2024-09-25 REL PDBe PDBe PDBe 2019-11-01 2020-02-12 2020-02-12 2024-09-25 French National Research Agency ANR-15-CE11-0022-01 France French National Research Agency ANR-10-LABX-0030-INRT France French National Research Agency ANR-10-IDEX-0002-02 France Papai G Frechard A Transcriptional co-activator, Histone-acetylation, TRANSCRIPTION Papai G Frechard A Kolesnikova O Crucifix C Schultz P Ben-Shem A Nature UK 577 711 716 2020 31969704 doi:10.1038/s41586-020-1944-2 1476-4687 0006 NATUAS EMD-10438 other EM volume EMD-10440 other EM volume EMD-10441 other EM volume 6tbm FULLOVERLAP SAGA bound to TBP SAGA bound to TBP 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 1.6 TATA-box binding protein (TBP) 1 1 Komagataella phaffii GS115 SAGA component 1 3 Komagataella phaffii GS115 Polyubiquitin-B 1 15 Homo sapiens SAGA complex 1 2 4 5 6 7 8 9 10 11 12 13 14 16 17 18 Komagataella phaffii GS115 TATA-box Binding Protein (TBP) Komagataella phaffii (strain GS115 / ATCC 20864) 0.027042275 1 Escherichia coli LEVO MADEERLKEFKEANKIVFDPNTRQVWENQNRDGTKPATTFQSEEDIKRAAPESEKDTSATSGIVPTLQNIVATVTLGCRL DLKTVALHARNAEYNPKRFAAVIMRIREPKTTALIFASGKMVVTGAKSEDDSKLASRKYARIIQKIGFAAKFTDFKIQNI VGSCDVKFPIRLEGLAFSHGTFSSYEPELFPGLIYRMVKPKIVLLIFVSGKIVLTGAKQREEIYQAFEAIYPVLSEFRKM Transcriptional coactivator HFI1/ADA1 Komagataella phaffii (strain GS115 / ATCC 20864) GS115 / ATCC 20864 0.049888273 1 LEVO MASTELVASTPMPSRNGQGSHQKLNGGNVNSATNTPTVASTPVNQPRKLPSENFSGLGGAIRIEIEPLVVDFQRRLGKNW GRYQIAVSLFLVGKLSRRELVDELDDILDRNTVKMHNQLLLGNLANSLKESAGDRVGSGGFGGSMFNKRVKDSRKSSQYE RLKRDILALPVRERRRIKAITRESGKKGMVNSVITQTRQALIPKVPVVTRPTNVPGNSVQWAQDVIHGFQALLASEIYEL PEMDNLRTRMTGISREHGLIGPVDDSVIEIMLIGLEQHLKGIVEAAIDIVKYRRTKYTNNSVVDTLQKEQTNTSDTSSSK VSRKRDRHTLTIEDMYDTLEQYPYLVEPGGTLLRLQSVMLHDEDELSDDEILKHILKPRTSDSTDRKPKQLQENGTADSL SKVTKSITNGANASGDAVPNGKAEHIQNTMGTKEELNWFIYDILSNNE C4QZA3 Subunit of SAGA histone