data_FAM_000246
#
_pdbx_reference_molecule_family.family_prd_id   FAM_000246
_pdbx_reference_molecule_family.name            "N alpha-tosylated piperidides of amidino-phenylalanine"
_pdbx_reference_molecule_family.release_status  REL
_pdbx_reference_molecule_family.replaces        ?
_pdbx_reference_molecule_family.replaced_by     ?
#
loop_
_pdbx_reference_molecule_list.family_prd_id
_pdbx_reference_molecule_list.prd_id
FAM_000246   PRD_000374  
#
loop_
_pdbx_reference_molecule_synonyms.family_prd_id
_pdbx_reference_molecule_synonyms.prd_id
_pdbx_reference_molecule_synonyms.ordinal
_pdbx_reference_molecule_synonyms.source
_pdbx_reference_molecule_synonyms.name
FAM_000246   PRD_000374   1     PDB          4-TAPAP
FAM_000246   PRD_000374   2     Scifinder    4-TAPAP
FAM_000246   PRD_000374   3     Scifinder    "S 2576"
FAM_000246   PRD_000374   4     Scifinder    "S 2576 (thrombin inhibitor)"
FAM_000246   PRD_000374   5     Scifinder    "Piperidine, 1-[3-[4-(aminoiminomethyl)phenyl]-2-[[(4-methylphenyl)sulfonyl]amino]-1-oxopropyl]-(9CI)"
FAM_000246   PRD_000374   6     Beilstein    4-[3-Oxo-3-piperidin-1-yl-2-(toluene-4-sulfonylamino)-propyl]-benzamidine
FAM_000246   PRD_000374   7     PubChem      4-tapap
FAM_000246   PRD_000374   8     PubChem      N-(p-Amidino-alpha-(piperidinocarbonyl)phenethyl)-p-toluenesulfonamide
FAM_000246   PRD_000374   9     PubChem      "Piperidine, 1-(3-(4-(aminoiminomethyl)phenyl)-2-((4-methylphenyl)sulfonylamino)-1-oxopropyl)-"
FAM_000246   PRD_000374   10    PubChem      N(alpha)-(4-Toluenesulfonyl)-4-amidinophenylalanylpiperidine
FAM_000246   PRD_000374   11    PubChem      "p-Toluenesulfonamide, N-(p-amidino-alpha-(piperidinocarbonyl)phenethyl)-"
FAM_000246   PRD_000374   12    PubChem      "Piperidine, 1-(3-(4-(aminoiminomethyl)phenyl)-2-(((4-methylphenyl)sulfonyl)amino)-1-oxopropyl)-, (+-)-"
FAM_000246   PRD_000374   13    ChemSpider   4-Tapap
FAM_000246   PRD_000374   14    ChemSpider   N(alpha)-(4-Toluenesulfonyl)-4-amidinophenylalanylpiperidine
FAM_000246   PRD_000374   15    ChemSpider   N-(p-Amidino-alpha-(piperidinocarbonyl)phenethyl)-p-toluenesulfonamide
FAM_000246   PRD_000374   16    ChemSpider   "Piperidine, 1-(3-(4-(aminoiminomethyl)phenyl)-2-((4-methylphenyl)sulfonylamino)-1-oxopropyl)-"
FAM_000246   PRD_000374   17    ChemSpider   "p-Toluenesulfonamide, N-(p-amidino-alpha-(piperidinocarbonyl)phenethyl)-lamino)-1-oxopropyl)-"
FAM_000246   PRD_000374   18    PubChem      3-[(S)-3-Oxo-3-piperidin-1-yl-2-(toluene-4-sulfonylamino)-propyl]-benzamidine
FAM_000246   PRD_000374   19    PubChem      3-[(2S)-2-[(4-methylphenyl)sulfonylamino]-3-oxo-3-piperidin-1-ylpropyl]benzenecarboximidamide
FAM_000246   PRD_000374   20    PubChem      "N(alpha)-tosyl-(3-amidinophenyl)alanine piperidide"
#
loop_
_pdbx_reference_molecule_annotation.family_prd_id
_pdbx_reference_molecule_annotation.prd_id
_pdbx_reference_molecule_annotation.ordinal
_pdbx_reference_molecule_annotation.source
_pdbx_reference_molecule_annotation.type
_pdbx_reference_molecule_annotation.text
FAM_000246   PRD_000374   1     PubChem              Function                  "binds to thrombin and trypsin"
FAM_000246   PRD_000374   2     PMID:1879520         Function                  "Inhibitor of TRYPSIN, EC:3.4.21.4"
#
loop_
_pdbx_reference_molecule_features.family_prd_id
_pdbx_reference_molecule_features.prd_id
_pdbx_reference_molecule_features.ordinal
_pdbx_reference_molecule_features.source_ordinal
_pdbx_reference_molecule_features.source
_pdbx_reference_molecule_features.type
_pdbx_reference_molecule_features.value
FAM_000246   PRD_000374   1     1     MeSH                   MeSH_Unique_ID            C070567
FAM_000246   PRD_000374   2     1     Beilstein              External_reference_ID     1274845
FAM_000246   PRD_000374   3     1     PubChem                External_reference_ID     133476
FAM_000246   PRD_000374   4     1     ChemSpider             External_reference_ID     117745
FAM_000246   PRD_000374   5     1     CAS                    External_reference_ID     73438-62-7
FAM_000246   PRD_000374   6     1     LeadScope              External_reference_ID     LS-154094
FAM_000246   PRD_000374   7     2     PubChem                External_reference_ID     447889
FAM_000246   PRD_000374   8     1     ChEBI                  External_reference_ID     338637
FAM_000246   PRD_000374   9     2     ChemSpider             External_reference_ID     394853
#
loop_
_pdbx_family_prd_audit.family_prd_id
_pdbx_family_prd_audit.date
_pdbx_family_prd_audit.processing_site
_pdbx_family_prd_audit.action_type
FAM_000246	2012-02-08	RCSB	"Create family"	
FAM_000246	2013-10-16	RCSB	"Initial release"	
#
