<?xml version="1.0" encoding="UTF-8"?>
<emd xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:noNamespaceSchemaLocation="https://ftp.ebi.ac.uk/pub/databases/em_ebi/emdb_related/emdb-schemas/emdb_schemas/v3/v3_0_9_3/emdb.xsd" version="3.0.9.3" emdb_id="EMD-0909">
    <admin>
        <current_status>
            <date>2024-05-29</date>
            <code>REL</code>
            <processing_site>PDBj</processing_site>
        </current_status>
        <sites>
            <deposition>PDBj</deposition>
            <last_processing>PDBj</last_processing>
        </sites>
        <key_dates>
            <deposition>2019-12-18</deposition>
            <header_release>2021-07-21</header_release>
            <map_release>2021-07-21</map_release>
            <update>2024-05-29</update>
        </key_dates>
        <grant_support>
            <grant_reference>
                <funding_body>National Natural Science Foundation of China (NSFC)</funding_body>
                <code>31430020</code>
                <country>China</country>
            </grant_reference>
            <grant_reference>
                <funding_body>National Natural Science Foundation of China (NSFC)</funding_body>
                <code>31621092</code>
                <country>China</country>
            </grant_reference>
        </grant_support>
        <title>core region reconstruction.</title>
        <authors_list>
            <author>Shi Y</author>
            <author>Huang G</author>
        </authors_list>
        <keywords>building block of vertebrate NPC., STRUCTURAL PROTEIN</keywords>
    </admin>
    <crossreferences>
        <citation_list>
            <primary_citation>
                <journal_citation published="true">
                    <author order="1">Huang G</author>
                    <author order="2">Zhang Y</author>
                    <author order="3">Zhu X</author>
                    <author order="4">Zeng C</author>
                    <author order="5">Wang Q</author>
                    <author order="6">Zhou Q</author>
                    <author order="7">Tao Q</author>
                    <author order="8">Liu M</author>
                    <author ORCID="0000-0002-9384-8742" order="9">Lei J</author>
                    <author ORCID="0000-0001-9338-8048" order="10">Yan C</author>
                    <author order="11">Shi Y</author>
                    <title>Structure of the cytoplasmic ring of the Xenopus laevis nuclear pore complex by cryo-electron microscopy single particle analysis.</title>
                    <journal_abbreviation>Cell Res.</journal_abbreviation>
                    <country>CN</country>
                    <volume>30</volume>
                    <first_page>520</first_page>
                    <last_page>531</last_page>
                    <year>2020</year>
                    <external_references type="PUBMED">32376910</external_references>
                    <external_references type="DOI">doi:10.1038/s41422-020-0319-4</external_references>
                    <external_references type="ISSN">1001-0602</external_references>