acetyltransferase complex Komagataella phaffii (strain GS115 / ATCC 20864) GS115 / ATCC 20864 0.079995227 1 Escherichia coli LEVO MQNPERPVVWKELGQYLDTLQPIHQEKPSSLPDLPSPSYKDSLSNPLRYRICNNCDRPILQSCLSKHIKICNQIVKVEKL EEDDKPMNMVRKRKNQVLEESKESTPVTNTNSTNSSNAINSTTSKKTKKVKLPKEKKPKKERVKSTAKPKGPVDVERQCG VPLPNGGYCARSLTCKTHSMGAKRAVPGRSAPYDQLLVAYQRKNQAKFAANAAAAHAARDDLIHGSQIPIDEDDEAHQVL DGVAKSYPLPLERKVIMPARSRSSFLRMREMFAGAILPRVPTNPFGNLYSRTAVIDVDRAGDYYFSVRASPRMPNQQQNK TQKNPQPPRPQVQQQQQAQKSQQSPPQAQQQISQSAGQQTSQTVQRLVQQQQRLQQQRQQTQIQQQQQHQQQQQQQQHQQ QQQQQQQQQQQQTHMLQQQQQQQQQQQMLLLQQQQQQQAQQQQSPPITHQSPIPDNRPSNQLPQQYSQMTPQQLQLQQQL QLQQKQKEQFRLQQQQHLRNL(UNK)MR(UNK)TPQQQQQFANLTPEKRAQFQRMQLVQLQQQIKNQAIQNQMQQQQQQP SHVQSQAQTQFQQAQLKAQSRAQVLQAAQRQMQNSPTSPVTSMSSPLAIPSNLANQGPNQTSQLPNEQLSNPLMGNQFQG QFNQYQPNYRENLEGGGGSMDEKTTGWRGGHVVEGLAGELEQLRARLEHHPQGQREPGGSHHHHHH C4QZ39 Spt20 Komagataella phaffii (strain GS115 / ATCC 20864) GS115 / ATCC 20864 0.059530578 1 LEVO MSQIQSSQVGAKNMQTAQPQAQQRPINGSVTLSNGQRINPQNLTPQQQRLLQQKVLHQKLKNYKFAETSEEILHKYEKFP PSLTFHIHENHYRFGDQDGVIPKNSSVIKAFLEYVAREEIPPALIEVTKDAGVQLYEGCIILRIYDHRHLVAHINDAKDS QHVSSESSANNTNNEKKEPSKVPKTYTTILRPTQLSLYADLLYQTDYLQVRFTDSLSLNIETEILTASKRNLDLSVPLNP HRATANLKPEVKYPYYDPETDTVVHEHRPDARGNMVNADTVDYRKLHEDMAQHGSDYERLMLLLSDRFDDDSQTQGSSVT SSQFMRLRFVEAWRKKEERLQESGGSSQRQRPLQPGQIPGMLSSFSSNTGNMNTMLDNLTPQQKAAIQQRMIQQGRAQPQ QQQPDQEQLQEQQQQQPQQAMSQQRQQQLQQLYQRQQQHNQHHQQNQDELSSLDDKKIKKPPAKKQKKMTKKEMTTLHQN VAGKTIPSAESTPPTTAANKKRGTYKKKNKYILIIND C4QZ05 Subunit of the SAGA and SAGA-like transcriptional regulatory complexes, interacts with Spt15p to act Komagataella phaffii (strain GS115 / ATCC 20864) GS115 / ATCC 20864 0.039030105 1 LEVO MTDAKDKDHKYRYRMEIQQMMFVSGETNDPPVETTSLIEDIVRSQVVEIVLHSSQTALSRGTKSIVPEDVIFLIRHDKAK VNRLRTYLSWKDVRKNAKDQQSGDLADIGGDDLLDNSTSQVAASGAPGAPGSSSSTSMDSKMLSKYKKSKIRLPWELQFV FTEQPLDTNEDDAEDEDERAATLASLKRLKTNDERTKNMTKEEYVHWSECRQASFTFRKAKRFREWCGLSHLAESRPSDD