data_FAM_000241
#
_pdbx_reference_molecule_family.family_prd_id   FAM_000241
_pdbx_reference_molecule_family.name            "PPACK II"
_pdbx_reference_molecule_family.release_status  REL
_pdbx_reference_molecule_family.replaces        ?
_pdbx_reference_molecule_family.replaced_by     ?
#
loop_
_pdbx_reference_molecule_list.family_prd_id
_pdbx_reference_molecule_list.prd_id
FAM_000241   PRD_000369  
FAM_000241   PRD_001160  
#
loop_
_pdbx_reference_molecule_synonyms.family_prd_id
_pdbx_reference_molecule_synonyms.prd_id
_pdbx_reference_molecule_synonyms.ordinal
_pdbx_reference_molecule_synonyms.source
_pdbx_reference_molecule_synonyms.name
FAM_000241   PRD_000369   1     PDB          FFRCK
FAM_000241   PRD_000369   2     PDB          "PPACK II"
FAM_000241   PRD_000369   3     Scifinder    "L-Phenylalaninamide D-phenylalanyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-(chloroacetyl)butyl]-(9CI)"
FAM_000241   PRD_000369   4     Scifinder    "L-Phenylalaninamide D-phenylalanyl-N-[4-[(aminoiminomethyl)amino]-1-(chloroacetyl)butyl]-(S)-"
FAM_000241   PRD_000369   5     PubChem      Dppacmk
FAM_000241   PRD_000369   6     PubChem      Phe-phe-arg-CK
FAM_000241   PRD_000369   7     PubChem      FFRCK
FAM_000241   PRD_000369   8     PubChem      Phe-phe-arg-CH2-Cl
FAM_000241   PRD_000369   9     PubChem      D-Phe-phe-arg-CH2Cl
FAM_000241   PRD_000369   10    PubChem      "Phe-phe-arg-chloromethyl ketone"
FAM_000241   PRD_000369   11    PubChem      "D-Phe-phe-arg-chloromethyl ketone"
FAM_000241   PRD_000369   12    PubChem      "Phenylalanyl-phenylalanyl-arginine chloromethyl ketone"
FAM_000241   PRD_000369   13    ChemSpider   D-Phe-phe-arg-CH2Cl
FAM_000241   PRD_000369   14    ChemSpider   "D-Phe-phe-arg-chloromethyl ketone"
FAM_000241   PRD_000369   15    ChemSpider   "Dppacmkhe-arg-chloromethyl ketone"
FAM_000241   PRD_000369   16    ChemSpider   "FFRCKmkhe-arg-chloromethyl ketone"
FAM_000241   PRD_000369   17    ChemSpider   "Phe-phe-arg-CH2-Clromethyl ketone"
FAM_000241   PRD_000369   18    ChemSpider   "Phe-phe-arg-chloromethyl ketonene"
FAM_000241   PRD_000369   19    ChemSpider   "Phe-phe-arg-CKloromethyl ketonene"
FAM_000241   PRD_000369   20    eMolecules   "D-Phe-Phe-Arg Chloromethylketone"
FAM_000241   PRD_000369   21    InhibitorSourceBook "PPACK II"
#
loop_
_pdbx_reference_molecule_annotation.family_prd_id
_pdbx_reference_molecule_annotation.prd_id
_pdbx_reference_molecule_annotation.ordinal
_pdbx_reference_molecule_annotation.source
_pdbx_reference_molecule_annotation.type
_pdbx_reference_molecule_annotation.text
FAM_000241   PRD_000369   1     PubChem              Function                  "irreversible inhibitor of mammalian glandular kallikreins do not confuse with PPACK (Phe-Pro-Arg-CH2-Cl) or with Pro-Phe-Arg-CH2-Cl"
FAM_000241   PRD_000369   2     PubChem              "Pharmacological Action"  "Serine Proteinase Inhibitors, Cysteine Proteinase Inhibitors"
FAM_000241   PRD_001160   3     PMID:10523290        Function                  "inhibitor of gingipain R, EC: 3.4.22.37"
#
loop_
_pdbx_reference_molecule_features.family_prd_id
_pdbx_reference_molecule_features.prd_id
_pdbx_reference_molecule_features.ordinal
_pdbx_reference_molecule_features.source_ordinal
_pdbx_reference_molecule_features.source
_pdbx_reference_molecule_features.type
_pdbx_reference_molecule_features.value
FAM_000241   PRD_000369   1     1     MeSH                   MeSH_Unique_ID            C027587
FAM_000241   PRD_000369   2     1     PubChem                External_reference_ID     126484
FAM_000241   PRD_000369   3     2     PubChem                External_reference_ID     9806026
FAM_000241   PRD_000369   4     3     PubChem                External_reference_ID     115185
FAM_000241   PRD_000369   5     1     ChemSpider             External_reference_ID     112396
FAM_000241   PRD_000369   6     2     ChemSpider             External_reference_ID     7981786
FAM_000241   PRD_000369   7     3     ChemSpider             External_reference_ID     8454160
FAM_000241   PRD_000369   8     4     ChemSpider             External_reference_ID     19981380
FAM_000241   PRD_000369   9     5     ChemSpider             External_reference_ID     13651748
FAM_000241   PRD_000369   10    6     ChemSpider             External_reference_ID     103064
FAM_000241   PRD_000369   11    1     LeadScope              External_reference_ID     LS-176430
FAM_000241   PRD_000369   12    1     ChEBI                  External_reference_ID     586794
FAM_000241   PRD_000369   13    1     BindingDB              External_reference_ID     23569
FAM_000241   PRD_000369   14    1     InhibitorSourceBook    External_reference_ID     520219
FAM_000241   PRD_000369   15    1     CAS                    External_reference_ID     74392-49-7
FAM_000241   PRD_000369   16    1     MolPort                External_reference_ID     MolPort-003-847-033
FAM_000241   PRD_000369   17    1     ChemIDplus             External_reference_ID     074392497
FAM_000241   PRD_000369   18    2     ChemIDplus             External_reference_ID     065149237
FAM_000241   PRD_000369   19    1     eMolecules             URL                       http://www.emolecules.com/cgi-bin/more?vid=27519594
#
loop_
_pdbx_family_prd_audit.family_prd_id
_pdbx_family_prd_audit.date
_pdbx_family_prd_audit.processing_site
_pdbx_family_prd_audit.action_type
FAM_000241	2012-02-08	RCSB	"Create family"	
FAM_000241	2013-10-16	RCSB	"Initial release"	
#
