<?xml version="1.0" encoding="UTF-8"?>
<emd xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:noNamespaceSchemaLocation="https://ftp.ebi.ac.uk/pub/databases/em_ebi/emdb_related/emdb-schemas/emdb_schemas/v3/v3_0_9_3/emdb.xsd" version="3.0.9.3" emdb_id="EMD-10711">
    <admin>
        <current_status>
            <date>2024-10-16</date>
            <code>REL</code>
            <processing_site>PDBe</processing_site>
        </current_status>
        <sites>
            <deposition>PDBe</deposition>
            <last_processing>PDBe</last_processing>
        </sites>
        <key_dates>
            <deposition>2020-02-28</deposition>
            <header_release>2020-10-28</header_release>
            <map_release>2020-10-28</map_release>
            <update>2024-10-16</update>
        </key_dates>
        <grant_support>
            <grant_reference>
                <funding_body>German Research Foundation (DFG)</funding_body>
                <code>ZI 552/4-2</code>
                <country>Germany</country>
            </grant_reference>
        </grant_support>
        <title>Cryo-EM structure of a respiratory complex I F89A mutant</title>
        <authors_list>
            <author>Parey K</author>
            <author>Vonck J</author>
        </authors_list>
        <keywords>Complex I, NADH dehydrogenase, Mitochondrion proton pumping, Ubiquinone, Oxidoreductase</keywords>
    </admin>
    <crossreferences>
        <citation_list>
            <primary_citation>
                <journal_citation published="true">
                    <author order="1">Galemou Yoga E</author>
                    <author order="2">Parey K</author>
                    <author order="3">Djurabekova A</author>
                    <author ORCID="0000-0002-1958-8997" order="4">Haapanen O</author>
                    <author order="5">Siegmund K</author>
                    <author ORCID="0000-0003-2155-024X" order="6">Zwicker K</author>
                    <author ORCID="0000-0002-8838-3151" order="7">Sharma V</author>
                    <author ORCID="0000-0001-8461-8817" order="8">Zickermann V</author>
                    <author ORCID="0000-0002-8566-5882" order="9">Angerer H</author>
                    <title>Essential role of accessory subunit LYRM6 in the mechanism of mitochondrial complex I.</title>
                    <journal_abbreviation>Nat Commun</journal_abbreviation>
                    <country>UK</country>
                    <volume>11</volume>
                    <first_page>6008</first_page>
                    <last_page>6008</last_page>
                    <year>2020</year>
                    <external_references type="PUBMED">33243981</external_references>
                    <external_references type="DOI">doi:10.1038/s41467-020-19778-7</external_references>
                    <external_references type="ISSN">2041-1723</external_references>
                </journal_citation>
            </primary_citation>
        </citation_list>
        <pdb_list>
            <pdb_reference>
                <pdb_id>6y79</pdb_id>
                <relationship>
                    <in_frame>FULLOVERLAP</in_frame>
                </relationship>
            </pdb_reference>
        </pdb_list>
    </crossreferences>
    <sample>
        <name>Mitochondrial NADH:ubiquinone oxidoreductase</name>
        <supramolecule_list>
            <complex_supramolecule supramolecule_id="1">
                <name>Mitochondrial NADH:ubiquinone oxidoreductase</name>
                <parent>0</parent>
                <macromolecule_list>
                    <macromolecule>
                        <macromolecule_id>1</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>2</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>3</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>4</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>5</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>6</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>7</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>8</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>9</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>10</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>11</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>12</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>13</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>14</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>15</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>16</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>17</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>18</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>19</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>20</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>21</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>22</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>23</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>24</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>25</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>26</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>27</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>28</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>29</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>30</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>31</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>32</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>33</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>34</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>35</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>36</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>37</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>38</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>39</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>40</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>41</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>42</macromolecule_id>