VIDILGFLTFEMVCSITEEALIVKMLEEQNGDLASSTTTIQKLQESHRKRKHLFDGPDKDVRPITSGHVLEAWRRLQKRN VEKKAIRNFQGGKLRSRVQLI C4R3E4 Subunit of the SAGA transcriptional regulatory complex, involved in proper assembly of the complex Komagataella phaffii (strain GS115 / ATCC 20864) GS115 / ATCC 20864 0.136768828 1 LEVO MANERALQYFVTSDNQRLYDLAAKLFSLGFFNCYFTPQQFQLLSVILDNGKLRIEEDGFVSTVWDEFIKGRLVLQFSKGD YEKESTKHTVDNVKGTDDKTGIEVSKENGHSSDPPSADHDITESDNVGREETLDDQFSELYLKDGVSTSQFMCAKLRYLL FEQAIDYLYTNSSMNGDAEEYSLLQNVDDMNEEKEETAKPATPQNVREIDNDYDDDEDEDEEDEEIKEASSKNPFKTEDN EPLTNERQPTNNVFIRLCSDEKSLSKSLTLNLLTSMVTSKPEYPVEQLKGSEVIGTSHPLLGTASAIESKLEKRNEARLI KNFSKIYHQFDKDERNFLKRRKLEISNKQFLDQDNNDPKDRPSSNSTSDEESNSNNLEKTSQPSSVNKLMQLGGAANLSL KNLLSKVEENREKLNLSDLDLRSLIMDVRKNRSKWASDDKIGQEELYEACEKVVLELRGYTEHSTAFLNRVSKREAPNYY QIIKKPMDLNTVMKKLKSFQYKSKQEFVDDLMLIWKNCLTYNSDPSHFIRVHAVAMQKKTLSLIPLIPDIVIRDRSELEK DEVENVVETPQSSSIGTPMTTRVAGGKGPKKGRTHREPPTRPETPDGIAGEDSSQVSKAEQDSPAKALEVTENDSTKEKE KDLSDVPTQEQKNDKTEKDDDYQEAVEDEEEDDDDNTNLEEDSTEDEDDLEVQTWNSLTSNVRYKICEKRRNLFKENKIQ PNEEAIFRDTYQMENFMHYLGDDVRIVLNTPMSRYQYYDGNEDPYLIEYDISGGIPGLKYSGVSPDEGDLEDNMLVDQLM KGESSIRESGFARKPTGMNKKFNEIIHLMQQIRRICFKISLIRQMQTQQFLHHTQMKPPDINEIQDIDIDQLSNLPNRDK LDSDVSYNSLKRSISKILMANGFESTAPFCSDVITQIAENYFGNLVKTLKNHIESKSINKVMGDAKFQKVSNKDILLLSL LENGVESPDALYEYYNENIVKQISKLEGLKSRLSSFLAELLRPGLQDLNERQFNDNSDEFLTGNFSSEIGDDFFGFRELG LEKEFGLLTSTVPLHLLHSRLNSSIFNSNHEVSQLKFDDIQAEEKEQLYKREIPQHIKLIQPFLYNIAEKSKTIHYKQLK KLNELQKMPENDDDILLIEDEDLPLKQRNTRPRVPPTGKIPNVKKKAVNGAYFLDPAIFSSNNQVKVEGDT C4R5C7 Transcription initiation factor TFIID subunit 10 Komagataella phaffii (strain GS115 / ATCC 20864) GS115 / ATCC 20864 0.023879145 1 LEVO MSTEKLFEDLDEDSLMQDVEGGVEGSMTIEEEPEPNDEKEAPHISMPSLPEYTRKDKTLEEILEMMEDEEFTPIIPDAVT DYYLAKNGFETSDIKIKRILALATQKFISDIAQDAYEYSRIRSSSSVYTSANPQARARQLVAGQQQQQQQQPQQQQQQQP QTGASQPAPTVGGSGGGGGGGGGTSTGTNNKVVLTMDDLRSALGEYGINVKRPNFYR