<?xml version="1.0" encoding="UTF-8"?>
<emd xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:noNamespaceSchemaLocation="https://ftp.ebi.ac.uk/pub/databases/em_ebi/emdb_related/emdb-schemas/emdb_schemas/v3/v3_0_9_3/emdb.xsd" version="3.0.9.3" emdb_id="EMD-10768">
    <admin>
        <current_status>
            <date>2024-05-22</date>
            <code>REL</code>
            <processing_site>PDBe</processing_site>
        </current_status>
        <sites>
            <deposition>PDBe</deposition>
            <last_processing>PDBe</last_processing>
        </sites>
        <key_dates>
            <deposition>2020-03-16</deposition>
            <header_release>2021-03-10</header_release>
            <map_release>2021-03-10</map_release>
            <update>2024-05-22</update>
        </key_dates>
        <grant_support>
            <grant_reference>
                <funding_body>Spanish Ministry of Science, Innovation, and Universities</funding_body>
                <code>BFU-2016-74868P</code>
                <country>Spain</country>
            </grant_reference>
            <grant_reference>
                <funding_body>Spanish Ministry of Science, Innovation, and Universities</funding_body>
                <code>BIO2016-76400-R</code>
                <country>Spain</country>
            </grant_reference>
            <grant_reference>
                <funding_body>European Commission</funding_body>
                <code>inext-1750</code>
                <country>European Union</country>
            </grant_reference>
        </grant_support>
        <title>HAdV-F41 Capsid</title>
        <authors_list>
            <author>Perez Illana M</author>
            <author>Martinez M</author>
        </authors_list>
        <keywords>Adenovirus, VIRUS</keywords>
    </admin>
    <crossreferences>
        <citation_list>
            <primary_citation>
                <journal_citation published="true">
                    <author order="1">Perez-Illana M</author>
                    <author order="2">Martinez M</author>
                    <author order="3">Condezo GN</author>
                    <author order="4">Hernando-Perez M</author>
                    <author order="5">Mangroo C</author>
                    <author order="6">Brown M</author>
                    <author order="7">Marabini R</author>
                    <author order="8">San Martin C</author>
                    <title>Cryo-EM structure of enteric adenovirus HAdV-F41 highlights structural variations among human adenoviruses.</title>
                    <journal_abbreviation>Sci Adv</journal_abbreviation>
                    <country>US</country>
                    <volume>7</volume>
                    <year>2021</year>
                    <external_references type="PUBMED">33627423</external_references>
                    <external_references type="DOI">doi:10.1126/sciadv.abd9421</external_references>
                    <external_references type="ISSN">2375-2548</external_references>
                </journal_citation>
            </primary_citation>
        </citation_list>
        <pdb_list>
            <pdb_reference>
                <pdb_id>6yba</pdb_id>
                <relationship>
                    <in_frame>FULLOVERLAP</in_frame>
                </relationship>
            </pdb_reference>
        </pdb_list>
    </crossreferences>
    <sample>
        <name>Human adenovirus 41</name>
        <supramolecule_list>
            <virus_supramolecule supramolecule_id="1">
                <name>Human adenovirus 41</name>
                <parent>0</parent>
                <macromolecule_list>
                    <macromolecule>
                        <macromolecule_id>1</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>2</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>3</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>4</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>5</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>6</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>7</macromolecule_id>
