data_FAM_000275
#
_pdbx_reference_molecule_family.family_prd_id   FAM_000275
_pdbx_reference_molecule_family.name            "dihydroxyethylene isostere containing peptide-mimetic inhibitor"
_pdbx_reference_molecule_family.release_status  REL
_pdbx_reference_molecule_family.replaces        ?
_pdbx_reference_molecule_family.replaced_by     ?
#
loop_
_pdbx_reference_molecule_list.family_prd_id
_pdbx_reference_molecule_list.prd_id
FAM_000275   PRD_000403  
#
loop_
_pdbx_reference_molecule_synonyms.family_prd_id
_pdbx_reference_molecule_synonyms.prd_id
_pdbx_reference_molecule_synonyms.ordinal
_pdbx_reference_molecule_synonyms.source
_pdbx_reference_molecule_synonyms.name
FAM_000275   PRD_000403   1     Scifinder    "L-Idonamide, 6-cyclohexyl-2,5,6-trideoxy-5-[[(2S)-3-(1H-imidazol-4-yl)-2-[[(1-naphthalenyloxy)acetyl]amino]-1-oxopropyl]amino]-2-(1-methylethyl)-N-[(1S,2S)-2-methyl-1-[[(2-pyridinylmethyl)amino]carbonyl]butyl]-(9CI)"
FAM_000275   PRD_000403   2     Scifinder    "L-Idonamide, 6-cyclohexyl-2,5,6-trideoxy-5-[[3-(1H-imidazol-4-yl)-2-[[(1-naphthalenyloxy)acetyl]amino]-1-oxopropyl]amino]-2-(1-methylethyl)-N-[2-methyl-1-[[(2-pyridinylmethyl)amino]carbonyl]butyl]-, [1(1S,2S),5(S)]-"
FAM_000275   PRD_000403   3     Scifinder    "U 75875"
FAM_000275   PRD_000403   4     Beilstein    "(2R,3R,4R,5S)-6-Cyclohexyl-3,4-dihydroxy-5-{(S)-3-(1H-imidazol-4-yl)-2-[2-(naphthalen-1-yloxy)-acetylamino]-propionylamino}-2-isopropyl-hexanoic acid {(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butyl}-amide"
FAM_000275   PRD_000403   5     PubChem      "NOA-HIS-CAV-ILE-APY Pnu-75875"
FAM_000275   PRD_000403   6     PubChem      Noa-His-Cha.psi.[CHOHCHOH]Val-Ile-Amp
FAM_000275   PRD_000403   7     PubChem      "U 75875"
FAM_000275   PRD_000403   8     PubChem      Noa-his-cha-psi(CH(OH)CH(OH))-val-ile-amp
FAM_000275   PRD_000403   9     PubChem      1-Naphthoxyacetyl-histidyl-5-amino-6-cyclohexyl-3,4-dihydroxy-2-isopropylhexanoyl-isoleucyl-2-aminopyridine
FAM_000275   PRD_000403   10    PubChem      "L-Idonamide, 6-cyclohexyl-2,5,6-trideoxy-5-((3-(1H-imidazol-4-yl)-2-(((1-naphthalenyloxy)acetyl)amino)-1-oxopropyl)amino)-2-(1-methylethyl)-N-(2-methyl-1-(((2-pyridinylmethyl)amino)carbonyl)butyl)-, (1(1S,2S),5(S))-"
FAM_000275   PRD_000403   11    PubChem      "L-Idonamide, 6-cyclohexyl-2,5,6-trideoxy-5-[[(2S)-3-(1H-imidazol-4-yl)-2-[[(1-naphthalenyloxy)acetyl]amino]-1-oxopropyl]amino]-2-(1-methylethyl)-N-[(1S,2S)-2-methyl-1-[[(2-pyridinylmethyl)amino]carbonyl]butyl]"
FAM_000275   PRD_000403   12    ChemSpider   1-Naphthoxyacetyl-histidyl-5-amino-6-cyclohexyl-3,4-dihydroxy-2-isopropylhexanoyl-isoleucyl-2-aminopyridine
FAM_000275   PRD_000403   13    ChemSpider   "L-Idonami de, 6-cyclohexyl-2,5,6-trideoxy-5-((3-(1H-imidazol-4-yl)-2-(((1 -naphthalenyloxy)acetyl)amino)-1-oxopropyl)amino)-2-(1-methylet hyl)-N-(2-methyl-1-(((2-pyridinylmethyl)amino)carbonyl)butyl)-, (1(1S,2S),5(S))-"
