data_FAM_001005
#
_pdbx_reference_molecule_family.family_prd_id   FAM_001005
_pdbx_reference_molecule_family.name            Lisinopril
_pdbx_reference_molecule_family.release_status  REL
_pdbx_reference_molecule_family.replaces        ?
_pdbx_reference_molecule_family.replaced_by     ?
#
loop_
_pdbx_reference_molecule_list.family_prd_id
_pdbx_reference_molecule_list.prd_id
FAM_001005   PRD_000560  
#
_pdbx_reference_molecule_related_structures.family_prd_id  FAM_001005
_pdbx_reference_molecule_related_structures.ordinal        1
_pdbx_reference_molecule_related_structures.citation_id    1
_pdbx_reference_molecule_related_structures.db_name        CCDC
_pdbx_reference_molecule_related_structures.db_accession   NESDOE
_pdbx_reference_molecule_related_structures.db_code        ?
_pdbx_reference_molecule_related_structures.name           "bis((mu-2--N'-(S-1-Carboxy-3-phenylpropyl)-L-lysyl-L-proline)-aqua-copper(ii)) diperchlorate"
_pdbx_reference_molecule_related_structures.formula        "C42 H64 Cu2 N6 O12 2+, 2(Cl O4 -)"
#
loop_
_pdbx_reference_molecule_synonyms.family_prd_id
_pdbx_reference_molecule_synonyms.prd_id
_pdbx_reference_molecule_synonyms.ordinal
_pdbx_reference_molecule_synonyms.source
_pdbx_reference_molecule_synonyms.name
FAM_001005   PRD_000560   1     DrugBank     "Acercomp (AstraZeneca/Promed)"
FAM_001005   PRD_000560   2     DrugBank     Inhibril
FAM_001005   PRD_000560   3     DrugBank     "Linopril (Klinger (Brazil))"
FAM_001005   PRD_000560   4     DrugBank     "Lisinopril Dihydrate"
FAM_001005   PRD_000560   5     DrugBank     "Lisipril (Hexal (Czech Republic), Orion (Finland))"
FAM_001005   PRD_000560   6     DrugBank     Lysinopril
FAM_001005   PRD_000560   7     DrugBank     "Noperten (Dexa (Indonesia))"
FAM_001005   PRD_000560   8     DrugBank     Presiten
FAM_001005   PRD_000560   9     DrugBank     "Prinivil (Merck Frosst)"
FAM_001005   PRD_000560   10    DrugBank     "Sinopril (Eczacibasi (Russia))"
FAM_001005   PRD_000560   11    DrugBank     "Zestril (AstraZeneca)"
FAM_001005   PRD_000560   12    SciFinder    "Lisinopril dihydrate"
FAM_001005   PRD_000560   13    SciFinder    Ranolip
FAM_001005   PRD_000560   14    SciFinder    Nanopril
FAM_001005   PRD_000560   15    SciFinder    Noperten
FAM_001005   PRD_000560   16    SciFinder    Novatec
FAM_001005   PRD_000560   17    SciFinder    Presiten
FAM_001005   PRD_000560   18    SciFinder    Prinil
FAM_001005   PRD_000560   19    SciFinder    Prinivil
FAM_001005   PRD_000560   20    SciFinder    Prinvil
FAM_001005   PRD_000560   21    SciFinder    Tensopril
FAM_001005   PRD_000560   22    SciFinder    Tensyn
FAM_001005   PRD_000560   23    SciFinder    Vivatec
FAM_001005   PRD_000560   24    SciFinder    Zestril
FAM_001005   PRD_000560   25    PubChem      Acerbon
FAM_001005   PRD_000560   26    PubChem      Acercomp
FAM_001005   PRD_000560   27    PubChem      Alapril
FAM_001005   PRD_000560   28    PubChem      Carace
FAM_001005   PRD_000560   29    PubChem      Cipral
FAM_001005   PRD_000560   30    PubChem      Cipril
FAM_001005   PRD_000560   31    PubChem      Coric
FAM_001005   PRD_000560   32    PubChem      Doneka
FAM_001005   PRD_000560   33    PubChem      Inhibril
FAM_001005   PRD_000560   34    PubChem      Inopril
FAM_001005   PRD_000560   35    PubChem      Linopril
FAM_001005   PRD_000560   36    PubChem      Linvas
FAM_001005   PRD_000560   37    PubChem      Lipril