C4QXP2 Subunit (61/68 kDa) of TFIID and SAGA complexes Komagataella phaffii (strain GS115 / ATCC 20864) GS115 / ATCC 20864 0.066690133 1 LEVO MNQPPNQPQDNDSQVSSSGMQGGNSMNYSSSAPVNGAGQGPQPQQNSQGQNGKKPVGMQQAQIQLLARRYQLEMQKAHQL GPQTPQGAEHLQTATKIKHVLLSYQQQRQRQQGQVQGQGLSQPQGQNQAQGRVQQQTQGLSPDPGSHQGSPQFQQPHQVM MGSAQTAGTSIANPQAQSNISSQVSQMAAAKVNSASPPIPPKTVGTPTGTPVGTQPRGQVTIQQFQQVKSILEEFEKKLR TIEAAKRDQNLPEETLQKLLRQEAILKQRYAQTKATAYQMSQHLQRQQQALRAASAESAEVYVTGSASSPNMNVYNQQIL TQQPQQQLQQQQLHQPQPQQPQPARQSPHLLIHQQQQQQQQQQQQQQQQQQHPVTHRPSNVSQTMPQPSQPLQSSTPSSA VGRNQSPGATPVTSVNAAAKPSPGTSSTSTLINQHILKPAPPPTEIPARLQVKPPQPAAMKIPNRPTLLGGSAISQPSLT TPVSIRPPPLEMEGDHVLQKRKLKELLRNVGADEGDGETVIDGDVEELLLDLADEFVTSVTSFACRLAKHRKVDNIDMRD VQLHLERNWNIRVPGYASDEIRSVRKFQPTAGYNQKVQGVAISKSVNKN C4R150 Subunit (90 kDa) of TFIID and SAGA complexes Komagataella phaffii (strain GS115 / ATCC 20864) GS115 / ATCC 20864 0.080933008 1 LEVO MKQEPGDSSDKSAPSGSITPQPKPPQQANVSNQQPQKPQQFSAADLNRIVLEYLNKKGYHKTESMLRMESSHIPAPPTNI PTPQTTNISRPTAPGRAPEYSDDPATIKRGYSILKSWCESSLDFYRPELEKFLYPVFVHCYLDLIARGYPSHAREFYDKF SKDHSVLHEYEISKLGGISLKEHLQENDVAKIFRSHKFKVLIGRTTFNLLLYFLNENDAVGGGVVLRLINQYIEPVITTE AIAVEREGELNLSEGIVELHTLNNTSIGGEQREISSVDAFNKKPVKLGKLQVDPEYSKELEAELKLKDEHEQAAQKKVST TLLEEYRENFKVDPSDENNPSKDTLPLPLKSAQDLRNDIAMIQDSRAKIKLSAAQASLPSVCMYTFHNTNNDLTCLKFND DSTMVASGFQDSFIKLWSIDGSPLRSLLKNDPYNQQNNDGVAVKGSRRLVGHSGAVYGVDFSPDNRYLISCSEDKTVRLW SLDTYTCLVSYKGHSSSVWDVKFSPMGHYFATASHDQTARLWSCDHIYPLRIFAGHLNDVDCVEFHPNSTYLFTGSSDKT ARMWDIARGECVRVFMGHSGAINCLAVSPDGRWLASAGEDSVVCLWDISTGRRIKAMRGHGRSSIYSLAFSREGTVLVST GADNSVRVWDVKKNTNSPSAQPEPINDVTAQGIQKKTEDLRRRKEIVATNDHMSVYFTKKTPVYTVHFTRRNLCLAGGVF GG C4R4L4 Subunit (60 kDa) of TFIID and SAGA complexes Komagataella phaffii (strain GS115 / ATCC 20864) GS115 / ATCC 20864 0.054888444999999994 1 LEVO MSKNSQRSSIPTSHTLWSPSDTVKDAAESLGIFNLNEEAAKNLAMDIEYRIHEILDQASKFMRHGKRRTLHTSDIDRALK