                    </macromolecule>
                </macromolecule_list>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                    <strain>GB30</strain>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">1</theoretical>
                </molecular_weight>
            </complex_supramolecule>
        </supramolecule_list>
        <macromolecule_list>
            <protein_or_peptide macromolecule_id="1">
                <name>Subunit NUAM of NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.07908807799999999</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MLSRNLSKFARAGLIRPATTSTHTRLFSVSARRLAEIELTIDGHKVSIEAGSALIQACEKAGVTVPRYCYHDKLAIAGNC
RMCLVDVERAPKPVASCAYPVAPGMVVRTDTERVKQARENVMEMMLQNHPLDCPVCDQGGECDLQDQSMRYGRDRGRFTE
ITGKRSTEDKNIGPLVKTSMNRCIHCTRCVRFANDIAGAPELGSSGRGNDMQIGTYLEKNLNTELSGNVIDLCPVGALTN
KPYAFRARPWELKKTESIDVMDAVGSNIRIDSKGVEVMRVIPRVHEDVNEEWINDKSRFACDGLKTQRLTTPLIRVGDKF
VNATWDDALSTIAKAYQQKAPKGDEFKAVAGALVEVESMVALKDMTNALGSENTTTDTPNGNSAPAHGITFRSNYLFNSS
IAGIEDADAILLVGTNPRREAAVMNARIRKAWLRQELEIASVGPTLDATFDVAELGNTHADLEKALSGEFGEVLKNAKNP
LIIVGSGITDREDAGAFFNTIGKFVESTPSVLNENWNGYNVLQRSASRAGAYDIGFTPSDEASKTTPKMVWLLGADEVAA
SDIPADAFVVYQGHNGDVGAQFADVVLPGAAYTEKAGTYVNTEGRSQISRAATGPPGGAREDWKILRAVSEYLGVALPYE
DAYEVRDRLAEISPSLVRYDLVEPTVFGDVAVQHSLVGPNGSVTPSSAPLTETIENFYMTDSISRSSPTMAKSSIAFNKD
NKKNQAFA</string>
                    <external_references type="UNIPROTKB">Q9UUU3</external_references>
                </sequence>
                <ec_number>1.6.99.3</ec_number>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="2">
                <name>Subunit NUBM of NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.053829508</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MLRTTLHKRGLARLSRGFATTQDATPKARQYGGLKDQDRIFQNLYDNYGWDLASARKQGDWYKTKELILKGDTWIIDEIK
KSGLRGRGGAGFPSGLKWSFMNPPGWEKNEGPRYLVVNADEGEPGTCKDREIMRKDPHKLVEGCLLAGRAMNATAAYIYI
RGEFYNEAAVLQTAINEAYAAGLIGKDACGSGYDFDVYIHRGMGAYVCGEETSLIESLEGKAGKPRLKPPFPAGVGLFGR
PSTVTNVETVAVAPTILRRGGDWFASFGRERNSGTKLFCISGNVNEPCTVEEEMSIPLRELLEKHCGGIKGGWDNLLGVI
PGGCSVPILPKNICEDVLMDFDALKDVQSGLGTAAVIVINKQQDVIRAIQRFAAFYKHESCGQCTPCREGTTWLLKAMDR
FRTGQAKEREIDMLYELTKDIEGHTICALGDAAAWPIQGLIRNFRPEMETRMKKFHDEVGAVSVGGWMKDARVEKGKVVG
APLPGVHH</string>
                    <external_references type="UNIPROTKB">Q9UUU2</external_references>
                </sequence>
                <ec_number>7.1.1.2</ec_number>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="3">
                <name>Subunit NUCM of NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.052494906</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MLRSAAARAVRAVRPRLSARYMATTALPQDPIPSGALGQKVPHVDESHQDLLFRTSHMVEDLETYDEDSPINTSDANTRI
RAFTINFGPQHPAAHGVLRLILELSGEEIIRSDPHVGLLHRGTEKLIEYKTYMQALPYFDRLDYVSMMTNEQVFSLAVEK
LLNVEVPLRGKYIRTMFGEITRVLNHLMSVCSHAMDVGALTPFLWGFEEREKLMEFYERVSGARLHAAYVRPGGVSQDLP
AGLLDDIYMWATQFGDRLDEIEELLTDNRIWKLRTVNIGTVTAQDALNLGLSGPMLRGSGIPFDIRKNAPYDAYDKVDFD
VPVGMNGDCYDRYLIRMAEFRQSLRIIEQCCNDMPAGAVKVEDFKINSPPRNLMKEDMEALIHHFLLYTKGYSVPPGETY
TAIEAPKGEMGVYVVSDGSERPYKCKIRAPGFAHLGAFDHIARGHFLPDAVAIIGTMDLVFGEVDR</string>
                    <external_references type="UNIPROTKB">Q9UUU1</external_references>
                </sequence>
                <ec_number>1.6.99.3</ec_number>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="4">
                <name>Subunit NIMM of NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.009806237999999998</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MAIPFEALLPYGIIFGLLTAGGGAMQVLHVYRNGGVRDRFAIDQWDSQMMERDLRLNGGQGRKQVDQATAPEAFKHNHVW
KSERPLI</string>
                    <external_references type="UNIPROTKB">A0A1D8NC63</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="5">
                <name>Subunit NUEM of NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.042765738</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MLRTTRAVKPLKAITTSVRFMNSFENLAQDVNITRSGKTLIAKGTGGRSSRTGYTATVFGANGFLGSYLTAKLAKHGTTV
VVPYREEMAKRHLKVTGDLGVVNFLEMDLRNLESIDEAVRHSDIVVNLIGREYETKNFNYYDVHVEGARRIAEAVKKHNI
ARYIHVSAFNAEIDSPSEFNHTKGLGEQVTKDIVPWATIVRPAPMFGREDKWFLDRMARSPCLVSANKFQETSNPVHVID
VAAALERICFDDSTVAQTFELYGPQKFTQKQIIDMVSETLRKEVRHIELPKALYQAYTKATQAIWWPTYSPDQVERQFLS
QKIDPSAKTFNDLDLTPMELPDLMFKLIRPYRVNTFQHDVSQLENKEKTFVHILD</string>
                    <external_references type="UNIPROTKB">A0A371BY45</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="6">
                <name>Subunit NUFM of NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.016657919999999996</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MRYTQLLRNVSKGVQKSGQSVLVQMREGTPIGLTGIYQHPNPRPALIALYEATLKELQDKHPKDSVYRQSIENLTAHRKQ
IVEDNEVSEVIENKIGAGLIEEVVIQAHEELELAKKMSEWKPWEELEEKPLEDQWVYFNKKGVE</string>