FAM_000275   PRD_000403   14    ChemSpider   "L-Idonami de, 6-cyclohexyl-2,5,6-trideoxy-5-[[(2S)-3-(1H-imidazol-4-yl)-2 -[[(1-naphthalenyloxy)acetyl]amino]-1-oxopropyl]amino]-2-(1-met hylethyl)-N-[(1S,2S)-2-methyl-1-[[(2-pyridinylmethyl)amino]carb onyl]butyl](S))-"
FAM_000275   PRD_000403   15    ChemSpider   "NOA-HIS-CAV-ILE-APYclohexyl-2,5,6-trideoxy-5-[[(2S)-3-(1H-imidazol-4-yl)-2 -[[(1-naphthalenyloxy)acetyl]amino]-1-oxopropyl]amino]-2-(1-met hylethyl)-N-[(1S,2S)-2-methyl-1-[[(2-pyridinylmethyl)amino]carb onyl]butyl](S))-"
FAM_000275   PRD_000403   16    ChemSpider   "Noa-His-Cha.psi.[CHOHCHOH]Val-Ile-Ampeoxy-5-[[(2S)-3-(1H-imidazol-4-yl)-2 -[[(1-naphthalenyloxy)acetyl]amino]-1-oxopropyl]amino]-2-(1-met hylethyl)-N-[(1S,2S)-2-methyl-1-[[(2-pyridinylmethyl)amino]carb onyl]butyl](S))-"
FAM_000275   PRD_000403   17    ChemSpider   "Noa-his-cha-psi(CH(OH)CH(OH))-val-ile-amp-5-[[(2S)-3-(1H-imidazol-4-yl)-2 -[[(1-naphthalenyloxy)acetyl]amino]-1-oxopropyl]amino]-2-(1-met hylethyl)-N-[(1S,2S)-2-methyl-1-[[(2-pyridinylmethyl)amino]carb onyl]butyl](S))-"
FAM_000275   PRD_000403   18    ChemSpider   "U75875s-cha-psi(CH(OH)CH(OH))-val-ile-amp-5-[[(2S)-3-(1H-imidazol-4-yl)-2 -[[(1-naphthalenyloxy)acetyl]amino]-1-oxopropyl]amino]-2-(1-met hylethyl)-N-[(1S,2S)-2-methyl-1-[[(2-pyridinylmethyl)amino]carb onyl]butyl](S))-"
#
loop_
_pdbx_reference_molecule_annotation.family_prd_id
_pdbx_reference_molecule_annotation.prd_id
_pdbx_reference_molecule_annotation.ordinal
_pdbx_reference_molecule_annotation.source
_pdbx_reference_molecule_annotation.type
_pdbx_reference_molecule_annotation.text
FAM_000275   PRD_000403   1     PMID:1304383         Function                  "Inhibitor of HIV-1 PROTEASE, EC: 3.4.23.47"
#
loop_
_pdbx_reference_molecule_features.family_prd_id
_pdbx_reference_molecule_features.prd_id
_pdbx_reference_molecule_features.ordinal
_pdbx_reference_molecule_features.source_ordinal
_pdbx_reference_molecule_features.source
_pdbx_reference_molecule_features.type
_pdbx_reference_molecule_features.value
FAM_000275   PRD_000403   1     1     PubChem                External_reference_ID     5479205
FAM_000275   PRD_000403   2     1     CAS                    External_reference_ID     112190-24-6
FAM_000275   PRD_000403   3     2     PubChem                External_reference_ID     5496609
FAM_000275   PRD_000403   4     2     ChemSpider             External_reference_ID     4593413
FAM_000275   PRD_000403   5     1     ChemIDplus             External_reference_ID     112190246
FAM_000275   PRD_000403   6     1     MESH                   External_reference_ID     C065978
#
loop_
_pdbx_family_prd_audit.family_prd_id
_pdbx_family_prd_audit.date
_pdbx_family_prd_audit.processing_site
_pdbx_family_prd_audit.action_type
FAM_000275	2012-02-08	RCSB	"Create family"	
FAM_000275	2013-10-16	RCSB	"Initial release"	
#