VLNLEPLYGYDVSRPLVFKEALVGAGQNLYYVDDDEVDFEKLINEPLPKVPRFSTFTAHWLAIEGVQPAIPQNPSPNDIK NILPINRGSMENMFSLINDEVKEDTNEEFTSTGPSVSSNISNQKQGLEVKPLVKHVLSRELQLYFDKIVEVLLNQEETKE AELLRNSALQSVRADPGLHQLVPYFIQFISETITKNLKNISLLSTMLELIYSLLMNESLFLEPYVHAIIPCILTLLLAKK IGNVDDELQKQQQLALRELSASLLERVIEDFGSSYSTLKPRITRTLLRAFVSVNNTTPGTQYGALLGLRGLGSEVIRIVV LGNVINWSSTFLEKLQQEDQVFLIDTLIETLRVLTKEGKLVKDMKTENGIDNERLKQRVGDLIADRIQACDDAQDIYWGI FFGEV C4QW33 Subunit (17 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation Komagataella phaffii (strain GS115 / ATCC 20864) GS115 / ATCC 20864 0.017303576 1 LEVO MTNEQAAIPRDVRLLHLIFATQNIYSYQDHVPLQLMDFAYRYTTGTLQDATIYSDHAHASGSHISNAGNAGTNAQLTTED IRLAIAARTNYQFKPVPPKELLLELAAERNKKPLPAVIPTWGIRLPPEKYCLTGKDWVLEDEEEAVSYKKRKT C4QZS5 Transcription-associated protein Komagataella phaffii (strain GS115 / ATCC 20864) GS115 / ATCC 20864 0.43805534399999996 1 LEVO MLHVVQLDDFATRLKAAEDYQSKHSVLSEICDSLETFNAAQDYEYFLKSLIPLFIDVLKEVPVSFVANSPENKLRNITLE ILHRIPANDALQAYSNEIVDTLMDLLKVENELNGILCMKAITTLHKTFKASLQEKVHPFIDIVIEIYSNIPQVVEEQFNG NQIDSKENVDSTSRPNSPSFSSQSDDSKQLAQAMFSFKTLAESPITMVSLYSSYKELAASSLGNFIPHVMKVLSLEVAKQ AEARKAAEEKGIILVNVCKEITNRANYGEFIIGQVKAASFLAYLFIRRQAQTFLEPYQQAIPDIIIRLLQDCPSELSAAR KELLHATRHILSTDFRKMFIPKIDLLFDLRVLIGEGFTAYETLRPLAYSTVADFIHNVRDHLTPAQLWKSVSIYCKNLQD DSLALTVQIMSAKLLLNLIEKIMRSESKTESRQLLMVIIDAYTKRFKMLNSRYNGIMKQHATYEKEKQEKQNQERLLTNK LDGTTPSPSDDKKVELIDEDQDVKMEDPTPEISDQETIKGDNDASTEPQDSEQQLADFMSLQEYLPIQVSVPPEIDLLKD SRYLFKTLMTFLKTIMIGLKNSNPPSSQNHFNAQNWNETARGFSNEDINILKSLFRECILALRFFSTSKTSLPASSMKQS FDITGPNLPITSTKEEKDLMEIFATMFIHIDPASFNEIVREELPFMYKQMLDFASLLHIPQFFLASVITSSSFSGILITF LKSKLVDLGEVNIIKSNILIRLFKLCFMSVSLFPAANESVILPHLNELILKSLKLSTTAKEPLVYFYLIRTLFRSIGGGR FENLYKEIMPLLQVLLESLSKLIHEARRPQERDIYVELCLTVPVRLSVLVPHLSYLMKPLVYALNGSQESVSQGLRTLEL CVDNLTAEYFDPIIEPVIDDVMEALSKHLKPLPYYHQHSHTTLRILGKLGGRNRTFIKPVDNLKTDSELFQNVEAMFKIH