                    <external_references type="UNIPROTKB">A0A371C5F3</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="7">
                <name>Subunit NUGM of NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.032389568</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MLSRFARIGSMGIRPVAAARATFVTSARAAQAAPSWENIKDIRLDPKVHVDEVYEPIVNPADRYLQHVSDLHQYAKYIMA
ALPKYIQGFSVWKDELTLHVAPSAVIPVTTFLRDNTSTQYKSIIDITAVDYPSRENRFEVVYNFLSVRHNSRIRLKTYAT
EVTPVPSITCLYEGANWFEREAYDMYGVFFEGHPDLRRIMTDYGFEGHPLRKDFPLTGYTEVRWDEEKRRVVYEPLELTQ
AFRNFSAGSTAWEPVGPGRDDRPDSFKLPTPKPEEKEGDKK</string>
                    <external_references type="UNIPROTKB">Q9UUU0</external_references>
                </sequence>
                <ec_number>1.6.99.3</ec_number>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="8">
                <name>Subunit NUHM of NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.027247401999999997</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MLRLIRPRLAALARPTTRAPQALNARTHIVSVHRNTENNNPSIPFEFSPENMKRAEEVIAKYPPQYKKAAVMPLLDIGQR
QLGYTSISVMNYVAKLLEMPPMRVYEVATFYTMYNRTPMGRYHLQICTTTPCQLCGSDGIMEAVQNTLNIKPGETTKDNL
FTLSEVECLGACVNAPMMAINDDYYEDLTPEGTVKLLEDCKAGKMPTPGPENHVRRDCEPASGQKVLLSKEPHNVADFLQ
EGI</string>
                    <external_references type="UNIPROTKB">Q9UUT9</external_references>
                </sequence>
                <ec_number>1.6.99.3</ec_number>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="9">
                <name>Subunit NUIM of NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.025682305</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MLSLVRPAVTRSILRGAPGSMRLLSSTARLHAPATDSAINIYAGGSAAAAPPAGFRIHRPATWEESEEGALSKATKYFLL
AEMFRGLYVVLEQFFRAPYTIYYPFEKGPVSPRFRGEHALRRYPSGEERCIACKLCEAICPALAITIDAEERIDGSRRTT
KYDIDMTKCIYCGYCQESCPVDAIVETPNVEYATETREELLYNKEKLLANGDKWELELQYALDADAPYR</string>
                    <external_references type="UNIPROTKB">Q9UUT8</external_references>
                </sequence>
                <ec_number>1.6.99.3</ec_number>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="10">
                <name>Subunit NUJM of NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.020849550999999997</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MSEHVHLPSPTFNTSSAGHFHPYNTLGLATQSAMVGLGAGVVAAAARNSLATGPRNILTTFSKSGGVVTIFTGASIAYVF
TYCSAANLRERKDGWNHMWAGAATGAVLGARTKLVPAFIGWTVLCGAACGLFGWTGARFNADRKASLEQSPKGFVQEDAH
QTFWEVVHRRPLSLTVEQLGEGRGINAVPIATATEAPN</string>
                    <external_references type="UNIPROTKB">A0A371CB65</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="11">
                <name>Subunit NUKM of NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.023455175999999998</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MLRSQIGRLALRPTLVPATVIPQTRAYSAPAGTPRVSSSSMPTDFPLPSQQKPNSAVDYTLTTLDAVANWARQGSFWPVT
FGLACCAVEMMHVSAPRYDQDRLGIIFRASPRQSDIMIVAGTLTNKMAPVLRQVYDQMPEPRWVISMGSCANGGGYYHFS
YSVVRGCDRIVPVDVYVPGCPPTSEALMYGVFQLQRKMRNTKITRMWYRK</string>
                    <external_references type="UNIPROTKB">Q9UUT7</external_references>
                </sequence>
                <ec_number>1.6.99.3</ec_number>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="12">
                <name>Subunit NULM of NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.009815851</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MFIGTIILVLSFLGFVFNRRNIILAFICLETMLLGINLILLRNSVLFDDISGSLFAIVIIILAGVESAIGLSLLVSYYRL
RGVINSYGI</string>
                    <external_references type="UNIPROTKB">Q9B6D4</external_references>
                </sequence>
                <ec_number>7.1.1.2</ec_number>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="13">
                <name>Subunit NUMM of protein NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.01514897</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MLSRFVSKRAFSVSTQVSKSIISYNGNTIEIPEEYTKQAPNRDSTWAPAQASKTEIYKNNMVRFEQKDLSKQPMPYAGIE
LIAQQPVRFVHGNTAVCDGANHNGPGAQGHPKIFINVDAPGSHACQYCGTRYEKEH</string>
                    <external_references type="UNIPROTKB">A0A1H6Q8Z5</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="14">
                <name>Acyl carrier protein ACPM1 of NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.012053584999999999</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MLRNVSRLALRSNFARQATMGQRFYSVARPDAEKRIAAVLESFDKISNPAAITPTASFAKDLNLDSLDTVEVVVAIEEEF
GIEIPDKEADEIKSVNQAVEYILAQPDAK</string>
                    <external_references type="UNIPROTKB">A0A1H6PXT9</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="15">
                <name>Subunit NB4M of protein NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.014702720999999998</theoretical>
                </molecular_weight>
                <details>Subunit NB4M of protein NADH:Ubiquinone Oxidoreductase (Complex I)</details>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MAIIATAFAETVKFSGSKQELQKRTLALYRQFLRGAPTFADLYEVQFSIPTIRTKIRQEFERHRFVDDLSIQNVLYAKGH
MEYQECINAWKQQAQFLKYFPEEDDIQGRHQPSNFVDKFLKNRA</string>
                    <external_references type="UNIPROTKB">A0A1D8N3C8</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="16">
                <name>Acyl carrier protein ACPM2 of NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.014444458</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MLRQSVLRLSRAAVARPALSRSFVTAVARPQLVRAAPVSFIRHYSSAHVLTKDMIQERIVALLESFDKVNDAKNITATAN
LTSDLGLDSLDVVEVVMAIEEEFGLEIPDHDADEIKTVQQAIDYVSAQPAAV</string>
