2024-10-23 REL PDBe PDBe PDBe 2020-04-10 2020-09-09 2020-09-09 2024-10-23 Swedish Research Council 2014-4116 Sweden Swedish Research Council 2018-03694 Sweden Knut and Alice Wallenberg Foundation 2017.0091 Sweden Knut and Alice Wallenberg Foundation 2013.0006 Sweden Cytochrome c oxidase from Saccharomyces cerevisiae Berndtsson J Rathore S Ott M CIV, CytcO, ELECTRON TRANSPORT Berndtsson J Aufschnaiter A Rathore S Marin-Buera L Dawitz H Diessl J Kohler V Barrientos A Buttner S Fontanesi F Ott M Respiratory supercomplexes enhance electron transport by decreasing cytochrome c diffusion distance. Embo Rep. UK 21 e51015 e51015 2020 33016568 doi:10.15252/embr.202051015 1469-3178 6ymy FULLOVERLAP Cytochrome c oxidase Cytochrome c oxidase 0 1 2 3 4 5 6 7 8 9 10 11 12 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) W303-1b Mitochondria Cytochrome c oxidase subunit 1 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 0.058316938 1 LEVO WLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHGNSQLFNVLVVGHAVLMIFFLVMPALIGGFGNYLL PLMIGATDTAFPRINNIAFWVLPMGLVCLVTSTLVESGAGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAIN FIVTTLNMRTNGMTMHKLPLFVWSIFITAFLLLLSLPVLSAGITMLLLDRNFNTSFFEVSGGGDPILYEHLFWFFGHPEV YILIIPGFGIISHVVSTYSKKPVFGEISMVYAMASIGLLGFLVWSHHMYIVGLDADTRAYFTSATMIIAIPTGIKIFSWL ATIHGGSIRLATPMLYAIAFLFLFTMGGLTGVALANASLDVAFHDTYYVVGHFHYVLSMGAIFSLFAGYYYWSPQILGLN YNEKLAQIQFWLIFIGANVIFFPMHFLGINGMPRRIPDYPDAFAGWNYVASIGSFIATLSLFLFIYILYDQLVNGLNNKV NNKSVIYNKAPDFVESNTIFNLNTVKSSSIEFLLTSPPAVHSFNTPAVQS P00401 1.9.3.1 Cytochrome c oxidase subunit 2 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 0.026779815999999998 1 LEVO DVPTPYACYFQDSATPNQEGILELHDNIMFYLLVILGLVSWMLYTIVMTYSKNPIAYKYIKHGQTIEVIWTIFPAVILLI IAFPSFILLYLCDEVISPAMTIKAIGYQWYWKYEYSDFINDSGETVEFESYVIPDELLEEGQLRLLDTDTSMVVPVDTHI RFVVTAADVIHDFAIPSLGIKVDATPGRLNQVSALIQREGVFYGACSELCGTGHANMPIKIEAVSLPKFLEWLNEQ P00410 1.9.3.1 Cytochrome c oxidase subunit 3 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 0.030252390999999997 1 LEVO THLERSRHQQHPFHMVMPSPWPIVVSFALLSLALSTALTMHGYIGNMNMVYLALFVLLTSSILWFRDIVAEATYLGDHTM AVRKGINLGFLMFVLSEVLIFAGLFWAYFHSAMSPDVTLGACWPPVGIEAVQPTELPLLNTIILLSSGATVTYSHHALIA GNRNKALSGLLITFWLIVIFVTCQYIEYTNAAFTISDGVYGSVFYAGTGLHFLHMVMLAAMLGVNYWRMRNYHLTAGHHV GYETTIIYTHVLDVIWLFLYVVFYWWGV P00420 1.9.3.1 Cytochrome c oxidase subunit 4, mitochondrial Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 0.012694381999999999 1 LEVO VVKTAQNLAEVNGPETLIGPGAKEGTVPTDLDQETGLARLELLGKLEGIDVFDTKPLDSSRKGTMKDPIIIESYDDYRYV GCTGSPAGSHTIMWLKPTVNEVARCWECGSVYKLNPV P04037 Cytochrome c oxidase subunit 5A, mitochondrial Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 0.014324147 1 LEVO ALSNAAVMDLQSRWENMPSTEQQDIVSKLSERQKLPWAQLTEPEKQAVWYISYGEWGPRRPVLNKGDSSFIAKGVAAGLL FSVGLFAVVRMAGGQDAKTMNKEWQLKSDEYLKSKNANPWGGYSQVQS P00424 Cytochrome c oxidase subunit 6, mitochondrial Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 0.011725173 1 LEVO ETFEEFTARYEKEFDEAYDLFEVQRVLNNCFSYDLVPAPAVIEKALRAARRVNDLPTAIRVFEALKYKVENEDQYKAYLD