GLPNEVPLSITPGLSAAFSLLTDPRPRIHYRINSFKYISGIFQLFLGATQLPDDYANRLKESMDIILEDTIAPDEPLNKL HHFPVKDIAKYDSQMELLVKLLESIFYAVSLQEVREESKALIRGTCNHFILLYFNKMVIDKRKFVRKFSVDNHEGNLFLN ENCIFDAIIYALSSDNSAVRSMGLESVQLIYDSCVELFGNIDCALKFAPLNVMCSKFIHCCFEEPYHKKLAGCIGLEMML NSLDIPMKYFNARQLEIIRALFYVLRDTAPELPCEVTNTAKRLILNSLKEWNKELTRNDVFSSVFQNLVSSLIVDLPNAN EIVRATAQEALRTLSETTQVPIATMISPCKHILLAPIFGKPLRALPFQMQIGNIDAITFCMGLENSFLEYNEELNRLVQE ALALVDAEDESLVSAHRISEHKTSEQLVRLRVVCIQLLSLAITKPEFAAAQQRSNIRVKILVVFFKSLCGRSIEIIRAAH GGLKAVIDLKMKLPKELLQNGLRPMLMNLSDHKKLTVASLEALSGLLKLFISYFKVGIGSKLLDHLLAWAQPRTLQQLGS QDLENNSTVQIIVAILDVFHLLPPTAHKFMNDLMNALLYLENNLHRCQYSPFREPLAKFLDRFPDESFEYFFNEFSKREI TTRFVYFVGLDSCSSLRAKVLESLPRVRGLLHQEGSAEEKCVRFSNLVDLCESLAASDKEWIKDKEELLGELLDAGSVCL TLKRSSNVVSPLYFQVDQGFETLQLLYIEYFKSQPLGHEKVFNFIDKISKEGLPFVLEFDDFIFNEVVKCQDIPTVQQTL DTIIRMTPQVSSLDARVYLYKRIFLPICIYESEMHGDLSRLSQTENNELPAWLKSFDSDVWKATGPLVDDYTSTLEDRYR LELMQLTALLIKGAPTALTDMRKDIIKFSWNYIKLDDNTSKQAAYVVTAYFISRFDTPSELTTRIFVALLRCHQIDTRYL VKQALELLAPVLSERTNSELDWLKWPRRVLSEDGFNITQVANIYQLIVKFPDLFYPARDHFIPNIITAMGKLTVMSNTSL ENQQLAIDLAELILKWETKLPKSEKLGSAEETEKEKSVSEDKMDIDVKEETKEDIAERPKAEDQIGGDDSDSSNILTSED YEVSFAQREACVTFLIRYICISTQRPSENELGKRALNILYELLGPKYWSEVTVKLQFFERFLMSSDLNQPSLLGYCLNAL EVLAVALKWKPTTWIIENVSYLQKLLEKCLRSDNQDIQEILQKVLGIILEAINKETQGSEEDEPEEVTNFISLIVNIIGE DLSNMTSVAAGVSLCWTLSLYRPNALDSLLPSIMRTFNKLCRDHIAISLQGNQPQSGDFANIEFEAKVTTNLLEKILNLC AARISSLDDQRRVFLSLLAQLIDRSVDKDMLLKVINIVTEWIFKTDFYPTTKEKAGILGKMMIFDLRGEPELSKKFNQVI VDIFESKELAHTELTARMETAFLFGTRLSDVSIRKKLMSILSDSLELDIDKRLFYIIKDQNWEYLSDYPWLNQALQLLYG SFHLDSPIRLSPEENTLSPLQSITEGLAREKSPVEKAPQNIIDFVAKHNEFLDSVRSLTAGDILNPLIDISYQSAETIHN AWVVVFPVAYSAIESRYELEFTRALVKLLFKDYHIRQQDARPNVIKSLLDGVGKCPGLHLPPHLVKYLGSNYNAWYGAIK LLEELSEGQGIDNQKISDANQDALLEVYMSLQEDDMFYGTWRRRAKYFETNAALSYEQIGIWDKALQLYEAAQIKARSGV FPFGESEYSLWEDHWIYCAEKLQHWEILTELAKHEGFTDLLLECGWRGADWIADREPLEQSVKTVMDIPTPRRQIFQTFL