                </journal_citation>
            </primary_citation>
        </citation_list>
        <pdb_list>
            <pdb_reference>
                <pdb_id>6lk8</pdb_id>
                <relationship>
                    <in_frame>FULLOVERLAP</in_frame>
                </relationship>
            </pdb_reference>
        </pdb_list>
    </crossreferences>
    <sample>
        <name>Cytoplasmic Ring Subunit of Xenopus laevis NPC</name>
        <supramolecule_list>
            <complex_supramolecule supramolecule_id="1">
                <name>Cytoplasmic Ring Subunit of Xenopus laevis NPC</name>
                <parent>0</parent>
                <macromolecule_list>
                    <macromolecule>
                        <macromolecule_id>1</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>2</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>3</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>4</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>5</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>6</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>7</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>8</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>9</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>10</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>11</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>12</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>13</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>14</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>15</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>16</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>17</macromolecule_id>
                    </macromolecule>
                    <macromolecule>
                        <macromolecule_id>18</macromolecule_id>
                    </macromolecule>
                </macromolecule_list>
                <natural_source database="NCBI">
                    <organism ncbi="8355">Xenopus laevis</organism>
                </natural_source>
            </complex_supramolecule>
        </supramolecule_list>
        <macromolecule_list>
            <protein_or_peptide macromolecule_id="1">
                <name>MGC83295 protein</name>
                <natural_source database="NCBI">
                    <organism ncbi="8355">Xenopus laevis</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.22785414099999998</theoretical>
                </molecular_weight>
                <number_of_copies>2</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MAAQLALNSEASLWGPYREIWQTVLSALIKRQPEAVHSLDIVLKKYKPDFISLFKNPPKSAQQHERVQKASTEGIPIKGT
QRTRILEEQLIKEAFILSDLYNIGEIAAVELLLIGEQQQPTFHGLTRGLVAILLYWDGKSCMAESLLHLIQARKGKTFTL
DHSPEVVSMVTRFTDDLMEQGLTNKILTLISQIDVNNEFDKLKKERGLGNKKHRKEVSDLIKECQQSLAHSLYSWSCQTP
LNREDTLLLIGYLEKVTVEGDGSLDKVNLTLLMSLLYCLDVGFLEQGTDDREELMKQASMFMDRQYIAAIHNRLQNTQPW
KSPGMQATVRLAWALALRGISQFSEVLEFSEADEPMAEIAIGGNVFLFLTEAVVGSESFCTDEFFIRRIHKLVTDFPTLM
PMKVKQLRNRAEEDARLIQMSMQMGNEPPASLRRDLEHLLLLIGELYRKDPFHLELALEYWCPTEPLQSTSLMGSFLGVA
