data_FAM_000279
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_pdbx_reference_molecule_family.family_prd_id   FAM_000279
_pdbx_reference_molecule_family.name            "HYDROLYTICALLY STABLE CYCLIC PEPTIDOMIMETIC INHIBITORS"
_pdbx_reference_molecule_family.release_status  REL
_pdbx_reference_molecule_family.replaces        ?
_pdbx_reference_molecule_family.replaced_by     ?
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_pdbx_reference_molecule_list.family_prd_id
_pdbx_reference_molecule_list.prd_id
FAM_000279   PRD_000407  
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_pdbx_reference_molecule_synonyms.family_prd_id
_pdbx_reference_molecule_synonyms.prd_id
_pdbx_reference_molecule_synonyms.ordinal
_pdbx_reference_molecule_synonyms.source
_pdbx_reference_molecule_synonyms.name
FAM_000279   PRD_000407   1     PDB          "1-{2-[(8R,11S)-8-(2-amino-2-oxoethyl)-6,9-dioxo-2-oxa-7,10-diazabicyclo[11.2.2]heptadeca-1(15),13,16-trien-11-yl]-2-oxoethyl}-L-prolyl-L-isoleucyl-L-valinamide"
FAM_000279   PRD_000407   2     PubChem      "Asn-Phe-Pro-Ile-Val Macrocylic deriv"
FAM_000279   PRD_000407   3     PubChem      "MACROCYCLIC PEPTIDOMIMETIC INHIBITOR 1"
FAM_000279   PRD_000407   4     PubChem      "PI1 1-[2-(8-CARBAMOYLMETHYL-6,9-DIOXO-2-OXA-7,10-DIAZA-BICYCLO[11.2.2] HEPTADECA-1(16),13(17),14-TRIEN-11-YL)-2-HYDROXY-ETHYL] -PYRROLIDINE-2-CARBOXYLIC ACID [1-(1-CARBAMOYL-2-METHYL-PROPYLCARBAMOYL) -2-METHYL-BUTYL]-AMIDE"
FAM_000279   PRD_000407   5     PubChem      "2-[((2S)-1-{(2S)-2-[(3S,6S)-4,7-Diaza-6-(carbamoylmethyl)-12-oxa-5,8-dioxobicyclo[11.2.2]heptadeca-1(15),13,16-trien-3-yl]-2-hydroxyethyl}pyrrolidin-2-yl)carbonylamino]-N-((1S)-1-carbamoyl-2-methylpropyl)(2S,3S)-3-methylpentanamide"
FAM_000279   PRD_000407   6     ChemSpider   "1-[2-(8-C ARBAMOYLMETHYL-6,9-DIOXO-2-OXA-7,10-DIAZA-BICYCLO[11.2.2] HEPTADECA-1(16),13(17),14-TRIEN-11-YL)-2-HYDROXY-ETHYL]-PYRROLIDINE-2-CARBOXYLIC ACID [1-(1-CARBAMOYL-2-METHYL-PROPYLCARBAMOYL) -2-METHYL-BUTYL]-AMIDE"
FAM_000279   PRD_000407   7     ChemSpider   "2-[((2S)-1-{(2S)-2-[(3S,6S)-4,7-Diaza-6-(carbamoylmethyl)-12-oxa-5,8-dio xobicyclo[11.2.2]heptadeca-1(15),13,16-trien-3-yl]-2-hydroxyeth yl}pyrrolidin-2-yl)carbonylamino]-N-((1S)-1-carbamoyl-2-methylp ropyl)(2S,3S)-3-methylpentanamide"
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_pdbx_reference_molecule_annotation.family_prd_id
_pdbx_reference_molecule_annotation.prd_id
_pdbx_reference_molecule_annotation.ordinal
_pdbx_reference_molecule_annotation.source
_pdbx_reference_molecule_annotation.type
_pdbx_reference_molecule_annotation.text
FAM_000279   PRD_000407   1     DOI:10.1021/ja00146a007 Function                  "Inhibitor of HIV-1 PROTEASE"
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_pdbx_reference_molecule_features.family_prd_id
_pdbx_reference_molecule_features.prd_id
_pdbx_reference_molecule_features.ordinal
_pdbx_reference_molecule_features.source_ordinal
_pdbx_reference_molecule_features.source
_pdbx_reference_molecule_features.type
_pdbx_reference_molecule_features.value
FAM_000279   PRD_000407   1     1     PubChem                External_reference_ID     444478
FAM_000279   PRD_000407   2     1     BindingDB              External_reference_ID     13927
FAM_000279   PRD_000407   3     1     ChemSpider             External_reference_ID     392402
FAM_000279   PRD_000407   4     1     CHEMBL                 External_reference_ID     1235296
#
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_pdbx_family_prd_audit.family_prd_id
_pdbx_family_prd_audit.date
_pdbx_family_prd_audit.processing_site
_pdbx_family_prd_audit.action_type
FAM_000279	2012-02-08	RCSB	"Create family"	
FAM_000279	2013-10-16	RCSB	"Initial release"	
#
