34  
9EA C43 C24 SING N N 35  
9EA O54 C34 DOUB N N 36  
9EA C24 C18 DOUB Y N 37  
9EA C34 C40 SING N N 38  
9EA C34 N52 SING N N 39  
9EA C36 C38 SING N N 40  
9EA C36 N51 SING N N 41  
9EA C38 N52 SING N N 42  
9EA C23 C32 DOUB Y N 43  
9EA C23 C31 SING Y N 44  
9EA N52 C37 SING N N 45  
9EA C17 N47 DOUB Y N 46  
9EA C13 C16 DOUB Y N 47  
9EA C13 C27 SING Y N 48  
9EA C16 C28 SING Y N 49  
9EA C39 C32 SING N N 50  
9EA C44 C31 SING N N 51  
9EA C44 O56 SING N N 52  
9EA C32 N50 SING Y N 53  
9EA C18 N47 SING Y N 54  
9EA N51 C35 SING N N 55  
9EA N51 C27 SING N N 56  
9EA C31 N48 DOUB Y N 57  
9EA C35 C37 SING N N 58  
9EA C27 C12 DOUB Y N 59  
9EA C28 O56 SING N N 60  
9EA C28 C15 DOUB Y N 61  
9EA C12 C15 SING Y N 62  
9EA N50 N48 SING Y N 63  
9EA N50 C41 SING N N 64  
9EA C4  H1  SING N N 65  
9EA C5  H2  SING N N 66  
9EA C6  H3  SING N N 67  
9EA C7  H4  SING N N 68  
9EA C8  H5  SING N N 69  
9EA C10 H6  SING N N 70  
9EA C13 H7  SING N N 71  
9EA C15 H8  SING N N 72  
9EA C17 H9  SING N N 73  
9EA C1  H10 SING N N 74  
9EA C2  H11 SING N N 75  
9EA C3  H12 SING N N 76  
9EA C9  H13 SING N N 77  
9EA C11 H14 SING N N 78  
9EA C12 H15 SING N N 79  
9EA C14 H16 SING N N 80  
9EA C16 H17 SING N N 81  
9EA C18 H18 SING N N 82  
9EA C35 H19 SING N N 83  
9EA C35 H20 SING N N 84  
9EA C36 H21 SING N N 85  
9EA C36 H22 SING N N 86  
9EA C37 H23 SING N N 87  
9EA C37 H24 SING N N 88  
9EA C38 H25 SING N N 89  
9EA C38 H26 SING N N 90  
9EA C39 H27 SING N N 91  
9EA C39 H28 SING N N 92  
9EA C39 H29 SING N N 93  
9EA C40 H30 SING N N 94  
9EA C40 H31 SING N N 95  
9EA C40 H32 SING N N 96  
9EA C41 H33 SING N N 97  
9EA C41 H34 SING N N 98  
9EA C41 H35 SING N N 99  
9EA C42 H36 SING N N 100 
9EA C42 H37 SING N N 101 
9EA C43 H38 SING N N 102 
9EA C43 H39 SING N N 103 
9EA C44 H40 SING N N 104 
9EA C44 H41 SING N N 105 
9EA C45 H42 SING N N 106 
9EA C45 H43 SING N N 107 
9EA C46 H44 SING N N 108 
9EA C46 H45 SING N N 109 
9EA O53 H46 SING N N 110 
# 
loop_
_pdbx_chem_comp_descriptor.comp_id 
_pdbx_chem_comp_descriptor.type 
_pdbx_chem_comp_descriptor.program 
_pdbx_chem_comp_descriptor.program_version 
_pdbx_chem_comp_descriptor.descriptor 
9EA SMILES           ACDLabs              12.01 "c2cc(c1ccccc1c2)OCCCc7c6cccc(c3c(n(C)nc3COc4ccc(cc4)N5CCN(C(C)=O)CC5)C)c6n(c7C(O)=O)Cc8cnccc8" 
9EA InChI            InChI                1.03  
;InChI=1S/C46H46N6O5/c1-31-43(41(48-49(31)3)30-57-36-20-18-35(19-21-36)51-25-23-50(24-26-51)32(2)53)40-15-7-14-38-39(16-9-27-56-42-17-6-12-34-11-4-5-13-37(34)42)45(46(54)55)52(44(38)40)29-33-10-8-22-47-28-33/h4-8,10-15,17-22,28H,9,16,23-27,29-30H2,1-3H3,(H,54,55)
;
9EA InChIKey         InChI                1.03  VKKQBUSCPZGZBT-UHFFFAOYSA-N 
9EA SMILES_CANONICAL CACTVS               3.385 "Cn1nc(COc2ccc(cc2)N3CCN(CC3)C(C)=O)c(c1C)c4cccc5c(CCCOc6cccc7ccccc67)c(n(Cc8cccnc8)c45)C(O)=O" 
9EA SMILES           CACTVS               3.385 "Cn1nc(COc2ccc(cc2)N3CCN(CC3)C(C)=O)c(c1C)c4cccc5c(CCCOc6cccc7ccccc67)c(n(Cc8cccnc8)c45)C(O)=O" 
9EA SMILES_CANONICAL "OpenEye OEToolkits" 2.0.6 "Cc1c(c(nn1C)COc2ccc(cc2)N3CCN(CC3)C(=O)C)c4cccc5c4n(c(c5CCCOc6cccc7c6cccc7)C(=O)O)Cc8cccnc8" 
9EA SMILES           "OpenEye OEToolkits" 2.0.6 "Cc1c(c(nn1C)COc2ccc(cc2)N3CCN(CC3)C(=O)C)c4cccc5c4n(c(c5CCCOc6cccc7c6cccc7)C(=O)O)Cc8cccnc8" 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
9EA "SYSTEMATIC NAME" ACDLabs              12.01 "7-(3-{[4-(4-acetylpiperazin-1-yl)phenoxy]methyl}-1,5-dimethyl-1H-pyrazol-4-yl)-3-{3-[(naphthalen-1-yl)oxy]propyl}-1-[(pyridin-3-yl)methyl]-1H-indole-2-carboxylic acid" 
9EA "SYSTEMATIC NAME" "OpenEye OEToolkits" 2.0.6 "7-[3-[[4-(4-ethanoylpiperazin-1-yl)phenoxy]methyl]-1,5-dimethyl-pyrazol-4-yl]-3-(3-naphthalen-1-yloxypropyl)-1-(pyridin-3-ylmethyl)indole-2-carboxylic acid"            
# 
loop_
_pdbx_chem_comp_audit.comp_id 
_pdbx_chem_comp_audit.action_type 
_pdbx_chem_comp_audit.date 
_pdbx_chem_comp_audit.processing_site 
9EA "Create component" 2017-04-24 RCSB 
9EA "Initial release"  2017-05-03 RCSB 
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