ELKDVRQELGVPLKEELFP P00427 Cytochrome c oxidase subunit 7, mitochondrial Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 0.006410639 1 LEVO NKVIQLQKIFQSSTKPLWWRHPRSALYLYPFYAIFAVAVVTPLLYIPNAIRGIKA P10174 Cytochrome c oxidase subunit 8, mitochondrial Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 0.005737734999999999 1 LEVO VHFKDGVYENIPFKVKGRKTPYALSHFGFFAIGFAVPFVACYVQLKKSGAF P04039 Cytochrome c oxidase subunit 9, mitochondrial Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 0.006056131 1 LEVO TIAPITGTIKRRVIMDIVLGFSLGGVMASYWWWGFHMDKINKREKFYAELAE P07255 Cytochrome c oxidase subunit 12, mitochondrial Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 0.009225290999999998 1 LEVO NSPLHTVGFDARFPQQNQTKHCWQSYVDYHKCVNMKGEDFAPCKVFWKTYNALCPLDWIEKWDDQREKGIFAGDINSD Q01519 Cytochrome c oxidase subunit 13, mitochondrial Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 0.013306061 1 LEVO NALKPAFGPPDKVAAQKFKESLMATEKHAKDTSNMWVKISVWVALPAIALTAVNTYFVEKEHAEHREHLKHVPDSEWPRD YEFMNIRSKPFFWGDGDKTLFWNPVVNRHIEHDD P32799 Cytochrome c oxidase subunit 26, mitochondrial Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 0.004347023 1 LEVO ESWVITEGRRLIPEIFQWSAVLSVCLGWPGAVYFFSKA Q2V2P9 COPPER (II) ION 6.354599999999999e-05 1 CU HEME-A 0.000852837 2 HEA PHOSPHATIDYLETHANOLAMINE 0.0007340389999999999 7 PTY (2R,5S,11R,14R)-5,8,11-trihydroxy-2-(nonanoyloxy)-5,11-dioxido-16-oxo-14-[(propanoyloxy)methyl]-4,6,10,12,15-pentaoxa-5,11-diphosphanonadec-1-yl undecanoate 0.0008348619999999999 1 CN3 DINUCLEAR COPPER ION 0.00012709199999999998 1 CUA 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE 0.0007340389999999999 3 PCF ZINC ION 6.5409e-05 1 ZN singleParticle particle 7.4 10.0 C4H11NO3 Tris 150.0 NaCl Sodium chloride 0.1 C56H92O29 Digitonin 1.0 C7H7FO2S phenylmethylsulfonyl fluoride Homemade COPPER 400 CARBON LACEY GLOW DISCHARGE AIR ETHANE 100 277.15 FEI VITROBOT MARK IV FEI TITAN KRIOS FLOOD BEAM BRIGHT FIELD FIELD EMISSION GUN 300 70.0 2.7 -0.0014 -0.003 130000.0 FEI TITAN KRIOS AUTOGRID HOLDER GIF Bioquantum 20 GATAN K2 SUMMIT (4k x 4k) COUNTING 3838 3710 8775 9.0 40.0 1 647805
ab initio
 1 3.41 FSC 0.143 CUT-OFF cryoSPARC 2 201223 OTHER cryoSPARC 2
SGD
 MAXIMUM LIKELIHOOD cryoSPARC 2 cryoSPARC 2 emd_10848.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 370 370 370 0 0 0 370 370 370 392.2 392.2 392.2 90.0 90.0 90.0 X Y Z -1.2105628 2.4105902 0.004612802 0.058248185 1.0600001 1.0600001 1.0600001 0.41 AUTHOR emd_10848_msk_1.map emd_10848_half_map_1.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 370 370 370 0 0 0 370 370 370 392.2 392.2 392.2 90.0 90.0 90.0 X Y Z -0.46024767 1.5636891 0.00295922 0.058139987 1.0600001 1.0600001 1.0600001 AUTHOR Second half map emd_10848_half_map_2.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 370 370 370 0 0 0 370 370 370 392.2 392.2 392.2 90.0 90.0 90.0 X Y Z -0.476254 1.5595617 0.0029383143 0.058079734 1.0600001 1.0600001 1.0600001 AUTHOR Fist half map