data_FAM_000331
#
_pdbx_reference_molecule_family.family_prd_id   FAM_000331
_pdbx_reference_molecule_family.name            "VRPR-fluoromethyl ketone"
_pdbx_reference_molecule_family.release_status  REL
_pdbx_reference_molecule_family.replaces        ?
_pdbx_reference_molecule_family.replaced_by     ?
#
loop_
_pdbx_reference_molecule_list.family_prd_id
_pdbx_reference_molecule_list.prd_id
FAM_000331   PRD_001076  
#
loop_
_pdbx_reference_molecule_synonyms.family_prd_id
_pdbx_reference_molecule_synonyms.prd_id
_pdbx_reference_molecule_synonyms.ordinal
_pdbx_reference_molecule_synonyms.source
_pdbx_reference_molecule_synonyms.name
FAM_000331   PRD_001076   1     PDB          z-VRPR-fmk
FAM_000331   PRD_001076   2     enzolifesciences.com Z-Val-Arg-Pro-DL-Arg-FMK
FAM_000331   PRD_001076   3     enzolifesciences.com "MALT1 inhibitor"
FAM_000331   PRD_001076   4     enzolifesciences.com "Z VRPR FMK"
#
loop_
_pdbx_reference_molecule_annotation.family_prd_id
_pdbx_reference_molecule_annotation.prd_id
_pdbx_reference_molecule_annotation.ordinal
_pdbx_reference_molecule_annotation.source
_pdbx_reference_molecule_annotation.type
_pdbx_reference_molecule_annotation.text
FAM_000331   PRD_001076   1     PMID:22158899        Function                  "Inhibitor of Mucosa-associated lymphoid tissue lymphoma translocation protein 1, EC: 3.4.22.-"
FAM_000331   PRD_001076   2     enzolifesciences.com "Mechanism of action"     "The proteolytic activity of the paracaspase MALT1 is key to NF-kB and T cell activation. Z-VRPR-FMK is a selective MALT1 inhibitor of such proteolytic activity."
#
loop_
_pdbx_family_prd_audit.family_prd_id
_pdbx_family_prd_audit.date
_pdbx_family_prd_audit.processing_site
_pdbx_family_prd_audit.action_type
FAM_000331	2012-09-12	RCSB	"Create family"	
FAM_000331	2013-10-16	RCSB	"Initial release"	
#