ALQGFSQQKDTLQDVSRLCDEGIQLTLRKWNALPQRVTRAHIGLLHTFQQYVELMEASQVYSSLVTTNAQNLDVKSQELK RVLQAWRERLPNVWDDINIWNDLVTWRQHVFGVINRVYMPFVPVLQQSNGTNNGNSYAYRGYHEMAWVINRFAHVARKHE MPEVCINQLTKIYTLPNIEIQEAFLKLREQAKCHYQNSSELNTGLDVISNTNLVYFATQQKAEFFTLKGMFLAKLNAKDE ANQAFATAVQIDLNLPKAWAEWGFFNDRRFKENPEEIFHAKNAISCYLQAAGLYKDGKTRKLLCRILWLISLDDAAGSLA KTFEDHHGESPVWYWITFVPQLLTSLSHKEAKIVRHILIQIAKSYPQSLHFQLRTTKEDYQAIQRQAMAVNRAEEQSSNK QDTADSVLKNTNTPQPQTRTETSGTTAESDKKPSIPPKEEQGSPQPSRPATTQASPQAQSQENGESSQKHPPEIPTTDSR QPWQDVEEIMGILKTAYPLLALSLESLVDQLNQRFKCNADEDAYRLVIVLYNDGVQQMNRVANPREEVKLPAATEASISR FADSVLPKNIREVFEQDIIACNPNLETYISKLRKWRDCLEEKLDRSYGKADLERVSLHLSLFHHQKFEDIEIPGQYLLHK DNNNHFIKIERFLPTLDLVRGSNGCYKRMTIRGNDGSLHPFAVQFPAARHCRREERIFQLFRIFDDALSRKVQSRRRNIS LTLPIAVPLSPHIRILNDDKRYTTLMGIYEEFCRRKGQSRDEPFAYTIQKLRAAFDPRLPKPDIVSVRAEVLASIQSTLV PSTLLKDYYTEKFSNYENYWLFRKQFTAQYASFIFMTYIMCINSRQPQKIHINEGSGNIWTSEMLPTKVATGKTHSTAYN NSTLDPAVKAGAPIFYNTESVPFRLTPNIQKFIGEAGLEGILSVYILVIANSLSDSEFDMEQYLSLFVRDEVISWFAQQH RASAQTNQLREIVRVNVELLTKRVLQLNHIPNSQNVATQFVLNLISQAVNPRNLAYTDSAWMAYL C4QYV4 Transcriptional regulator involved in glucose repression of Gal4p-regulated genes Komagataella phaffii (strain GS115 / ATCC 20864) GS115 / ATCC 20864 0.08186430499999998 1 LEVO MAARSSTRRGGQPPGVAKSLGSNKSSPVKKGLGAGKGKPKVDYPKQNPSSTLHDILSELNLSYDSNLGLLQGDGIAFPPS VSVLNNVKGLFEQLIEELQYVSNYDDNLLKIIDNKLKEIEHKPSTGEVKEEEIDGTESEQPARKRQKVQSTDRIEIPDTK PQGLPLKESSSQKVDSKTSVKDEAKEDEIGDDNDDDDEDDAMEEDEAGDDDEDEEEAEIEGEAGIGGEPGAEAAVEADDD EEDEEVEEEEAASEAKPVVKEGFEQEGHYTRENDTRVKNPKSEFVTSQTLPVAAVELGLYDENGLEQTGEDYYKRKYGVA SYPTSDLKEFLPGELPDEDFTKSKPPSQVQFSTFQSYLEPYFRPFTEEDIKFLKKQYNLPQNLPKNYDPNVTPFVIPKFG AHYRDTWYEEDINTGMIKKKPNDVDPRLADQKMRQDALIPKGSGASLTDDVLETEKVSCGPLASRLLSALLKNGDDTEDG EPVDNDDNNNVSSAIGNEGWTPSVETSDYETLDQRLRRELKYIGVFMNVEQTLKREGHADELVNSVGVTSGNGEFEEDWL NSREDDEISAEMRSLQRELRRLTRKNVRRKEKLIPIVEEQLAWQEYQSILEDLDKQVDQAYLRRIRVPRKNKRKNESQSS