                    </macromolecule>
                </macromolecule_list>
                <sci_species_name ncbi="10524">Human adenovirus 41</sci_species_name>
                <natural_host database="NCBI">
                    <organism ncbi="9606">Homo sapiens</organism>
                </natural_host>
                <virus_shell shell_id="1">
                    <diameter units="Å">840.0</diameter>
                </virus_shell>
                <virus_type>VIRION</virus_type>
                <virus_isolate>SEROTYPE</virus_isolate>
                <virus_enveloped>false</virus_enveloped>
                <virus_empty>false</virus_empty>
            </virus_supramolecule>
        </supramolecule_list>
        <macromolecule_list>
            <protein_or_peptide macromolecule_id="1">
                <name>Hexon protein</name>
                <natural_source database="NCBI">
                    <organism ncbi="10524">Human adenovirus F serotype 41</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.10406423399999999</theoretical>
                </molecular_weight>
                <number_of_copies>12</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MATPSMMPQWSYMHIAGQDASEYLSPGLVQFARATDTYFSLGNKFRNPTVAPTHDVTTDRSQRLTLRFVPVDREDTAYSY
KVRFTLAVGDNRVLDMASTYFDIRGVLDRGPSFKPYSGTAYNSLAPKTAPNPCEWKDNNKIKVRGQAPFIGTNINKDNGI
QIGTDTTNQPIYADKTYQPEPQVGQTQWNSEVGAAQKVAGRVLKDTTPMLPCYGSYAKPTNEKGGQASLITNGTDQTLTS
DVNLQFFALPSTPNEPKAVLYAENVSIEAPDTHLVYKPDVAQGTISSADLLTQQAAPNRPNYIGFRDNFIGLMYYNSTGN
MGVLAGQASQLNAVVDLQDRNTELSYQLMLDALGDRSRYFSMWNQAVDSYDPDVRIIENHGVEDELPNYCFPLGGSAATD
TYSGIKANGQTWTADDNYADRGAEIESGNIFAMEINLAANLWRSFLYSNVALYLPDSYKITPDNITLPENKNTYAYMNGR
VAVPSALDTYVNIGARWSPDPMDNVNPFNHHRNAGLRYRSMLLGNGRYVPFHIQVPQKFFAIKNLLLLPGSYTYEWNFRK
DVNMILQSSLGNDLRVDGASVRFDSINLYANFFPMAHNTASTLEAMLRNDTNDQSFNDYLCAANMLYPIPSNATSVPISI
PSRNWAAFRGWSFTRLKTKETPSLGSGFDPYFTYSGSVPYLDGTFYLNHTFKKVSIMFDSSVSWPGNDRLLTPNEFEIKR
TVDGEGYNVAQCNMTKDWFLIQMLSHYNIGYQGFYVPESYKDRMYSFFRNFQPMSRQVVNTTTYKEYQNVTLPFQHNNSG
FVGYMGPTMREGQAYPANYPYPLIGQTAVPSLTQKKFLCDRTMWRIPFSSNFMSMGALTDLGQNMLYANSAHALDMTFEV
DPMDEPTLLYVLFEVFDVVRIHQPHRGVIEAVYLRTPFSAGNATT</string>
                    <external_references type="UNIPROTKB">B2ZX09</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="2">
                <name>Penton protein</name>
                <natural_source database="NCBI">
                    <organism ncbi="10524">Human adenovirus F serotype 41</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.057142160000000004</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MRRAVGVPPVMAYAEGPPPSYESVMGSADSPATLEALYVPPRYLGPTEGRNSIRYSELAPLYDTTRVYLVDNKSADIASL
NYQNDHSNFQTTVVQNNDFTPAEAGTQTINFDERSRWGADLKTILRTNMPNINEFMSTNKFKARLMVEKKNKETGLPRYE
WFEFTLPEGNYSETMTIDLMNNAIVDNYLEVGRQNGVLESDIGVKFDTRNFRLGWDPVTKLVMPGVYTNEAFHPDIVLLP
GCGVDFTQSRLSNLLGIRKRLPFQEGFQIMYEDLEGGNIPALLDVAKYEASIQKAKEEGKEIGDDTFATRPQDLVIEPVA
KDSKNRSYNLLPNDQNNTAYRSWFLAYNYGDPKKGVQSWTLLTTADVTCGSQQVYWSLPDMMQDPVTFRPSTQVSNYPVV
GVELLPVHAKSFYNEQAVYSQLIRQSTALTHVFNRFPENQILVRPPAPTITTVSENVPALTDHGTLPLRSSISGVQRVTI
TDARRRTCPYVHKALGIVAPKVLSSRTF</string>
                    <external_references type="UNIPROTKB">Q9QAH8</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="3">
                <name>Pre-hexon-linking protein IIIa</name>
                <natural_source database="NCBI">
                    <organism ncbi="10524">Human adenovirus F serotype 41</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.064825246</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MQRSTAVVDGSQQVDPAMLAALQSQPSGVTPSDDWAAAMDRILALTTRNPEAFRQQPQANRFSAILEAVVPSRTNPTHEK
VLAIVNALTESKAIRKDEAGLIYNALLERVARYNSTNVQANLDRLTTDVREAVAQRERFMHDTNLGSQVALNAFLSTLPA
NVPRGQEDYVSFISALRLLVAEVPQSEVYQSGPDYFFQTSRQGLQTVNLTQAFKNLQGMWGVRAPVGDRATISSLLTPNT
