data_FAM_000352
#
_pdbx_reference_molecule_family.family_prd_id   FAM_000352
_pdbx_reference_molecule_family.name            Largazole
_pdbx_reference_molecule_family.release_status  REL
_pdbx_reference_molecule_family.replaces        ?
_pdbx_reference_molecule_family.replaced_by     ?
#
loop_
_pdbx_reference_molecule_list.family_prd_id
_pdbx_reference_molecule_list.prd_id
FAM_000352   PRD_000785  
#
loop_
_pdbx_reference_molecule_synonyms.family_prd_id
_pdbx_reference_molecule_synonyms.prd_id
_pdbx_reference_molecule_synonyms.ordinal
_pdbx_reference_molecule_synonyms.source
_pdbx_reference_molecule_synonyms.name
FAM_000352   PRD_000785   1     SciFinder    "Octanethioic acid, S-[(3E)-4-[(5R,8S,11S)-5-methyl-8-(1-methylethyl)-6,9,13-trioxo-10-oxa-3,17-dithia-7,14,19,20-tetraazatricyclo[14.2.1.12,5]eicosa-2(20),16(19),18-trien-11-yl]-3-buten-1-yl] ester"
#
loop_
_pdbx_reference_molecule_annotation.family_prd_id
_pdbx_reference_molecule_annotation.prd_id
_pdbx_reference_molecule_annotation.ordinal
_pdbx_reference_molecule_annotation.source
_pdbx_reference_molecule_annotation.type
_pdbx_reference_molecule_annotation.text
FAM_000352   PRD_000785   1     PMID:21790156        Function                  "most potent inhibitor of the metal-dependent histone deacetylases (HDACs)"
FAM_000352   PRD_000785   2     PMID:21790156        Function                  "inhibitor of Histone deacetylase 8, EC: 3.5.1.98"
#
loop_
_pdbx_reference_molecule_features.family_prd_id
_pdbx_reference_molecule_features.prd_id
_pdbx_reference_molecule_features.ordinal
_pdbx_reference_molecule_features.source_ordinal
_pdbx_reference_molecule_features.source
_pdbx_reference_molecule_features.type
_pdbx_reference_molecule_features.value
FAM_000352   PRD_000785   1     1     PubChem                External_Reference_ID     53338884
FAM_000352   PRD_000785   2     1     ChemSpider             External_Reference_ID     24747365
FAM_000352   PRD_000785   3     1     CAS                    External_Reference_ID     1009815-87-5
#
loop_
_pdbx_family_prd_audit.family_prd_id
_pdbx_family_prd_audit.date
_pdbx_family_prd_audit.processing_site
_pdbx_family_prd_audit.action_type
FAM_000352	2012-09-13	RCSB	"Create family"	
FAM_000352	2013-10-16	RCSB	"Initial release"	
#