HQRPPQRQVLLSKFVRQMSDLLPATLYLPYLKMLRGLASGPQCAHYCFSLLKANGGSSAENLQAAGGSPVSWDHFFHSLM
LYHEHLRRDLPNTDNIHQRHPPLRGITQRELDGLIACLQLTCTIIDWSESARLALCEHAQWMPVVVILGLLQCSIPPLLK
AELLKTLAAFGKSPEIAASLWQSLEYTQILQTVRATGLRQGVGIEVELNEIESRCEEYPLTRAFCQLISTLVESSFPTNL
GAGLRAPGFEPYLQFLRDTVFLRYRTRAYRRAAEKWEVAEAVLDVFYKLLKDYEPQPEDFVDQYVELQGEERVAFKPPGF
SLMHHLLNESPMLELCLSLMEEGVTQLDTYAPFPGKKHLEKAVAYCFMLLNLTLQKENRFMDLLRESHLSMIVTPLEQLL
QGINPRSKKADNVVNIARYLCHGNSNAELAFESAKILCSISCNSKIQEKIVGDFTQDQNVSQKLMVGFVSCLDSEEAEEL
LDSEKEAEDQVKQTNIRYMTKIHILNLLITSLEMKAPNLAMFLLGYELKKPVSTTNLQDSGVLGCPRTCLHSILDILRKG
TDVRAGPVAVWDTPHLAELCYQVIYQLCACADTSGPTMRYLRTSQDFLFSQLQHLPFSVEESEISAMNQMSWLMKTATIE
LRITSLNRQRSHTQRLLHLLLDDMPTRPYSADGEGGMEDESRSLSGFLHFDTTSKVRRKILRILDSIQFSNEIPEPLQLD
FFDRSQIEQVIANCEHKNRRGQTVCNVKLLHRVLVAEVNALQGMAAIGQRPLLMEEINTILQYVVERNKLLQCLHAKRHA
LESWRQLVEIILTACPQDLIPTEHRQLIIRDLLQDLHVKILDDDAAQELMPIVAGAVFTLTAHLSQSVRTELKQPMTASG
LGQSQYVQMLDGSFAAPPGTENISAGFASIGDSSLHMILRNLLEFILKTGGGFQRVRAHLYGSLLYYLQIAQRPDEPDTL
ESAHKSMWERLTAPEDVFSKLQRDNLSIFESYGTALMEVVCRDACDGHDIGRMLALALLDRIVSVDRQQQWLLYLSNSGY
LKVLVDSLAEDDVVLRNLLTPQPPLLKALYIYESKMAFLTRVAKSSQGAIELLRSGVIVRLAQCQVYDMRPETDPHGVFG
MRETPVFIPAPVERYRQILLPALQICQLILTSSTAQHLQAAGQVLQFLVAHSDTIQAILRSQEGSLGSLQELALLTGIIS
KAALPGVLNELDIGLNDGSMMELQGHIGRFQRQCLALLNRFGGSDRLRQLSLQDDSSRLDGVSKKDDMELAMQQICSNVM
EYCQALMIQNSPSFQQTVCLFTPSLKESASRDGTRQDSQVSILPSWRLPSLGVVIHLLKQSANNFFTYYDIHRQSVGKLQ
NVEQLPPDEIKELCQSEMPVGADKISTTQKYGLARRRLVKLINSRAKLLSLCSYIIETCLYILWRHLEYYLLHCTTSDSQ
DPVFSNMTFGNRRFQDTFNTDPNMDPRNLRQNKVSQQDVDTLLREGANSFGESLQKRLLDIESLYCKVRSRHSFIQALVR
RIRGLLRVSRV</string>
                    <external_references type="UNIPROTKB">Q642R6</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="2">
                <name>Nuclear pore complex protein Nup85</name>
                <natural_source database="NCBI">
                    <organism ncbi="8355">Xenopus laevis</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.07516004700000001</theoretical>
                </molecular_weight>
                <number_of_copies>2</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MEELDVDPAETPIPGLGQQNRHIGFSWGPGDLLLYETLYQKQGNSETAARCPFMYLVRSDEDIYSPVLRKLFNESHSIFV
GLQKSAEEASGKSRKAQLVQVSRNYRSVLRACMEEMHTLSESTRETAQKYISQISILSAMELSWNLCEILFIESAPAGPL
LILLLEWVRLHVCEVDNIVQDVLRSEKPTEHEKFWDGVTGYVLQGRMNEARQLLAKEASTSASARSMCRVLDDLLKKMPM
LHTGGTQTLTEFELKWQHWREECERHLQNGTFSSNVHMEAVCRVLLGDEEVLLEKRDLMTTWYHFLVSRLLFKHPTVKPT
ELHFYAQSSLDMFLAGDSCPEPLDNILLAAFEFDIHQVIKEFSIVSSNWWFVAHLTDLLDHCQLFQAHNLYFGANMREFL
LLDYASGLFSHHSLWQLGVDYFDYCPNLGREYLKLHMERIPLSTEKKALKALRICEQRQMTEQVRSICKTMAMQSLCNRR
LGSALSWSIRAKDAAFATLISDRFLKEYCERGNFTDLDLIDNLGSAMLLSDRLTFLGKYREFHRMYSQEQFSEAASLLLS
LMTARIAPCSFWLTLLLDALPLLEQKQVIFSAEQTYELMRCLEDRMAAKLESTSPDEIQKQDSSIDNTKVEMLRLALARN
LARAIVTEGALQE</string>
                    <external_references type="UNIPROTKB">Q68FJ0</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="3">
                <name>MGC154553 protein</name>
                <natural_source database="NCBI">
                    <organism ncbi="8355">Xenopus laevis</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.041744512</theoretical>