RLLLLLIAPFTNSSTISRDSYLGHLITLYREAIGQTQVDEQTFQEITSVSRALGQQDTGSLEATLNFLLTNRQQKIPSQF
TLSTEEERILRYVQQSVSLYLMREGMTPSSALDMTARNMEPSLYSSNRPFINRLMDYLHRAAAMNSEYFTNAILNPHWMP
PSGFYTGEFDMPEGDDGFLWDDVSDSIFVPARYRKKEGGDELPLPLVEAASRGQSPFPSLPSLVSSSNSGRVLRPRLPGE
TDYLNDPLLQPVRNKNFPNNGVESLVDKMNRWKTYAQEQREWEESQSRPLAGPFSRWRRREDDQDDSADDNSVLDLGGTG
ASSNPFAHLRPQGRLGRLY</string>
                    <external_references type="UNIPROTKB">Q67716</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="4">
                <name>Pre-hexon-linking protein VIII</name>
                <natural_source database="NCBI">
                    <organism ncbi="10524">Human adenovirus F serotype 41</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.025358287</theoretical>
                </molecular_weight>
                <number_of_copies>2</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MSKEIPTPYMWSYQPQMGLAAGASQDYSSRMNWLSAGPHMIGRVNGIRATRNQILLEQAALTSTPRSQLNPPNWPAVQVY
QENPAPTTVLLPRDAEAEVQMTNSGAQLAGGSRHVRFRGRSSPYSPGPIKRLIIRGRGIQLNDEVVSSLTGLRPDGVFQL
GGAGRSSFTPRQAYLTLQSSSSQPRSGGIGTLQFVEEFVPSVYFNPFSGAPGLYPDDFIPNYDAVSESVDGYD</string>
                    <external_references type="UNIPROTKB">B5SNS9</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="5">
                <name>Hexon-interlacing protein</name>
                <natural_source database="NCBI">
                    <organism ncbi="10524">Human adenovirus F serotype 41</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.013617179</theoretical>
                </molecular_weight>
                <number_of_copies>4</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MSGSMEGNAVSFKGGVFSPYLTTRLPAWAGVRQNVMGSNVDGRPVAPANSATLTYATVGSSVDTAAAAAASAAASTARGM
AADFGLYNQLAASRSLREEDALSVVLTRLEELSQQLQDLFAKVALLNPPANAS</string>
                    <external_references type="UNIPROTKB">B5SNR3</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="6">
                <name>Pre-protein VI</name>
                <natural_source database="NCBI">
                    <organism ncbi="10524">Human adenovirus F serotype 41</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.029170144999999998</theoretical>
                </molecular_weight>
                <number_of_copies>4</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MEDINFASLAPRHGSRPFMGTWNEIGTSQLNGGAFSWSSLWSGIKNFGSSIKSFGNKAWNSNTGQMLRDKLKDQNFQQKV
VDGLASGINGVVDIANQALQNQINQRLENSRQPPVALKQRPTPEPEEVEVEEKLPPLETAPPLPSKGEKRPRPELEETLV
VESREPPSYEQALKEGASYPMTRPIGSMARPVYGKEKTPVTLELPPPAPTVPPMPTPTLGTNVPRLAAPTVAVATPARRV
RGANWQSTLNSIVGLGVKSLKRRRCY</string>
                    <external_references type="UNIPROTKB">B5SNS4</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="7">
                <name>Pre-histone-like nucleoprotein</name>
                <natural_source database="NCBI">
                    <organism ncbi="10524">Human adenovirus F serotype 41</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.020386445</theoretical>
                </molecular_weight>
                <number_of_copies>2</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MSILISPDNNTGWGLHSAGMYGGAKRRSSQHPVRVRGHYRAPWGAHTRGIISGRTTVDDVIDSVVADARRYQRPTSTVDS
VIDSVVADARRYAQRKSRLRRRRRRPTTAMIAARAVLRRARRIGRRAMRRAAAAASAGRARRQAARQAAAAIASMAQPRR
GNVYWVRDASGVRVPVRTRPPRS</string>
                    <external_references type="UNIPROTKB">B5SNS1</external_references>
                </sequence>
            </protein_or_peptide>
        </macromolecule_list>
    </sample>
    <structure_determination_list>
        <structure_determination structure_determination_id="1">
            <method>singleParticle</method>
            <aggregation_state>particle</aggregation_state>
            <specimen_preparation_list>
                <single_particle_preparation preparation_id="1">
                    <buffer>
                        <ph>7.4</ph>
                    </buffer>
                    <vitrification>
