data_FAM_000150
#
_pdbx_reference_molecule_family.family_prd_id   FAM_000150
_pdbx_reference_molecule_family.name            "DEVD-chloromethyl ketone inhibitors"
_pdbx_reference_molecule_family.release_status  REL
_pdbx_reference_molecule_family.replaces        ?
_pdbx_reference_molecule_family.replaced_by     ?
#
loop_
_pdbx_reference_molecule_list.family_prd_id
_pdbx_reference_molecule_list.prd_id
FAM_000150   PRD_000277  
FAM_000150   PRD_000295  
FAM_000150   PRD_000238  
FAM_000150   PRD_000924  
#
loop_
_pdbx_reference_molecule_synonyms.family_prd_id
_pdbx_reference_molecule_synonyms.prd_id
_pdbx_reference_molecule_synonyms.ordinal
_pdbx_reference_molecule_synonyms.source
_pdbx_reference_molecule_synonyms.name
FAM_000150   PRD_000277   1     Scifinder
;L-Valinamide, N-[(phenylmethoxy)carbonyl]-L-alpha-aspartyl-L-alpha-glutamyl-N-[(1S)-1-(carboxymethyl)-3-chloro-2-oxopropyl]-(9CI)
;
FAM_000150   PRD_000277   2     Beilstein    Z-DEVD-CMK
FAM_000150   PRD_000238   3     PDB          Ac-DEVD-cmk
FAM_000150   PRD_000238   4     Scifinder    "L-Valinamide, N-acetyl-L-alpha-aspartyl-L-alpha-glutamyl-N-[(1S)-1-(carboxymethyl)-3-chloro-2-oxopropyl]-"
FAM_000150   PRD_000238   5     PubChem      Ac-DEVD-CMK
FAM_000150   PRD_000238   6     PubChem      "Caspase-3 Inhibitor III"
FAM_000150   PRD_000238   7     InhibitorSourceBook "Caspase-3 Inhibitor III"
FAM_000150   PRD_000924   8     PDB          Z-EVD-dcbmk
FAM_000150   PRD_000924   9     PDB          "TRIPEPTIDE KETONE INHIBITOR ZEVD-DCBMK"
#
loop_
_pdbx_reference_molecule_annotation.family_prd_id
_pdbx_reference_molecule_annotation.prd_id
_pdbx_reference_molecule_annotation.ordinal
_pdbx_reference_molecule_annotation.source
_pdbx_reference_molecule_annotation.type
_pdbx_reference_molecule_annotation.text
FAM_000150   PRD_000295   1     PMID:11734640        Function                  "protease caspase 9 inhibitor"
FAM_000150   PRD_000295   2     PMID:10508784        Function                  "caspase 8 inhibitor"
FAM_000150   PRD_000277   3     PMID:16787777        Function                  "CASPASE-3 Inhibitor"
FAM_000150   PRD_000238   4     InhibitorSourceBook  Function                  "cell-permeable and irreversible inhibitor of caspase-3"
FAM_000150   PRD_000238   5     Calbiochem           Function                  "A potent, cell-permeable, and irreversible inhibitor of caspase-3 as well as caspase-6, caspase-7, caspase-8, and caspase-10"
FAM_000150   PRD_000924   6     PMID:23650375        Function                  "inhibitor of Procaspase 7, EC: 3.4.22.60"
#
loop_
_pdbx_reference_molecule_features.family_prd_id
_pdbx_reference_molecule_features.prd_id
_pdbx_reference_molecule_features.ordinal
_pdbx_reference_molecule_features.source_ordinal
_pdbx_reference_molecule_features.source
_pdbx_reference_molecule_features.type
_pdbx_reference_molecule_features.value
FAM_000150   PRD_000277   1     1     PubChem                External_reference_ID     9895697
FAM_000150   PRD_000277   2     1     ChemSpider             External_reference_ID     8071362
FAM_000150   PRD_000238   3     1     PubChem                External_reference_ID     9959259
FAM_000150   PRD_000238   4     1     ChemSpider             External_reference_ID     8134868
FAM_000150   PRD_000238   5     1     InhibitorSourceBook    External_reference_ID     218750
FAM_000150   PRD_000238   6     1     CAS                    External_reference_ID     285570-60-7
FAM_000150   PRD_000238   7     1     Calbiochem             External_reference_ID     218750
FAM_000150   PRD_000238   8     1     Calbiochem             Image                     http://structuresearch.merck-chemicals.com/cgi-bin/getStructureImage.pl?owner=EMD&unit=BIO&product=218750
FAM_000150   PRD_000238   9     2     PubChem                External_reference_ID     11963556
FAM_000150   PRD_000238   10    2     ChemSpider             External_reference_ID     10137724
#
loop_
_pdbx_family_prd_audit.family_prd_id
_pdbx_family_prd_audit.date
_pdbx_family_prd_audit.processing_site
_pdbx_family_prd_audit.action_type
FAM_000150	2012-02-08	RCSB	"Create family"	
FAM_000150	2013-10-16	RCSB	"Initial release"	
#