                    <external_references type="UNIPROTKB">A0A1D8NG21</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="17">
                <name>Subunit NI2M of NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.01290287</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MSHPVPFSAANKKLVTSMYRQSLKLARNWISNRQLFRQKAVEIRHKFDQNAQISNPRLLARTLDETRAHLYEFRHPDPIV
PPSFPGGTKYERNVPPRMEKIMQHNLYEP</string>
                    <external_references type="UNIPROTKB">A0A1D8NDL1</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="18">
                <name>Subunit NESM of NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.028479940999999998</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MLKLHYRNFITAQHSTTNTTPTMIASVCKRAGLRAGPRAYPGVRQFALRAYNEEKELALKQRLSQLPPPGKAFVTAEGEP
RPAKEAELAELAEIAALYKTDRVGILDILLLGNKHARLYRDNTALLKDYYYNGRRILDKIPVKDKQTGKVTWEIKREGAE
KEDWVNQMYFLYAPSLILLLIVMVYKSREDITFWAKKELDQRVLDKHPEINDAPENERDALIVERIIAGDYDKLASLQKK
ATPTPATLI</string>
                    <external_references type="UNIPROTKB">Q6ZY23</external_references>
                </sequence>
                <ec_number>1.6.99.3</ec_number>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="19">
                <name>Subunit NUPM of NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.019355196999999998</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MPREAAAHWVPFEDKANMPDNVPDVVEVGATSAPLLSASYFIGAKCKPYNDDFMLCREESQGSGAIDCLKEGRRVTRCAV
SVIEDINKSCLDEFRLHWQCLEQNNHQLSGCRKAEALLNKCVFTKLNLEKKIPGLRPDEEPVFLKKDPWIKPAVDDFKSV
RAYAEAKKNGTL</string>
                    <external_references type="UNIPROTKB">A0A371C2D0</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="20">
                <name>Subunit NB6M of NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.014112429</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MPSVGQDLPPVGGYEPVQWRRNLPARGFRPLVYLAALCGICGYGFYRALGGIQERRELKREKLWARIYLMPLLQAEEDRQ
TVRRSIAQLEREKEIMKGTGFDVDKSVYNDGKFHAPALMIPPK</string>
                    <external_references type="UNIPROTKB">A0A1H6PPE5</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="21">
                <name>Subunit NUXM of NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.018588208999999998</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MSSSTPLVKTSVNYSYGDYPLIDADPHFKRVVGYMRPSDYGVIGLATAALPAGICFAEWLDPVKGKFARPSVKFLRVATM
LGFAVGFGAAYARSSLRFFGVTENAREYKKDEAQMAARKAAGLEPYGTSSLTPELQEIAAKNSAHSIAGLFIFPWFNFVN
HPYHGREQK</string>
                    <external_references type="UNIPROTKB">A0A1D8NKB4</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="22">
                <name>Subunit NUYM of NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.018656080000000002</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MLSRSLRQLSQPSVRSFATSARLLQKKDVPEVGVNLDNVPAHEIVSGAPAELSRNRVVRIYQQAKPATQSGEYGTFAWRL
DWDIVDVANRWENDLIGWQSSGDYMQATQMKFTSKESAIKFANKQGWDFYIQEPHHRKFRVKQYANNFVHSYGKLKHIRT
K</string>
                    <external_references type="UNIPROTKB">A0A1D8N7X0</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="23">
                <name>Subunit NUZM of NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.019772525</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MLPGGPVPVFKKYTVGSKGIWEKLRVLLAIAPNRSTGNPIVPLYRVPTPGSRPEANVYQDPSSYPTNDIAENPYWKRDHR
RAYPQTAFFDQKTVTGLLELGSEATPRIADGEAGTKALANIANGGVSFTQALGKSSKDVIYGEVLTVNGLPPVAPTLAPK
QWKIIEGEAAIYPKGYPCRTFH</string>
                    <external_references type="UNIPROTKB">A0A1D8N3H5</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="24">
                <name>Subunit NIAM of NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.017328523000000002</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MLSRRAVTMLRSPVARVAQVQVRGIRASFDKAEEPMLGDYPDIDPFPAQLKNPYKKYDDQQDRRNLEEPLSVNDDLYDMW
SPDRFTHFKNQDALKYFIGFLTIFFGASYVATYFVPEKAAIPREFPYEGLWKESGGTEKSKAFFGQRSE</string>
                    <external_references type="UNIPROTKB">A0A1D8ND94</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="25">
                <name>Subunit NEBM of NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.008059366</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MALFTSLVGASGLGFATKFLSNKIRLKPAGYYPLGYVFSGVAWAGLGLVLHNVHQHSLEVLEKKKTALSEQRTE</string>
                    <external_references type="UNIPROTKB">A0A1D8NGI5</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="26">
                <name>Subunit NB2M of NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.006948902</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MAPQLKDPWARREAWRYQTNFTRANRFKGAAPGFGIAVVAFGAYLAAEKFLFEKKDDHHH</string>
                    <external_references type="UNIPROTKB">A0A371C0F2</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="27">
                <name>Subunit NIDM of NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.011039275999999999</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MSEHQRPELVSFDDINYNDHKKVREAQESYTREQFIRLEALKTVRKALEKCYEESGPNHFEDCKNLAEQYLDMLPTHRLQ
GYLGYQRNDPSK</string>
                    <external_references type="UNIPROTKB">A0A1D8N596</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="28">
                <name>Subunit NUVM of NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.007807067</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MAGHHTNYKWNGPLPRPHVSAGHRIATKFLGATMFFWMFLRIKEEYPAMLGLHNFYPPKEGEKAVEH</string>