                        <cryogen_name>ETHANE</cryogen_name>
                    </vitrification>
                </single_particle_preparation>
            </specimen_preparation_list>
            <microscopy_list>
                <single_particle_microscopy microscopy_id="1">
                    <microscope>FEI TITAN KRIOS</microscope>
                    <illumination_mode>FLOOD BEAM</illumination_mode>
                    <imaging_mode>BRIGHT FIELD</imaging_mode>
                    <electron_source>FIELD EMISSION GUN</electron_source>
                    <acceleration_voltage units="kV">300</acceleration_voltage>
                    <image_recording_list>
                        <image_recording image_recording_id="1">
                            <film_or_detector_model>FEI FALCON III (4k x 4k)</film_or_detector_model>
                            <average_electron_dose_per_image units="e/Å^2">42.0</average_electron_dose_per_image>
                        </image_recording>
                    </image_recording_list>
                </single_particle_microscopy>
            </microscopy_list>
            <singleparticle_processing image_processing_id="1">
                <image_recording_id>1</image_recording_id>
                <startup_model type_of_model="EMDB MAP">
                    <emdb_id>EMD-4551</emdb_id>
                </startup_model>
                <final_reconstruction>
                    <applied_symmetry>
                        <point_group>I</point_group>
                    </applied_symmetry>
                    <resolution units="Å" res_type="BY AUTHOR">4.0</resolution>
                    <resolution_method>FSC 0.143 CUT-OFF</resolution_method>
                    <number_images_used>9926</number_images_used>
                </final_reconstruction>
                <initial_angle_assignment>
                    <type>MAXIMUM LIKELIHOOD</type>
                </initial_angle_assignment>
                <final_angle_assignment>
                    <type>MAXIMUM LIKELIHOOD</type>
                </final_angle_assignment>
            </singleparticle_processing>
        </structure_determination>
    </structure_determination_list>
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        <file>emd_10768.map.gz</file>
        <symmetry>
            <space_group>1</space_group>
        </symmetry>
        <data_type>IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES)</data_type>
        <dimensions>
            <col>780</col>
            <row>780</row>
            <sec>780</sec>
        </dimensions>
        <origin>
            <col>-390</col>
            <row>-390</row>
            <sec>-390</sec>
        </origin>
        <spacing>
            <x>780</x>
            <y>780</y>
            <z>780</z>
        </spacing>
        <cell>
            <a units="Å">1060.8</a>
            <b units="Å">1060.8</b>
            <c units="Å">1060.8</c>
            <alpha units="deg">90.0</alpha>
            <beta units="deg">90.0</beta>
            <gamma units="deg">90.0</gamma>
        </cell>
        <axis_order>
            <fast>X</fast>
            <medium>Y</medium>
            <slow>Z</slow>
        </axis_order>
        <statistics>
            <minimum>-0.25254947</minimum>
            <maximum>0.36396697</maximum>
            <average>0.0013525777</average>
            <std>0.027217593</std>
        </statistics>
        <pixel_spacing>
            <x units="Å">1.36</x>
            <y units="Å">1.36</y>
            <z units="Å">1.36</z>
        </pixel_spacing>
        <contour_list>
            <contour primary="true">
                <level>0.07</level>
                <source>AUTHOR</source>
            </contour>
        </contour_list>
        <label>::::EMDATABANK.org::::EMD-10768::::</label>
        <annotation_details>cryo_EM reconstruction</annotation_details>
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