data_FAM_000191
#
_pdbx_reference_molecule_family.family_prd_id   FAM_000191
_pdbx_reference_molecule_family.name            "RIGID TRIPEPTIDYL ALDEHYDE INHIBITORS"
_pdbx_reference_molecule_family.release_status  REL
_pdbx_reference_molecule_family.replaces        ?
_pdbx_reference_molecule_family.replaced_by     ?
#
loop_
_pdbx_reference_molecule_list.family_prd_id
_pdbx_reference_molecule_list.prd_id
FAM_000191   PRD_000322  
FAM_000191   PRD_000324  
FAM_000191   PRD_000769  
#
loop_
_pdbx_reference_molecule_synonyms.family_prd_id
_pdbx_reference_molecule_synonyms.prd_id
_pdbx_reference_molecule_synonyms.ordinal
_pdbx_reference_molecule_synonyms.source
_pdbx_reference_molecule_synonyms.name
FAM_000191   PRD_000322   1     Scifinder    "1-Piperidineacetamide, N-[4-[(aminoiminomethyl)amino]-1-formylbutyl]-2-oxo-3-[[(phenylmethyl)sulfonyl]amino]-, [S-(R*,R*)]-"
FAM_000191   PRD_000322   2     Scifinder    "CVS 1578"
FAM_000191   PRD_000322   3     PubChem      N-((S)-1-Formyl-4-guanidino-butyl)-2-((S)-2-oxo-3-phenylmethanesulfonylamino-piperidin-1-yl)-acetamide
FAM_000191   PRD_000322   4     PubChem      2-[(3S)-3-(benzylsulfonylamino)-2-oxopiperidin-1-yl]-N-[(2S)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]acetamide
FAM_000191   PRD_000324   5     PDB          CVS1694
FAM_000191   PRD_000324   6     Scifinder    "Cyclo(L-alpha-aspartyl-L-tryptophyl-L-alpha-glutamyl-L-phenylalanyl-D-prolyl-L-prolyl-L-phenylalanyl-L-alpha-glutamyl-6-chloro-D-tryptophyl-L-leucyl) (9CI)"
FAM_000191   PRD_000324   7     PubChem
;N-[(S)-1-((R)-1-Carbamimidoyl-piperidin-3-ylmethyl)-2-oxo-ethyl]-2-((S)-2-oxo-3-phenylmethanesulfonylamino-piperidin-1-yl)-acetamide
;
FAM_000191   PRD_000324   8     PubChem
;2-[(3S)-3-(benzylsulfonylamino)-2-oxopiperidin-1-yl]-N-[(2S)-1-[(3R)-1-carbamimidoylpiperidin-3-yl]-3-oxopropan-2-yl]acetamide
;
#
loop_
_pdbx_reference_molecule_annotation.family_prd_id
_pdbx_reference_molecule_annotation.prd_id
_pdbx_reference_molecule_annotation.ordinal
_pdbx_reference_molecule_annotation.source
_pdbx_reference_molecule_annotation.type
_pdbx_reference_molecule_annotation.text
FAM_000191   PRD_000322   1     DOI:10.1016/S0960-894X(97)00446-0 Function                  "selective thrombin inhibitor"
FAM_000191   PRD_000324   2     PMID:9724521         Function                  "inhibitor of Thrombin, EC: 3.4.21.5"
FAM_000191   PRD_000324   3     PMID:9724521         Function                  "inhibitor or Trypsin, EC: 3.4.21.4"
FAM_000191   PRD_000769   4     PMID:9724521         Function                  "inhibitor of Thrombin, EC: 3.4.21.5"
FAM_000191   PRD_000769   5     PMID:9724521         Function                  "inhibitor or Trypsin, EC: 3.4.21.4"
#
loop_
_pdbx_reference_molecule_features.family_prd_id
_pdbx_reference_molecule_features.prd_id
_pdbx_reference_molecule_features.ordinal
_pdbx_reference_molecule_features.source_ordinal
_pdbx_reference_molecule_features.source
_pdbx_reference_molecule_features.type
_pdbx_reference_molecule_features.value
FAM_000191   PRD_000322   1     1     PubChem                External_reference_ID     9847373
FAM_000191   PRD_000322   2     1     ChEBI                  External_reference_ID     332443
FAM_000191   PRD_000322   3     1     ChemSpider             External_reference_ID     8023087
FAM_000191   PRD_000324   4     1     ChEBI                  External_reference_ID     332556
FAM_000191   PRD_000324   5     1     PubChem                External_reference_ID     10006399
FAM_000191   PRD_000324   6     1     ChemSpider             External_reference_ID     8181979
#
loop_
_pdbx_family_prd_audit.family_prd_id
_pdbx_family_prd_audit.date
_pdbx_family_prd_audit.processing_site
_pdbx_family_prd_audit.action_type
FAM_000191	2012-02-08	RCSB	"Create family"	
FAM_000191	2013-10-16	RCSB	"Initial release"	
#