                </molecular_weight>
                <number_of_copies>2</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MADKFAAKFVSHKISRTRWRPVSASSLQQPDVFATGSWDNEENKVCVWATSDFGATSLDEEYQGDPKQLCDIKHPGDVMD
MQFLDKERIVTGSSTGTVTIFRHHENNQTLSVNQRWEQAHYHVGSNMRAPCTAIVCSSPEIVSVGEDGRINCFRAESRDV
LRTIDDADSSTMHGVTFLRTTEILTVNSVGQLKLWDLRKQGNDPTQIFSVTGERVPLHCVDRHPNQQHVVATGGQDGMLC
IWDVRHGKMPMSLLNAHEAEMWEVHFHPSNPDHLFTCSEDGSLWHWDASADSEKPTFLLGGRSTFNISRSSIAPPNANQS
LACAWLSTDPTKGQLEITNLLPSSTLSVNSLDVLGQNLVCGTDAEAIYVTRRLFS</string>
                    <external_references type="UNIPROTKB">Q05AW3</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="4">
                <name>Nucleoporin SEH1-A</name>
                <natural_source database="NCBI">
                    <organism ncbi="8355">Xenopus laevis</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.036037664</theoretical>
                </molecular_weight>
                <number_of_copies>2</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MFVARSIAADHKDLIHDVSFDFHGRRMATCSSDQSVKVWDKSENGNWHCTASWKTHSGSVWRVTWAHPEFGQVLASCSFD
RTAAVWEEIVGESNDKLRGQSHWVKRTTLVDSRTSVTDVKFAPKHMGLMLATCSADGVVRIYEAPDVMNLSQWSLQHEIS
CKLSCSCISWNPSSSRAHSPMIAVGSDDSSPNIMGKVQIYEYNENTRKYAKAETLMSVSDPVHDIAFAPNLGRSFHILAV
ATKDVRIFTMKPLRKELSSSGGVTKFEIHTVAQFDNHNSQVWRVSWNITGTVLASSGDDGTVRLWKANYMDNWKCIGVLK
GD</string>
                    <external_references type="UNIPROTKB">Q4FZW5</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="5">
                <name>outer Nup160</name>
                <natural_source database="NCBI">
                    <organism ncbi="8355">Xenopus laevis</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.16265823399999998</theoretical>
                </molecular_weight>
                <number_of_copies>2</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MAAAERHMTPFQAIDWAGSITLPMVQRVGGFTRAIMAASVNLERSYMELIGAERETSRRNFRDLSLRPDVNLVIGGPKYA
DCAGGYCYSESSSLLSATRNRFLHWTSYADTLELVEISLDINLVNNAVRLRILNCSILPGGVHICETPNNIVVLILTNQT
VHRLILPHPSRMYRSEIISDSHIQSIFTDIGKTNFHDPSNTYVIPAIPGRAPNTTASTAWLSSDGEALFALPSISGGILV
IKMPPHDMEGLVTIAELKQSSVMQRLLTGWMPSSIRGDQGPAHLPVSLAVHTLDHDSYLFALCQDHKLRMWSYKDQMCLM
VADMLEYVPVSKDIRQTAGTGHKLRLAFSETLGILYLGVYLHTPKQGQFCVFQLMCAESNRYSLDHISSIFTNQETLIDF
TFTLTSMDIWALWLDDDNQTVVKHINFEENQAGQWNPVFVNPLPEDDLAISDEQEPQEAYLECLFAPGRFTIAAVQKAIQ
ILRKGSGRVLDLSWEELRKDVTLTVENEIQNAVIDYDVSQEEFRQINIENWCKFYTCCLQYQETLSRPLALLVHPDTNMV
CLLRKGFLSFLAPCSLVEHLYLVPAEHLLTVDESVISDDIDAASDIVNLIQCLRMIADYISEDMAYLMESACCHLQSPER
VAEQILEDLIANDIDNIMENIQNKLQDTRNPIRAIGFLLQNMDYETNADMEQPQPNTRLNLSTLYGSITASSVVCQAICK
ISATRFLICRDLLILQHLLLRLGDMALIGAGQLLHSQQELIPRAAQLLLSYYMIRWGSQCLACAVPVDILESNLQHLSVL
ELSDSQVEKRRYTSGIQTIVELFFEDVARKHFPHVFIQSGASQLQEPLNWSDLIKRITNYLLQLLWPSNPNFQFAECLMR
NCQYTQLQEYVRLLLPWCQVNVGSCHFMLAQCYLVAGEGHKALDCFSQAASEVEREDFLEKLIRVEEGESVSPRLQYYNR
VLRLLEDVGLPELVIQLATIAIGEASDDWRSQAALRTRIFKHHLDMGHNNQAYDALTQIPDPSRQLDCLRQLVVVLCERS
QLQDLVEFPYVNLHNEVVGIIESRARAVDLMTHNYYELLYAFHIYRHNYRKAGSVMFEYGMRLGREVRTLRGLQKQVNSY
LACLNCLRLIRPEYAWIVQPVSGAVYERPGASPKRNYDGESSAVPSSSQIEILELRDLEKEYVLAQTRLTLAKHNPSTAA
