data_FAM_000210
#
_pdbx_reference_molecule_family.family_prd_id   FAM_000210
_pdbx_reference_molecule_family.name            VAD-fluoromethylketone
_pdbx_reference_molecule_family.release_status  REL
_pdbx_reference_molecule_family.replaces        ?
_pdbx_reference_molecule_family.replaced_by     ?
#
loop_
_pdbx_reference_molecule_list.family_prd_id
_pdbx_reference_molecule_list.prd_id
FAM_000210   PRD_000338  
FAM_000210   PRD_001082  
#
loop_
_pdbx_reference_molecule_synonyms.family_prd_id
_pdbx_reference_molecule_synonyms.prd_id
_pdbx_reference_molecule_synonyms.ordinal
_pdbx_reference_molecule_synonyms.source
_pdbx_reference_molecule_synonyms.name
FAM_000210   PRD_000338   1     PDB          Z-VAD-FMK
FAM_000210   PRD_000338   2     Scifinder    "L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[1-(carboxymethyl)-3-fluoro-2-oxopropyl]-, (S)-"
FAM_000210   PRD_000338   3     Beilstein    "z-Val-Ala-Asp-fluoromethyl ketone"
FAM_000210   PRD_000338   4     PubChem      z-vad-FMK
FAM_000210   PRD_000338   5     PubChem      "Caspase Inhibitor VI"
FAM_000210   PRD_000338   6     PubChem      Z-Val-Ala-Asp-FMK
FAM_000210   PRD_000338   7     PubChem      "Z-VAD-FMK, Non-methylated"
FAM_000210   PRD_000338   8     PubChem      FK109
FAM_000210   PRD_000338   9     ChemSpider   carbobenzyloxy-Val-Ala-Asp-alpha-fluoromethylketone
FAM_000210   PRD_000338   10    ChemSpider   "L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[1-(carboxymethyl)-3-fluoro-2-oxopropyl]-, (S)-"
FAM_000210   PRD_000338   11    ChemSpider   "L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[(1S)-1-(carboxymethyl)-3-fluoro-2-oxopropyl]-(9CI)"
FAM_000210   PRD_000338   12    ChemSpider   carbobenzyloxy-Val-Ala-Asp-alpha-fluoromethylketoneN-[(1S)-1-(carboxymethyl)-3-fluoro-2-oxopropyl]-(9CI)
FAM_000210   PRD_000338   13    ChemBank     Z-VAD-FMK
FAM_000210   PRD_000338   14    ChemBank     Z-val-ala-asp(Ome)-fluoromethylketone
FAM_000210   PRD_000338   15    ChemBank     Z-Val-Ala-Asp-fluoromethylketone
FAM_000210   PRD_000338   16    ChemBank     ZVAD-fluoromethylketone
FAM_000210   PRD_000338   17    ChemBank     ZVAD-FMK
FAM_000210   PRD_000338   18    ChemBank     zVAD-fmk
FAM_000210   PRD_000338   19    ChemBank     ZVAD-FMK
FAM_000210   PRD_000338   20    ChemBank     zVAD.fmk
FAM_000210   PRD_000338   21    InhibitorSourceBook "Caspase Inhibitor VI"
FAM_000210   PRD_000338   22    PubChem      AC1NUZLX
FAM_000210   PRD_001082   23    PDB          Z-VAE(OMe)-FMK
FAM_000210   PRD_001082   24    PDB          VAEFMK
FAM_000210   PRD_001082   25    PubChem      AC1NUZMF
FAM_000210   PRD_001082   26    PubChem      "L-alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[(1S)-1-(fluoroacetyl)-4-methoxy-4-oxobutyl]-methyl (4S)-6-fluoro-4-[[(2S)-2-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]propanoyl]amino]-5-oxohexanoate"
#
loop_
_pdbx_reference_molecule_annotation.family_prd_id
_pdbx_reference_molecule_annotation.prd_id
_pdbx_reference_molecule_annotation.ordinal
_pdbx_reference_molecule_annotation.source
_pdbx_reference_molecule_annotation.type
_pdbx_reference_molecule_annotation.text
FAM_000210   PRD_000338   1     InhibitorSourceBook  Function                  "irreversible caspase inhibitor, useful in studies involving recombinant, isolated, and purified caspase enzymes"
FAM_000210   PRD_000338   2     PMID:16500903        Function                  "Inhibitor of PEPTIDE N-GLYCANASE, EC: 3.5.1.52"
FAM_000210   PRD_000338   3     PMID:15610852        Function                  "pan-caspase inhibitor, and irreversible inhibitor of yeast and mammalian PNGase"
FAM_000210   PRD_001082   4     PMID:22617491        Function                  "inhibitor of ubiquitin carboxy-terminal hydrolase L1, EC: 3.4.19.12"
FAM_000210   PRD_000338   5     PubChem              "Pharmacological action"  "Cysteine Proteinase Inhibitors"
FAM_000210   PRD_000338   6     PubChem              "Pharmacological action"  "Neuroprotective Agents"
#
loop_
_pdbx_reference_molecule_features.family_prd_id
_pdbx_reference_molecule_features.prd_id
_pdbx_reference_molecule_features.ordinal
_pdbx_reference_molecule_features.source_ordinal
_pdbx_reference_molecule_features.source
_pdbx_reference_molecule_features.type
_pdbx_reference_molecule_features.value
FAM_000210   PRD_000338   1     1     MeSH                   MeSH_Unique_ID            C096713
FAM_000210   PRD_000338   2     1     Beilstein              External_reference_ID     8949493
FAM_000210   PRD_000338   3     1     PubChem                External_reference_ID     5497171
FAM_000210   PRD_000338   4     1     ChemSpider             External_reference_ID     4593739
FAM_000210   PRD_000338   5     1     ChemDB                 External_reference_ID     9750068
FAM_000210   PRD_000338   6     1     InhibitorSourceBook    External_reference_ID     219007
FAM_000210   PRD_000338   7     1     CAS                    External_reference_ID     161401-82-7
FAM_000210   PRD_000338   8     2     InhibitorSourceBook    External_reference_ID     219011
FAM_000210   PRD_000338   9     1     BIND                   External_reference_ID     1944
FAM_000210   PRD_000338   10    1     ChEBI                  External_reference_ID     441465
FAM_000210   PRD_001082   11    1     PubChem                External_reference_ID     5497177
FAM_000210   PRD_001082   12    1     ChemSpider             External_reference_ID     4593745
FAM_000210   PRD_001082   13    1     BIND                   External_reference_ID     1950
#
loop_
_pdbx_family_prd_audit.family_prd_id
_pdbx_family_prd_audit.date
_pdbx_family_prd_audit.processing_site
_pdbx_family_prd_audit.action_type
FAM_000210	2012-02-08	RCSB	"Create family"	
FAM_000210	2013-10-16	RCSB	"Initial release"	
#