FAM_001005   PRD_000560   38    PubChem      Lisinal
FAM_001005   PRD_000560   39    PubChem      Lisinopril
FAM_001005   PRD_000560   40    PubChem      Lisinoprilum
FAM_001005   PRD_000560   41    PubChem      Lisipril
FAM_001005   PRD_000560   42    PubChem      Lisoril
FAM_001005   PRD_000560   43    PubChem      Lispril
FAM_001005   PRD_000560   44    PubChem      Longes
FAM_001005   PRD_000560   45    PubChem      Loril
FAM_001005   PRD_000560   46    PubChem      Lysinopril
FAM_001005   PRD_000560   47    PubChem      Noperten
FAM_001005   PRD_000560   48    PubChem      Novatec
FAM_001005   PRD_000560   49    PubChem      Presiten
FAM_001005   PRD_000560   50    PubChem      Prinil
FAM_001005   PRD_000560   51    PubChem      Prinivil
FAM_001005   PRD_000560   52    PubChem      Sinopril
FAM_001005   PRD_000560   53    PubChem      Sinopryl
FAM_001005   PRD_000560   54    PubChem      Tensopril
FAM_001005   PRD_000560   55    PubChem      Tensyn
FAM_001005   PRD_000560   56    PubChem      Tersif
FAM_001005   PRD_000560   57    PubChem      Vivatec
FAM_001005   PRD_000560   58    PubChem      Zestril
FAM_001005   PRD_000560   59    PubChem      1-(N2-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline
FAM_001005   PRD_000560   60    PubChem      1-[Nalpha-[(S)-1-Carboxy-3-phenylpropyl]-L-lysyl]-L-proline
FAM_001005   PRD_000560   61    PubChem      "(2S)-1-[(2S)-6-amino-2-[[(2S)-1-hydroxy-1-oxo-4-phenylbutan-2-yl]amino]hexanoyl]pyrrolidine-2-carboxylic acid"
FAM_001005   PRD_000560   62    PubChem      "L-Proline, 1-(N2-(1-carboxy-3-phenylpropyl)-L-lysyl)-"
FAM_001005   PRD_000560   63    PubChem      "L-Proline, 1-(N2-(1-carboxy-3-phenylpropyl)-L-lysyl)-, dihydrate, (S)-"
FAM_001005   PRD_000560   64    PubChem      "L-Proline, 1-(N(sup 2)-(1-carboxy-3-phenylpropyl)-L-lysyl)-, (S)-"
FAM_001005   PRD_000560   65    PubChem      "L-Proline, N2-((1S)-1-carboxy-3-phenylpropyl)-L-lysyl-"
FAM_001005   PRD_000560   66    PubChem      N-(1(S)-Carboxy-3-phenylpropyl)-L-lysyl-L-proline
FAM_001005   PRD_000560   67    PubChem      N(2)-[(1S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-proline
FAM_001005   PRD_000560   68    PubChem      N2-[(1S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-proline
FAM_001005   PRD_000560   69    PubChem      N2-((S)-1-Carboxy-3-phenylpropyl)-L-lysyl-L-proline
FAM_001005   PRD_000560   70    PubChem      [N2-[(S)-1-CARBOXY-3-PHENYLPROPYL]-L-LYSYL-L-PROLINE
FAM_001005   PRD_000560   71    PubChem      (S)-1-(N(2)-(1-carboxy-3-phenylpropyl)-L-lysyl)-L-proline
FAM_001005   PRD_000560   72    PubChem      (S)-1-(N2-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline
FAM_001005   PRD_000560   73    PubChem      "(S)-1-(N(sup 2)-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline"
FAM_001005   PRD_000560   74    PDB          [N2-[(S)-1-CARBOXY-3-PHENYLPROPYL]-L-LYSYL-L-PROLINE
#
loop_
_pdbx_reference_molecule_annotation.family_prd_id
_pdbx_reference_molecule_annotation.prd_id
_pdbx_reference_molecule_annotation.ordinal
_pdbx_reference_molecule_annotation.source
_pdbx_reference_molecule_annotation.type
_pdbx_reference_molecule_annotation.text
FAM_001005   PRD_000560   1     MESH                 Function
;One of the ANGIOTENSIN-CONVERTING ENZYME INHIBITORS (ACE inhibitors), orally active, that has been used inthe treatment of hypertension and congestive heart failure.
