data_FAM_000252
#
_pdbx_reference_molecule_family.family_prd_id   FAM_000252
_pdbx_reference_molecule_family.name            "SUCCINYL-PEPTIDE-CHLOROMETHYLKETONE INHIBITORS"
_pdbx_reference_molecule_family.release_status  REL
_pdbx_reference_molecule_family.replaces        ?
_pdbx_reference_molecule_family.replaced_by     ?
#
loop_
_pdbx_reference_molecule_list.family_prd_id
_pdbx_reference_molecule_list.prd_id
FAM_000252   PRD_000381  
FAM_000252   PRD_000402  
FAM_000252   PRD_000414  
#
loop_
_pdbx_reference_molecule_synonyms.family_prd_id
_pdbx_reference_molecule_synonyms.prd_id
_pdbx_reference_molecule_synonyms.ordinal
_pdbx_reference_molecule_synonyms.source
_pdbx_reference_molecule_synonyms.name
FAM_000252   PRD_000381   1     ChemSpider   L-alanyl-L-alanyl-N-[(1S)-1-benzyl-3-chloro-2-oxopropyl]-L-prolinamide
FAM_000252   PRD_000402   2     PDB          MSACK
FAM_000252   PRD_000402   3     Scifinder    "L-Prolinamide, N-(4-methoxy-1,4-dioxobutyl)-L-alanyl-L-alanyl-N-[(1S)-3-chloro-1-methyl-2-oxopropyl]-"
FAM_000252   PRD_000402   4     Scifinder    "L-Prolinamide, N-(4-methoxy-1,4-dioxobutyl)-L-alanyl-L-alanyl-N-(3-chloro-1-methyl-2-oxopropyl)-, (S)-"
FAM_000252   PRD_000402   5     PubChem      "Methoxysuccinyl-alanyl-alanyl-prolyl-alanine chloromethyl ketone"
FAM_000252   PRD_000402   6     PubChem      "L-Prolinamide, N-(4-methoxy-1,4-dioxobutyl)-L-alanyl-L-alanyl-N-(3-chloro-1-methyl-2-oxopropyl)-, (S)-"
FAM_000252   PRD_000402   7     PubChem      MeOSuc-Ala-Ala-Pro-Ala-CMK
FAM_000252   PRD_000402   8     PubChem      MeOSuc-Ala-Ala-Pro-Ala-Chloromethylketone
FAM_000252   PRD_000402   9     ChemSpider   "Methoxysuccinyl-alanyl-alanyl-prolyl-alanine chloromethyl ketone"
FAM_000252   PRD_000414   10    SciFinder    "L-Prolinamide, N-(4-methoxy-1,4-dioxobutyl)-L-alanyl-L-alanyl-N-[(1S)-3-chloro-1-(1-methylethyl)-2-oxopropyl]-"
FAM_000252   PRD_000414   11    SciFinder    "L-Prolinamide, N-(4-methoxy-1,4-dioxobutyl)-L-alanyl-L-alanyl-N-[3-chloro-1-(1-methylethyl)-2-oxopropyl]-, (S)-"
FAM_000252   PRD_000414   12    SciFinder    "Elastase inhibitor III"
FAM_000252   PRD_000414   13    SciFinder    SPCK
FAM_000252   PRD_000414   14    ChemSpider   MeOSuc-AAPV-CMK
FAM_000252   PRD_000414   15    ChemSpider   MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE
FAM_000252   PRD_000414   16    ChemSpider   "methoxy-Suc-Ala-Ala-Pro-Val-chloromethyl ketone"
FAM_000252   PRD_000414   17    ChemSpider   "methoxysuccinyl-alanyl-alanyl-prolyl-valine chloromethyl ketone"
FAM_000252   PRD_000414   18    ChemSpider   MSAAPVCK
FAM_000252   PRD_000414   19    ChemSpider   "N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone"
FAM_000252   PRD_000414   20    ChemSpider   "N-(Methoxysuccinyl)-L-alanyl-L-alanyl-L-prolyl-L-valine chloromethylketone"
#
loop_
_pdbx_reference_molecule_annotation.family_prd_id
_pdbx_reference_molecule_annotation.prd_id
_pdbx_reference_molecule_annotation.ordinal
_pdbx_reference_molecule_annotation.source
_pdbx_reference_molecule_annotation.type
_pdbx_reference_molecule_annotation.text
FAM_000252   PRD_000381   1     PMID:9931257         Function                  "Inhitor of CHYMASE, MAST CELL PROTEASE I, EC: 3.4.21.39"
FAM_000252   PRD_000402   2     PMID:2911584         Function                  "Inhibitor of HUMAN LEUCOCYTE ELASTASE, EC: 3.4.21.37"
FAM_000252   PRD_000414   3     PMID:3391280         Function                  "Inhibitor of HUMAN LEUKOCYTE ELASTASE, EC: 3.4.21.37"
#
loop_
_pdbx_reference_molecule_features.family_prd_id
_pdbx_reference_molecule_features.prd_id
_pdbx_reference_molecule_features.ordinal
_pdbx_reference_molecule_features.source_ordinal
_pdbx_reference_molecule_features.source
_pdbx_reference_molecule_features.type
_pdbx_reference_molecule_features.value
FAM_000252   PRD_000381   1     1     PubChem                External_reference_ID     11385053
FAM_000252   PRD_000381   2     1     ChemSpider             External_reference_ID     9559966
FAM_000252   PRD_000402   3     1     PubChem                External_reference_ID     10390162
FAM_000252   PRD_000402   4     1     ChemSpider             External_reference_ID     8565604
FAM_000252   PRD_000414   5     1     CAS                    External_reference_ID     65144-34-5
FAM_000252   PRD_000414   6     1     ChemSpider             External_reference_ID     4589024
#
loop_
_pdbx_family_prd_audit.family_prd_id
_pdbx_family_prd_audit.date
_pdbx_family_prd_audit.processing_site
_pdbx_family_prd_audit.action_type
FAM_000252	2012-02-08	RCSB	"Create family"	
FAM_000252	2013-10-16	RCSB	"Initial release"	
#