GQQTQQQQQQQQQQQQQDQQQTGFKALLDKRTRWIEKIGPLFKPPHLMRRPPSESVFKDVDLENDDEELEEDDEMKVDID LR C4R2A4 Spt8 Komagataella phaffii GS115 GS115 / ATCC 20864 0.034059902 1 LEVO (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) Polyubiquitin-B Homo sapiens 0.008560831 1 Escherichia coli LEVO MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRG(GLZ) J3QS39 Ubiquitin carboxyl-terminal hydrolase Komagataella phaffii (strain GS115 / ATCC 20864) GS115 / ATCC 20864 0.056745879 1 LEVO MTSTVKKTLEEAKFSPPVFDSCPHLKQILTSNAKDTVYRNYGLAVNVALALKLRNGNIPLYKTSDGSKVEYKKLARLRNK AVRCRECLESLSCTYFCLQCSHVGCWKNGHASAHTKSTGHVFGIDSQTGYIFCFRCGDYVGDQRLEFIRQSKQGERTEPI MNNLGTETIIDGSRPPSLKASTGLRGFINMGATCFMSSIVQTIVHNPFVRDYFLSGYHAKCTKKMDTCITCCIDEIFKVF YGTDETKGYGPTALLTAAWRVKNSLAGYSEQDAHEFWQFLLDEIHKSDTELHPELDDTSTCRCITHKTFAGQLQSTVTCE KCLHSKNTVDPMLDLSLEIAKISKDKVTLNDCLDLFTSKEKLDSMTICSHCKKETTRTKQLLVRKLPPILAFQLKRFEHS ASSSTKIETHVGFPLFLDMEPYTVSETLNSNEQGRASWGLMTYQLFAIVIHIGSVNTGHYICIIKNRDGNWFKFDDSRIT LVSQDYVSKSNAYLLYYILCQA C4QY61 3.4.19.12 SAGA-associated factor 11 Komagataella phaffii (strain GS115 / ATCC 20864) GS115 / ATCC 20864 0.013977742 1 LEVO MSSEVMQETIWDCLMSNILRQIVINNILQEQALRSSIKAISNDDQISLKEINAQRLKFVKDDKDIFNHINGKRSENKYNG TGADASNGTTDTEYFTCLNCDRKIAGNRFASHVDRCLGGRTRK C4R2D9 Transcription and mRNA export factor SUS1 Komagataella phaffii (strain GS115 / ATCC 20864) GS115 / ATCC 20864 0.011126674999999999 1 LEVO MTNSDVQHLKQQIQDVLVESGKYDELSNFLRSKLYQVGWTDEINRLTQSIVTNEAKPTFSNVIERIEPKAMDIVPEHIKT EILAKIEEFLKDVVPK C4R1P1 water 1.8015e-05 91 HOH singleParticle particle 0.4 8.0 ETHANE 95 283 FEI VITROBOT MARK IV FEI TITAN KRIOS FLOOD BEAM BRIGHT FIELD FIELD EMISSION GUN 300 70.0 0.01 1.5 0.8 3.5 4.5 105000.0 FEI TITAN KRIOS AUTOGRID HOLDER NITROGEN GIF Quantum LS 20 GATAN K2 QUANTUM (4k x 4k) SUPER-RESOLUTION 8.0 52.8 1 1068534 C1 20.0 FSC 0.143 CUT-OFF RELION 3.0 354104 MAXIMUM LIKELIHOOD RELION 3.0 MAXIMUM LIKELIHOOD RELION 3.0 OTHER