                    <external_references type="UNIPROTKB">A0A1D8NFX6</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="29">
                <name>Subunit NI8M of NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.009621050999999999</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MSAALREIRFHLCQNGSSSAPLRQFVKNQIGAFQKANPSTKVLVREANGVKPIVFARFDHGHESKIGLDVSSEKEVAERV
KSLIEAK</string>
                    <external_references type="UNIPROTKB">A0A1H6PJS3</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="30">
                <name>Subunit NI9M of NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.008921152</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MINANPGFWNGPFRYLRWSAHNRPHLFFAFAIGIAGPVAALTLTPLRRKYLYPDHSPLPQSYPLPQRAREGLTGFDDE</string>
                    <external_references type="UNIPROTKB">A0A1D8NJR0</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="31">
                <name>Subunit N7BM of NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.016175141</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MSSSLYRVLRNAWEVGPRSYWKQLNSIGDTKSGRLVGTDIYGNKFYETDHQDEIHLRTRYVEYKEKDYDMSQVEPGWHFW
LGYGVDTAPCNTPKEKLPIRAYPYKFQPNYTGTPGAFVTYNTLKPKISAWEPVTKQRS</string>
                    <external_references type="UNIPROTKB">A0A1D8N5V2</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="32">
                <name>Subunit NUUM of NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.009793966</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MGGGRYPFPKDVISMTGGWWANPSNWKLNGLFATGIAVGLALWVSTATLPYTRRREGITSESDISKWNAAAGVWRERHGK
ISTGEAAESE</string>
                    <external_references type="UNIPROTKB">A0A1H6Q311</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="33">
                <name>Subunit NB5M of NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.010494884999999999</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MVELKPSSAIQRGPLNKGGWDAPHALHNDGAIDRYAHWRTFYQERFKYTRATGKSTLIFLVAFPALIGYVAYQSEGLFEF
AGKRRGESVTTRG</string>
                    <external_references type="UNIPROTKB">Q6ZY24</external_references>
                </sequence>
                <ec_number>1.6.99.3</ec_number>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="34">
                <name>Subunit NUNM of NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.013523068</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>FGSHGHGPELTPAVPFFQPYVLKWAGVSLGLVAFYQFNSSYEAKNGHTWVETFFHPKSREDILNEEAKIVQALNNQRELT
IKMHELKREEKDYAHSYSPLFSDPVPQGGSIGKAPGSSRE</string>
                    <external_references type="UNIPROTKB">A0A371CFV9</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="35">
                <name>Subunit NU1M of NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.038361266000000005</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MIINIVEILIFLVCVLFSVAYLTVAERKTLAYMQRRLGPNFVGYYGLLQAFADAVKLLLKEIVLPKESNYIILVISPLIT
LITALIGWVVIPLGPGITLGELNLGILFSLAIGSLGVFGSLLSGWSSNSKYSLLGSIRSTAQLISYELILTSIFIIIIMF
VSSLNITTIIETQRVVWYCIPLLPLLLIFFIASVAETARPPFDLTESESELVAGYFTEYSGSPFVFFFLAEYSNIILISA
FNGYLLLGGYLSFNYSYLFNILFNDYSYVSFLFEGLINSSAYAIKLVFLMFSFIWVRAAFPRFTYDNLINFCWIILLPLL
FGIFLIIPSTLYIFDSFPTLI</string>
                    <external_references type="UNIPROTKB">S5U3V2</external_references>
                </sequence>
                <ec_number>7.1.1.2</ec_number>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="36">
                <name>Subunit NU2M of NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.053353358999999996</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MLILAIISLITFVSMSKLSDNRAIIRLINIYLILVLVLDSFLYLLFLNNQTYTVMGELLIFNSFTFYIDMLIYFIMIVIS
SLYGYNLYNNNLYKTLFEPKKELIILFLINILGALLIVHSNDFITLFVAIELQSYSIYLITAIYNSSYKASKASMLYFFM
GGILSILIAYSINTYYSVLNSYTLHSLDSLIINTLDLNLILIALSLGLLFKIGIAPLHKWLISIYENTPILITIYISLIP
KISILSYLVLSNISINSLVISILAILTLLVGSVGGLLQIKIKRLLAFSGLTNAGYMMLLLLLNNNEFSYLYYITQYSISH
LAIFMIIIFSIYYINYINNQYNPIIYVNQLKGLIHDNAYLVLSMAIVVFSFIGIPPLLGFFGKLNILMSILNNGYYFISI
VLIVASLISALYYLYLLNVSIQDKNNILINSNETVSSVLSYILSSLIILITFGFIYNSLIIDIFNVYFN</string>
                    <external_references type="UNIPROTKB">S5U4R9</external_references>
                </sequence>
                <ec_number>1.6.5.3</ec_number>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="37">
                <name>Subunit NU3M of NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.014478329</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MNTFIIFIILIPIVGFALLAVNILLAVYKPYNEKLGAFECGLTSFNQTRLAFNAAFILVAILFLPFDLEISTLLPYVMSI
YLVSNYGFTIVLLFLLILIIGFVYEINTNALKINKHNKPNTDSLIYKL</string>
                    <external_references type="UNIPROTKB">S5TMS4</external_references>
                </sequence>
                <ec_number>7.1.1.2</ec_number>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="38">
                <name>Subunit NU4M of NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.054506641</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MFLTSILLSSLYLFNRILAWQGNVKHFYLFASNLLLLFIVVLYINFNTFSNSFQFNFELFNSLNPFGLSNSDISNGLLFG
IDGLSLTFILLTVLLIPLTLLGNWYNINFNSNLYYTLVLAIGLVILLNFWALDYISFYILFEATLPLLFILIHIYGSSDS
ERASFYVLMFTLSGSLFMLLSIVVISIVLNTTNFINHNLFVLSLDLQTIIWLGLFIAIMVKTPLFPIHVWLPVVHSESPL
AGSMILAGLILKLALYAILRLLLPLLCEAQILYTPMIYIISLLTIILTSLATLRQIDLKVIIAYSSISHMGIAILGVCSN
TSLGIYGSIVLGVAHGFVSPALFLIVGGILYDRYHIRIVNYYKGLTTYMPQLATYIIILSFANIGTPLTGNFTGEFLSLQ
GGFIRNPIIGGISCISVLLAAIYQLKLTNKLTGGISSIYMHRTNDVTIREKFIMNILIISTLIIGICPQIMYNLLYWTVN
NYIYII</string>