;
FAM_001005   PRD_000560   2     PDB                  Structure
;Lisinopril is the lysine ester of enalaprilat, the active form of the prodrug enalapril, lisinopril isactive unchanged.
;
#
loop_
_pdbx_reference_molecule_features.family_prd_id
_pdbx_reference_molecule_features.prd_id
_pdbx_reference_molecule_features.ordinal
_pdbx_reference_molecule_features.source_ordinal
_pdbx_reference_molecule_features.source
_pdbx_reference_molecule_features.type
_pdbx_reference_molecule_features.value
FAM_001005   PRD_000560   1     1     ATCcode                External_Reference_ID     C09AA03
FAM_001005   PRD_000560   2     1     BIDD                   External_Reference_ID     GT0755
FAM_001005   PRD_000560   3     1     BindingDB              External_Reference_ID     50189453
FAM_001005   PRD_000560   4     1     CAS                    External_Reference_ID     76547-98-3
FAM_001005   PRD_000560   5     2     CAS                    External_Reference_ID     77726-95-5
FAM_001005   PRD_000560   6     3     CAS                    External_Reference_ID     82009-35-6
FAM_001005   PRD_000560   7     4     CAS                    External_Reference_ID     83915-83-7
FAM_001005   PRD_000560   8     5     CAS                    External_Reference_ID     94133-19-4
FAM_001005   PRD_000560   9     1     CCRIS                  External_Reference_ID     3568
FAM_001005   PRD_000560   10    1     ChEBI                  External_Reference_ID     43755
FAM_001005   PRD_000560   11    1     ChEMBL                 External_Reference_ID     1237
FAM_001005   PRD_000560   12    1     ChemIDplus             External_Reference_ID     076547983
FAM_001005   PRD_000560   13    2     ChemIDplus             External_Reference_ID     077726955
FAM_001005   PRD_000560   14    1     ChemSpider             External_Reference_ID     4514933
FAM_001005   PRD_000560   15    1     DrugBank               External_Reference_ID     DB00722
FAM_001005   PRD_000560   16    1     EINECS                 External_Reference_ID     278-488-1
FAM_001005   PRD_000560   17    1     KEGG                   KEGG_Drug_ID              D00362
FAM_001005   PRD_000560   18    2     KEGG                   KEGG_Drug_ID              D08131
FAM_001005   PRD_000560   19    1     LeadScope              External_Reference_ID     LS-118899
FAM_001005   PRD_000560   20    1     MESH                   External_Reference_ID     D017706
FAM_001005   PRD_000560   21    1     MolPort                External_Reference_ID     MolPort-002-507-428
FAM_001005   PRD_000560   22    1     PubChem                External_Reference_ID     5362119
FAM_001005   PRD_000560   23    1     Wikipedia              URL                       http://en.wikipedia.org/wiki/Lisinopril
FAM_001005   PRD_000560   24    1     Wikipedia              Image                     http://upload.wikimedia.org/wikipedia/commons/1/13/Lisinopril.svg
#
_citation.id                       1
_citation.year                     1997
_citation.journal_volume           13
_citation.page_first               2377
_citation.page_last                2380
_citation.pdbx_database_id_DOI     10.1039/A701500C
_citation.pdbx_database_id_PubMed  ?
_citation.title                    " Metal complexes of the angiotensin-converting enzyme inhibitor, lisinopril. Solution studies and the crystal and molecular structure of a dimeric copper(II)-lisinopril complex"
_citation.journal_abbrev           "J. Chem. Soc. Dalton Transactions"
#
loop_
_citation_author.citation_id
_citation_author.ordinal
_citation_author.name
1  1  "Gonzalez, E.B."  
1  2  "Farkas, E."  
1  3  "Soudi, A.A."  
1  4  "Tan, T."  
1  5  "Yanovsky, A.I."  
1  6  "Nolan, K.B."  
#
loop_
_pdbx_family_prd_audit.family_prd_id
_pdbx_family_prd_audit.date
_pdbx_family_prd_audit.processing_site
_pdbx_family_prd_audit.action_type
FAM_001005	2012-02-08	RCSB	"Create family"	
FAM_001005	2013-10-16	RCSB	"Initial release"	
#
