2025-10-01 REL PDBe INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY STRUCTURE_SUMMARY database_2 em_admin _chem_comp.pdbx_synonyms _database_2.pdbx_DOI _database_2.pdbx_database_accession _em_admin.last_update REMEDIATION REPOSITORY Carbohydrate remediation STRUCTURE_SUMMARY atom_site chem_comp database_PDB_caveat entity pdbx_branch_scheme pdbx_chem_comp_identifier pdbx_entity_branch pdbx_entity_branch_descriptor pdbx_entity_branch_link pdbx_entity_branch_list pdbx_entity_nonpoly pdbx_nonpoly_scheme pdbx_struct_assembly_gen pdbx_validate_chiral struct_asym struct_conn struct_site struct_site_gen _atom_site.B_iso_or_equiv _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.auth_comp_id _atom_site.auth_seq_id _atom_site.label_asym_id _atom_site.label_atom_id _atom_site.label_comp_id _atom_site.label_entity_id _atom_site.type_symbol _chem_comp.name _database_PDB_caveat.text _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_struct_assembly_gen.asym_id_list _pdbx_validate_chiral.auth_asym_id _pdbx_validate_chiral.auth_seq_id _struct_conn.pdbx_role _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_label_asym_id STRUCTURE_SUMMARY chem_comp chem_comp_atom chem_comp_bond database_2 em_admin pdbx_entry_details pdbx_modification_feature _chem_comp.pdbx_synonyms _database_2.pdbx_DOI _database_2.pdbx_database_accession _em_admin.last_update _pdbx_entry_details.has_protein_modification STRUCTURE_SUMMARY em_admin pdbx_modification_feature pdbx_validate_close_contact struct_conn _em_admin.last_update EXPERIMENTAL_SUMMARY em_admin _em_admin.last_update PDBe PDBe 2019-11-04 2020-06-03 2020-06-03 2025-10-01 Swiss National Science Foundation 150665 & 176992 Switzerland Structure of Drosophila melanogaster Dispatched Korkhov VM Cannac F RND transporter, transmembrane domain, ectodomain, cholesteryl hemisuccinate, detergent micelle, digitonin, monomer, MEMBRANE PROTEIN Cannac F Qi C Falschlunger J Hausmann G Basler K Korkhov VM Cryo-EM structure of the Hedgehog release protein Dispatched. Sci Adv US 6 eaay7928 eaay7928 2020 32494603 doi:10.1126/sciadv.aay7928 2375-2548 6tbu FULLOVERLAP EMDB EMD-10452 associated EM volume
Structure of Drosophila melanogaster Dispatched
 Drosophila melanogaster protein Dispatched (disp) Drosophila melanogaster protein Dispatched (disp) 0 1 Drosophila melanogaster 0.139 Protein dispatched Drosophila melanogaster 0.139149875
Drosophila melanogaster Dispatched, tagged with a C-terminal 3C-protease cleavage site, YFP and twin-strep tag.
1 Homo sapiens LEVO MLCFDSERMNWYYHVLARRPYLVVVSIAVYCVACIIVALVLNKLPDFSDPTLGFETRGTKIGERLTAWYNLLQETDHHGA LFSNPSDLWERRRVEQGYVETKLHPNHRRRKNKHKNRNKNKRRKEQNQSSHEHHDVAQKMMQFKKRLKATSSPSPNLGFD TWIGDSGVFRDYEITNDSASSSLEPTRRTEQIEYGHNTTSVDEEEHQQRVQTKKSTWRLLKQAATLPTDGWADMHRRQPI EGFFCDSSPRKEYSHFVVQRIGPNATDSLFDLNGLLAMCQLQDQITEVPSYRAFCEPEMLTTECCRPWSLPNYAAMLANK SSCFDLTTEDVTSLHTLLLGCYEYFHDLKMDNHCNEIPHCRAPEECKRLNIVFNVLNFLTDFSFIKSNDSNVYLKYAMIF IPVAQSNRLLPLFHEWEDVELINELVEVVAMDLGLENELFNELLLTDVWLVSLGGTFVMASVWLYTGSAFITLMSCVAIC FSLGLAYFFYAIVLEFEFFPYMNLLAVVVIIGIGADDVFLFLKIWHCVLTERFSNRCTLTTQSQSALPTLENSDHTESLE NIMALTMRHAAASMFVTSLTTAGAFYASYSSSITAIKCFGIFAGTVVVTNYLLMITWLPASVSIMERLFATRMSCHHPMS IKLIHACKKSINRFCQMFEECITKSIMNYAYLWLLIFGALGASSAVIVFWYPGLQLPEKSHFQLFVSKHPFEVYSSLKQQ FWFEKPLQAYYNFKMHMHFVWGVQAVDDGDYTNPNSYGHLHYDNNFNVSSRPAQLWILDFCQSVRQQPFYKETLGMLLPN CFIENLIDYMKRRCIDDMDSTRKDRSPCCDAQFPFEPHIFEYCLPQSISNMYDTTFFRPGVAGPKFAEAPRLETEDYLGM SGNESAEYSTNGSFTPLLVKALVIEFESNVAYSTIYANIRQFYESVEHWFQMQLKTAPPELQGGWFTSDLKFYNVQDTLS HDTFVAICLAMAASLAVLLCFTVNILISIYAVLTVSLSIFNTVAVLILLGWQLNILESIAVSTAIGLAVDFSLHYGIHYR MSPVKERLAATQFVLSRIIGPTVMAATTTGLAGGIMMASNILPYIQIGVFLVVVMIVSWFYATFFLMSLLRVAGPQHGFL ELKWPLWSKRSSGSSKFYERKPSQVIASEQLLTPTSSAIVELANSETHELESLNSNSLIKTISGIESAHALSSLPRDFEH SFQTMHECKYQTYPSTSN Q9VNJ5 CHOLESTEROL HEMISUCCINATE 0.000486726 9 Y01 2-acetamido-2-deoxy-beta-D-glucopyranose 0.000221208 1 NAG singleParticle particle 8.0 ETHANE FEI TITAN KRIOS FLOOD BEAM BRIGHT FIELD FIELD EMISSION GUN 300 0.8 2.4 GATAN K2 QUANTUM (4k x 4k) COUNTING 9216 50.0 1 PHASE FLIPPING AND AMPLITUDE CORRECTION
The initial model was generated using preliminary data collected with Jeol JEM2200 microscope.
 C1 3.16 FSC 0.143 CUT-OFF RELION 3.0 286136 MAXIMUM LIKELIHOOD MAXIMUM LIKELIHOOD RELION 3.0 RELION 3.0 emd_10452.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 304 304 304 0 0 0 304 304 304 246.24 246.24 246.24 90.0 90.0 90.0 X Y Z -0.04071731 0.07844124 0.00008505661 0.001553409 0.81 0.81 0.81 0.015 AUTHOR Drosophila melanogaster Dispatched