                    <external_references type="UNIPROTKB">S5TMP9</external_references>
                </sequence>
                <ec_number>7.1.1.2</ec_number>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="39">
                <name>Subunit NU5M of NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.07374068799999998</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MYNAISLIIILPCISWLFPLFFGRQLGYVFVTRMTSTLIIITTLITYYYFYQLLGNNNPINLELFNYLNIDYLDINYNFE
IDALTITMLLAITTISSMVHIYSIGYMETDPHQVRFFSLLSMFTFWMIILVTGSNYFVLFVGWEFIGVTSYLLISFWVTR
LQAMKSALSAVLMNRFGDAFFVLGLCVIAYVFGTLNYSTIFATAYLINTDLLVLIMLALFIAAMAKSAQFGLHNWLTLAM
EGPTPVSSLLHAATLVTAGIYLLLRSANILEYTPTVLFIILWIGALTTLSAGLIAICSNDLKRIIALSTMSQLGMMTIAI
GLSAYNLALFHLLGHAFFKALLFMSAGSIIHSILNESQDIRTYGGLLSYLPYTYICITIASLSLMAMPGLTGYYTKDIII
ESTYGSYSISNYVVYWIAYLSAVLTCVYSMKILYLTFYSNPNNNTITYYNAHESNIYITLPMFILAIFAMFAGWILKDIY
LGVGTDFVGTHILPNNFSYFDTEFSITQFYKLLPLISAILVSILIVVLNEFFAIVFNLNNKYINTVYSIFNQKLVSDQIL
NHFIIFKGLVTSGNIAHHVDKGSLYRLGPVGINRLLNKASYNVINLSSNTRSSLSMNSMLILITIVSLLLLVLVMNVNFI
IVIPVLISILYILFS</string>
                    <external_references type="UNIPROTKB">S5TF58</external_references>
                </sequence>
                <ec_number>7.1.1.2</ec_number>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="40">
                <name>Subunit NU6M of NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.020765101999999997</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MMYLTYYFIEITIFLAILCTIFIISAKNPMVSILYMIALFVIAAMYLYLIGLGIFSLLYIMIYIGAIAVLFLFIITLLDI
NSTELSVKSNIRDLPLVLISLIVLTISGLMIYSNDSILINKLLEAFGNDYNTIITQDWFNIENTTLLTTIGNVLLTNNAF
ILLVLAIVLLLGIIGPISITMKHKE</string>
                    <external_references type="UNIPROTKB">Q9B6E9</external_references>
                </sequence>
                <ec_number>7.1.1.2</ec_number>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="41">
                <name>Subunit NB8M of NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.011219027</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MAEFPPLLSQEDMKKHKILLAYRDRCAALLVPLNECRKKNYYMPWACGHERHEYEMCEVADFQRRVKAMDKLKAEKIEQA
KAAAAAAAAAAAADAEESK</string>
                    <external_references type="UNIPROTKB">A0A1H6PKH9</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="42">
                <name>Subunit NIPM of NADH:Ubiquinone Oxidoreductase (Complex I)</name>
                <natural_source database="NCBI">
                    <organism ncbi="4952">Yarrowia lipolytica</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.010035651</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MTAAGISLTGGRNRCFSEWQSFMHCTAKTDAKSRAQCLPNFEDYMECLHHTKEKARLREIESVLKQKKEGLEAPPVKVIP
VKAIGLVEE</string>
                    <external_references type="UNIPROTKB">A0A1D8NNZ0</external_references>
                </sequence>
            </protein_or_peptide>
            <ligand macromolecule_id="43">
                <name>IRON/SULFUR CLUSTER</name>
                <molecular_weight>
                    <theoretical units="MDa">0.00035163999999999996</theoretical>
                </molecular_weight>
                <number_of_copies>6</number_of_copies>
                <formula>SF4</formula>
            </ligand>
            <ligand macromolecule_id="44">
                <name>FE2/S2 (INORGANIC) CLUSTER</name>
                <molecular_weight>
                    <theoretical units="MDa">0.00017581999999999998</theoretical>
                </molecular_weight>
                <number_of_copies>2</number_of_copies>
                <formula>FES</formula>
            </ligand>
            <ligand macromolecule_id="45">
                <name>FLAVIN MONONUCLEOTIDE</name>
                <molecular_weight>
                    <theoretical units="MDa">0.00045634399999999997</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <formula>FMN</formula>
            </ligand>
            <ligand macromolecule_id="46">
                <name>NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE</name>
                <molecular_weight>
                    <theoretical units="MDa">0.000745421</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <formula>NDP</formula>
            </ligand>
            <ligand macromolecule_id="47">
                <name>1,2-Distearoyl-sn-glycerophosphoethanolamine</name>
                <molecular_weight>
                    <theoretical units="MDa">0.000748065</theoretical>
                </molecular_weight>
                <number_of_copies>11</number_of_copies>
                <formula>3PE</formula>
            </ligand>
            <ligand macromolecule_id="48">
                <name>Lauryl Maltose Neopentyl Glycol</name>
                <molecular_weight>
                    <theoretical units="MDa">0.001005188</theoretical>
                </molecular_weight>
                <number_of_copies>3</number_of_copies>
                <formula>LMN</formula>
            </ligand>
            <ligand macromolecule_id="49">
                <name>ZINC ION</name>
                <molecular_weight>
                    <theoretical units="MDa">6.5409e-05</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <formula>ZN</formula>
            </ligand>
            <ligand macromolecule_id="50">
                <name>S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate</name>
                <molecular_weight>
                    <theoretical units="MDa">0.000568704</theoretical>
