data_FAM_000218
#
_pdbx_reference_molecule_family.family_prd_id   FAM_000218
_pdbx_reference_molecule_family.name            H256
_pdbx_reference_molecule_family.release_status  REL
_pdbx_reference_molecule_family.replaces        ?
_pdbx_reference_molecule_family.replaced_by     ?
#
loop_
_pdbx_reference_molecule_list.family_prd_id
_pdbx_reference_molecule_list.prd_id
FAM_000218   PRD_000346  
#
loop_
_pdbx_reference_molecule_synonyms.family_prd_id
_pdbx_reference_molecule_synonyms.prd_id
_pdbx_reference_molecule_synonyms.ordinal
_pdbx_reference_molecule_synonyms.source
_pdbx_reference_molecule_synonyms.name
FAM_000218   PRD_000346   1     PDB          H256
FAM_000218   PRD_000346   2     Scifinder    "L-Glutamic acid, L-prolyl-L-threonyl-L-alpha-glutamyl-L-phenylalanyl-psi(CH2-NH)-L-phenylalanyl-L-arginyl-(9CI)"
FAM_000218   PRD_000346   3     Scifinder    "L-Glutamic acid, N-[N2-[N-[3-phenyl-2-[[N-(N-L-prolyl-L-threonyl)-L-alpha-glutamyl]amino]propyl]-L-phenylalanyl]-L-arginyl]-, (S)-"
FAM_000218   PRD_000346   4     Scifinder    "H 256 (proteinase inhibitor)"
FAM_000218   PRD_000346   5     PubChem      H256
FAM_000218   PRD_000346   6     PubChem      Pro-thr-glu-phe-CH2NH-phe-arg-glu
FAM_000218   PRD_000346   7     PubChem      "L-Glutamic acid, N-(N2-(N-(3-phenyl-2-((N-(N-L-prolyl-Lthreonyml)-L-alpha-glutamyl)amino)propyl)-L-phenylalanyl)-L-arginyl)-,(s)-"
FAM_000218   PRD_000346   8     ChemSpider   H256
FAM_000218   PRD_000346   9     ChemSpider   "L-Glutamic acid, N-(N2-(N-(3-phenyl-2-((N-(N-L-prolyl-L-threonyl)-L-alpha-glutamy l)amino)propyl)-L-phenylalanyl)-L-arginyl)-, (S)-"
FAM_000218   PRD_000346   10    ChemSpider   "Pro-thr-glu-phe-CH2NH-phe-arg-gluyl-2-((N-(N-L-prolyl-L-threonyl)-L-alpha-glutamy l)amino)propyl)-L-phenylalanyl)-L-arginyl)-, (S)-"
#
loop_
_pdbx_reference_molecule_annotation.family_prd_id
_pdbx_reference_molecule_annotation.prd_id
_pdbx_reference_molecule_annotation.ordinal
_pdbx_reference_molecule_annotation.source
_pdbx_reference_molecule_annotation.type
_pdbx_reference_molecule_annotation.text
FAM_000218   PRD_000346   1     PubChem              Function                  "inhibitor of pepsin"
FAM_000218   PRD_000346   2     PMID:3119339         Function                  "Inhibitor of ENDOTHIAPEPSIN, EC: 3.4.23.6"
FAM_000218   PRD_000346   3     PMID:3119339         "Mechanism of Action"     "in place of the scissile bond, a reduced peptide group which is resistant to hydrolysis and mimics the tetrahedral transition state"
#
loop_
_pdbx_reference_molecule_features.family_prd_id
_pdbx_reference_molecule_features.prd_id
_pdbx_reference_molecule_features.ordinal
_pdbx_reference_molecule_features.source_ordinal
_pdbx_reference_molecule_features.source
_pdbx_reference_molecule_features.type
_pdbx_reference_molecule_features.value
FAM_000218   PRD_000346   1     1     MeSH                   MeSH_Unique_ID            C054285
FAM_000218   PRD_000346   2     1     PubChem                External_reference_ID     146956
FAM_000218   PRD_000346   3     1     ChemSpider             External_reference_ID     129595
FAM_000218   PRD_000346   4     1     CAS                    External_reference_ID     100111-08-8
FAM_000218   PRD_000346   5     1     ChEBI                  External_reference_ID     252478
FAM_000218   PRD_000346   6     1     ChemIDplus             External_reference_ID     100111088
#
loop_
_pdbx_family_prd_audit.family_prd_id
_pdbx_family_prd_audit.date
_pdbx_family_prd_audit.processing_site
_pdbx_family_prd_audit.action_type
FAM_000218	2012-02-08	RCSB	"Create family"	
FAM_000218	2013-10-16	RCSB	"Initial release"	
#
