data_FAM_000360
#
_pdbx_reference_molecule_family.family_prd_id   FAM_000360
_pdbx_reference_molecule_family.name            "DP-P-DR-DT based inhibitors"
_pdbx_reference_molecule_family.release_status  REL
_pdbx_reference_molecule_family.replaces        ?
_pdbx_reference_molecule_family.replaced_by     ?
#
loop_
_pdbx_reference_molecule_list.family_prd_id
_pdbx_reference_molecule_list.prd_id
FAM_000360   PRD_000940  
FAM_000360   PRD_001092  
FAM_000360   PRD_001093  
#
loop_
_pdbx_reference_molecule_synonyms.family_prd_id
_pdbx_reference_molecule_synonyms.prd_id
_pdbx_reference_molecule_synonyms.ordinal
_pdbx_reference_molecule_synonyms.source
_pdbx_reference_molecule_synonyms.name
FAM_000360   PRD_000940   1     PDB          "D-Phe-Pro-D-Arg-D-Thr inhibitor"
FAM_000360   PRD_000940   2     PDB          fPRT
FAM_000360   PRD_001092   3     PDB          "D-Phe-Pro-D-Arg-Cys inhibitor"
FAM_000360   PRD_001092   4     PDB          fPRC
FAM_000360   PRD_001093   5     PDB          "D-Phe-Pro-D-Arg-Ile inhibitor"
FAM_000360   PRD_001093   6     PDB          fPRI
#
loop_
_pdbx_reference_molecule_annotation.family_prd_id
_pdbx_reference_molecule_annotation.prd_id
_pdbx_reference_molecule_annotation.ordinal
_pdbx_reference_molecule_annotation.source
_pdbx_reference_molecule_annotation.type
_pdbx_reference_molecule_annotation.text
FAM_000360   PRD_000940   1     PMID:22457833        Function                  "Inhibitor of Thrombin, EC: 3.4.21.5"
FAM_000360   PRD_001092   2     PMID:22457833        Function                  "Inhibitor of Thrombin, EC: 3.4.21.5"
FAM_000360   PRD_001093   3     PMID:22457833        Function                  "Inhibitor of Thrombin, EC: 3.4.21.5"
#
loop_
_pdbx_reference_molecule_features.family_prd_id
_pdbx_reference_molecule_features.prd_id
_pdbx_reference_molecule_features.ordinal
_pdbx_reference_molecule_features.source_ordinal
_pdbx_reference_molecule_features.source
_pdbx_reference_molecule_features.type
_pdbx_reference_molecule_features.value
FAM_000360   PRD_000940   1     1     BindingMoad            URL                       http://www.bindingmoad.org/pdbrecords/index/3U8O
FAM_000360   PRD_001092   2     1     BindingMoad            URL                       http://www.bindingmoad.org/pdbrecords/index/3U8T
FAM_000360   PRD_001093   3     1     BindingMoad            URL                       http://www.bindingmoad.org/pdbrecords/index/3U8R
#
_citation.id                       1
_citation.year                     2012
_citation.journal_volume           7
_citation.page_first               e34354
_citation.page_last                ?
_citation.pdbx_database_id_DOI     10.1371/journal.pone.0034354
_citation.pdbx_database_id_PubMed  22457833
_citation.title                    "Rational design and characterization of D-Phe-Pro-D-Arg-derived direct thrombin inhibitors"
_citation.journal_abbrev           "PLoS One"
#
loop_
_citation_author.citation_id
_citation_author.ordinal
_citation_author.name
1  1  "Figueiredo, A.C."  
1  2  "Clement, C.C."  
1  3  "Zakia, S."  
1  4  "Gingold, J."  
1  5  "Philipp, M."  
1  6  "Pereira, P.J."  
#
loop_
_pdbx_family_prd_audit.family_prd_id
_pdbx_family_prd_audit.date
_pdbx_family_prd_audit.processing_site
_pdbx_family_prd_audit.action_type
FAM_000360	2013-04-11	RCSB	"Create family"	
FAM_000360	2013-10-16	RCSB	"Initial release"	
#