                </molecular_weight>
                <number_of_copies>2</number_of_copies>
                <formula>ZMP</formula>
            </ligand>
            <ligand macromolecule_id="51">
                <name>DIUNDECYL PHOSPHATIDYL CHOLINE</name>
                <molecular_weight>
                    <theoretical units="MDa">0.000622834</theoretical>
                </molecular_weight>
                <number_of_copies>6</number_of_copies>
                <formula>PLC</formula>
            </ligand>
            <ligand macromolecule_id="52">
                <name>CARDIOLIPIN</name>
                <molecular_weight>
                    <theoretical units="MDa">0.0014640429999999997</theoretical>
                </molecular_weight>
                <number_of_copies>5</number_of_copies>
                <formula>CDL</formula>
            </ligand>
            <ligand macromolecule_id="53">
                <name>Ubiquinone-9</name>
                <molecular_weight>
                    <theoretical units="MDa">0.000795226</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <formula>UQ9</formula>
            </ligand>
            <ligand macromolecule_id="54">
                <name>Phosphatidylinositol</name>
                <molecular_weight>
                    <theoretical units="MDa">0.000887128</theoretical>
                </molecular_weight>
                <number_of_copies>4</number_of_copies>
                <formula>T7X</formula>
            </ligand>
            <ligand macromolecule_id="55">
                <name>(7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE</name>
                <molecular_weight>
                    <theoretical units="MDa">0.0007590679999999999</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <formula>PSC</formula>
            </ligand>
        </macromolecule_list>
    </sample>
    <structure_determination_list>
        <structure_determination structure_determination_id="1">
            <method>singleParticle</method>
            <aggregation_state>particle</aggregation_state>
            <specimen_preparation_list>
                <single_particle_preparation preparation_id="1">
                    <concentration units="mg/mL">1.5</concentration>
                    <buffer>
                        <ph>7.2</ph>
                        <component>
                            <concentration units="mM">20.0</concentration>
                            <formula>Tris</formula>
                        </component>
                        <component>
                            <concentration units="mM">100.0</concentration>
                            <formula>NaCl</formula>
                            <name>sodium cloride</name>
                        </component>
                        <component>
                            <concentration units="mM">1.0</concentration>
                            <formula>EDTA</formula>
                        </component>
                        <component>
                            <concentration units="%">0.025</concentration>
                            <formula>LMNG</formula>
                        </component>
                    </buffer>
                    <grid>
                        <model>C-flat-1.2/1.3</model>
                        <material>COPPER</material>
                        <pretreatment>
                            <type>GLOW DISCHARGE</type>
                            <atmosphere>AIR</atmosphere>
                        </pretreatment>
                    </grid>
                    <vitrification>
                        <cryogen_name>ETHANE</cryogen_name>
                        <chamber_humidity units="percentage">80</chamber_humidity>
                        <chamber_temperature units="K">283</chamber_temperature>
                        <instrument>FEI VITROBOT MARK IV</instrument>
                    </vitrification>
                </single_particle_preparation>
            </specimen_preparation_list>
            <microscopy_list>
                <single_particle_microscopy microscopy_id="1">
                    <microscope>FEI TITAN KRIOS</microscope>
                    <illumination_mode>FLOOD BEAM</illumination_mode>
                    <imaging_mode>BRIGHT FIELD</imaging_mode>
                    <electron_source>FIELD EMISSION GUN</electron_source>
                    <acceleration_voltage units="kV">300</acceleration_voltage>
                    <nominal_cs units="mm">2.7</nominal_cs>
                    <nominal_defocus_min units="µm">-1.5</nominal_defocus_min>
                    <nominal_defocus_max units="µm">-2.5</nominal_defocus_max>
                    <nominal_magnification>105000.0</nominal_magnification>
                    <specimen_holder_model>FEI TITAN KRIOS AUTOGRID HOLDER</specimen_holder_model>
                    <cooling_holder_cryogen>NITROGEN</cooling_holder_cryogen>
                    <alignment_procedure>
                        <coma_free/>
                    </alignment_procedure>
                    <specialist_optics>
                        <energy_filter>
                            <name>GIF Bioquantum</name>
                            <slit_width units="eV">30</slit_width>
                        </energy_filter>
                    </specialist_optics>
                    <image_recording_list>
