data_FAM_000194
#
_pdbx_reference_molecule_family.family_prd_id   FAM_000194
_pdbx_reference_molecule_family.name            "vinyl sulfone containing inhibitor, APC 3316"
_pdbx_reference_molecule_family.release_status  REL
_pdbx_reference_molecule_family.replaces        ?
_pdbx_reference_molecule_family.replaced_by     ?
#
loop_
_pdbx_reference_molecule_list.family_prd_id
_pdbx_reference_molecule_list.prd_id
FAM_000194   PRD_000325  
#
loop_
_pdbx_reference_molecule_synonyms.family_prd_id
_pdbx_reference_molecule_synonyms.prd_id
_pdbx_reference_molecule_synonyms.ordinal
_pdbx_reference_molecule_synonyms.source
_pdbx_reference_molecule_synonyms.name
FAM_000194   PRD_000325   1     Scifinder    "1-Piperazinecarboxamide, 4-methyl-N-[(1S)-2-oxo-2-[[(1S)-1-(2-phenylethyl)-3-(phenylsulfonyl)-2-propenyl]amino]-1-(phenylmethyl)ethyl]-(9CI)"
FAM_000194   PRD_000325   2     Scifinder    "APC 3316"
FAM_000194   PRD_000325   3     Scifinder    "K 11777"
FAM_000194   PRD_000325   4     Scifinder    "K 777"
FAM_000194   PRD_000325   5     PubChem
;4-methyl-N-((S)-1-oxo-3-phenyl-1-((S)-5-phenyl-1-(phenylsulfonyl)pent-1-en-3-ylamino)propan-2-yl)piperazine-1-carboxamide
;
FAM_000194   PRD_000325   6     PubChem
;4-Methyl-piperazine-1-carboxylic acid [(S)-1-((E)-(S)-3-benzenesulfonyl-1-phenethyl-allylcarbamoyl)-2-phenyl-ethyl]-amide
;
FAM_000194   PRD_000325   7     PubChem      "4-Methylpiperazine-1-carboxylic acid [1-[(3-benzenesulfonyl-1-phenethylallyl]carbamoyl)-2-phenylethyl]amide"
FAM_000194   PRD_000325   8     PubChem
;N-[(2S)-1-[[(E,3S)-1-(benzenesulfonyl)-5-phenylpent-1-en-3-yl]amino]-1-oxo-3-phenylpropan-2-yl]-4-methylpiperazine-1-carboxamide
;
#
loop_
_pdbx_reference_molecule_annotation.family_prd_id
_pdbx_reference_molecule_annotation.prd_id
_pdbx_reference_molecule_annotation.ordinal
_pdbx_reference_molecule_annotation.source
_pdbx_reference_molecule_annotation.type
_pdbx_reference_molecule_annotation.text
FAM_000194   PRD_000325   1     PMID:11027133        Function                  "inhibitor of Cathepsin V, EC: 3.4.22.43"
FAM_000194   PRD_000325   2     PMID:21832058        Function                  "inhibitor of Cathepsin B-like peptidase (C01 family), EC: 3.4.22.1"
#
loop_
_pdbx_reference_molecule_features.family_prd_id
_pdbx_reference_molecule_features.prd_id
_pdbx_reference_molecule_features.ordinal
_pdbx_reference_molecule_features.source_ordinal
_pdbx_reference_molecule_features.source
_pdbx_reference_molecule_features.type
_pdbx_reference_molecule_features.value
FAM_000194   PRD_000325   1     1     PubChem                External_reference_ID     9851116
FAM_000194   PRD_000325   2     1     ChEBI                  External_reference_ID     251502
FAM_000194   PRD_000325   3     1     ChemSpider             External_reference_ID     8026829
FAM_000194   PRD_000325   4     1     CAS                    External_reference_ID     233277-99-1
#
loop_
_pdbx_family_prd_audit.family_prd_id
_pdbx_family_prd_audit.date
_pdbx_family_prd_audit.processing_site
_pdbx_family_prd_audit.action_type
FAM_000194	2012-02-08	RCSB	"Create family"	
FAM_000194	2013-10-16	RCSB	"Initial release"	
#