                        <image_recording image_recording_id="1">
                            <film_or_detector_model>GATAN K3 (6k x 4k)</film_or_detector_model>
                            <detector_mode>COUNTING</detector_mode>
                            <digitization_details/>
                            <number_real_images>2016</number_real_images>
                            <average_exposure_time units="s">3.0</average_exposure_time>
                            <average_electron_dose_per_image units="e/Å^2">51.8</average_electron_dose_per_image>
                        </image_recording>
                    </image_recording_list>
                </single_particle_microscopy>
            </microscopy_list>
            <singleparticle_processing image_processing_id="1">
                <image_recording_id>1</image_recording_id>
                <particle_selection>
                    <number_selected>479372</number_selected>
                </particle_selection>
                <startup_model type_of_model="EMDB MAP">
                    <emdb_id>EMD-4873</emdb_id>
                </startup_model>
                <final_reconstruction>
                    <number_classes_used>1</number_classes_used>
                    <applied_symmetry>
                        <point_group>C1</point_group>
                    </applied_symmetry>
                    <resolution units="Å" res_type="BY AUTHOR">2.96</resolution>
                    <resolution_method>FSC 0.143 CUT-OFF</resolution_method>
                    <software_list>
                        <software>
                            <name>RELION</name>
                            <version>3.0</version>
                        </software>
                    </software_list>
                    <number_images_used>143203</number_images_used>
                </final_reconstruction>
                <initial_angle_assignment>
                    <type>MAXIMUM LIKELIHOOD</type>
                    <software_list>
                        <software>
                            <name>RELION</name>
                            <version>3.0</version>
                        </software>
                    </software_list>
                </initial_angle_assignment>
                <final_angle_assignment>
                    <type>MAXIMUM LIKELIHOOD</type>
                    <software_list>
                        <software>
                            <name>RELION</name>
                            <version>3.0</version>
                        </software>
                    </software_list>
                </final_angle_assignment>
                <final_three_d_classification>
                    <number_classes>3</number_classes>
                    <software_list>
                        <software>
                            <name>RELION</name>
                            <version>3.0</version>
                        </software>
                    </software_list>
                </final_three_d_classification>
            </singleparticle_processing>
        </structure_determination>
    </structure_determination_list>
    <map format="CCP4" size_kbytes="256001">
        <file>emd_10711.map.gz</file>
        <symmetry>
            <space_group>1</space_group>
        </symmetry>
        <data_type>IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES)</data_type>
        <dimensions>
            <col>400</col>
            <row>400</row>
            <sec>400</sec>
        </dimensions>
        <origin>
            <col>0</col>
            <row>0</row>
            <sec>0</sec>
        </origin>
        <spacing>
            <x>400</x>
            <y>400</y>
            <z>400</z>
        </spacing>
        <cell>
            <a units="Å">334.80002</a>
            <b units="Å">334.80002</b>
            <c units="Å">334.80002</c>
            <alpha units="deg">90.0</alpha>
            <beta units="deg">90.0</beta>
            <gamma units="deg">90.0</gamma>
        </cell>
        <axis_order>
            <fast>X</fast>
            <medium>Y</medium>
            <slow>Z</slow>
        </axis_order>
        <statistics>
            <minimum>-0.06999521</minimum>
            <maximum>0.13368793</maximum>
            <average>-0.00000040657437</average>
            <std>0.0039716214</std>
        </statistics>
        <pixel_spacing>
            <x units="Å">0.8370001</x>
            <y units="Å">0.8370001</y>
            <z units="Å">0.8370001</z>
        </pixel_spacing>
        <contour_list>
            <contour primary="true">
                <level>0.013</level>
                <source>AUTHOR</source>
            </contour>
        </contour_list>
        <label>::::EMDATABANK.org::::EMD-10711::::</label>
    </map>
    <interpretation>
        <modelling_list>
            <modelling>
                <initial_model>
                    <access_code>6RFR</access_code>
                    <chain>
                        <source_name>PDB</source_name>
                        <initial_model_type>experimental model</initial_model_type>
                    </chain>
                </initial_model>
                <refinement_protocol>OTHER</refinement_protocol>
                <refinement_space>REAL</refinement_space>
                <overall_bvalue>30.0</overall_bvalue>
            </modelling>
        </modelling_list>
    </interpretation>
</emd>