IAGSSAAEEMVALLVQAGLFDTAISLCQTFKLALTSVFEGLACKCIRLQQGGEAAQAEAWEWLAANQLATVITTKESSAT
DEAWRLMISYLDKYEAKNTLYHHCIINKLLSHGVPLPNWLINRYKAMDAAELLRLYLKYDLLEEAAELVLEYVDALLGKG
HQYFGIQAPLSATSQLVWFPYSAIDHLRQALGENESNQHNQAILSKLQRKMDEYFQKLKKATDDYKKLVQKPLRA</string>
                    <external_references type="UNIPROTKB">A0A1L8GIX3</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="6">
                <name>MGC83926 protein</name>
                <natural_source database="NCBI">
                    <organism ncbi="8355">Xenopus laevis</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.036588625</theoretical>
                </molecular_weight>
                <number_of_copies>2</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MKQDSASNATYTVDCEDYVHVVEFNPFDSGEAGSLLAYGGISYVVIASCRFQEEDSTVEGIEFKTLKTFHHGERVVAIAW
SPETRCDALLPLLRFATAAGDKKIRIFTSDFQDKNEYKVIEGHSGYINDLVFCSPEGTDIASVGDDHTCRIWDLDGKQIA
MFILRSPGMSVAWHPEGAFKLMVAEKTGTIRFYDLTTHQAILSLESVQVPLMSADWCVRNTLRIGAVAGNDWIIWEMPRS
SYPQDNKPAHADRARMFRWSKCNENVFATTGYPGKMKSQIAIHHLAHPQPILIGTAPVGSGLSWHRRLPLCVVGGYRKLF
FWLTEM</string>
                    <external_references type="UNIPROTKB">Q66IZ6</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="7">
                <name>Nuclear pore complex protein Nup96</name>
                <natural_source database="NCBI">
                    <organism ncbi="8355">Xenopus laevis</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.105079148</theoretical>
                </molecular_weight>
                <number_of_copies>2</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>SKYGLQDSDEEDDQLNNAEAKKLKAAPVPPQGKPPPLQQATLPGKVTPPPQSPAVDQLDRVLELDSDMADITQDQDLDSV
AEEQDITEEQEPLSASSHIASSLGINPHALQVMKASLLLEEEDGEMINRFSSFPSSMDPYPDVRSPRLFPSSHAKRTSSM
GLLQSKFASPSISRISETAQGSHSPRILPVTPWSVPAPLAPTFVIPRPAPETHLRTVGTRRQQELVPLEKSVTHGRGSLL
IDMGLFMGRSFRVGWGPNWTLVHNGDKLTERLNAEEDQNMDTIDYGFLPKPTSAKSLTESPFKVHMEKLSLEQKSRELQS
YLMPLEIELKNSSVDRSAQCPHFKPNAGVAAIHDYAGWVRNLSNEAGELEAVVKQWGLTWTLCESLWGQLKELEASLDEP
NEYVRNLERRKAFSHWLAHTAEERIEEEVSLYGPERHVEAVFSFLTGGRISDACRLAQKSGDHRLSLLLSQMVGSQEMRE
LISLQLVDWNKLQVDHYIQEERLRVFCLLSGTPVWRSSDNRSINVCSQLDWKRTLAVHLWYMLPPTATIAQALRLYERAF
QEHEEGEPYACYPLPPYLEDCSISLGDEPSAKFSSLQRDVCVHLLKLYSERQYDLCQLLDPSSVTPDPLDYRLSWHLWMV
LQALNYTHLSEHRQGTLHASYAAQLENVGLWEWAIFVLLHIPHPHIREAGVRELLNRQCVVRESPESLAKENFLIHRLCV
PAQWVHEAKAIRSRRDGDRHKEALYLLKGHQWNPCHKLVTRHLAADAVINENYRYLQSFLGELSNPEHCKHIQDWETAGK
VYLDYIRVIDMLNLIQQDESSGCELEKLHTKVMSLCKWVELIHCYTAKDRLAQSEMAKRVANILRVVLSLQQPPESMSDS
SEPRVPLRLLAPHIGRLPMPEDYALEELRGLTQSYLRELICDS</string>
                    <external_references type="UNIPROTKB">A0A1L8HBE3</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="8">
                <name>GATOR complex protein SEC13</name>
                <natural_source database="NCBI">
                    <organism ncbi="8355">Xenopus laevis</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.035315285</theoretical>
                </molecular_weight>
                <number_of_copies>2</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MVSVINTVDTSHEDMIHDAQMDYYGIRLATCSSDRSVKIFDVKNGGQILIADLRGHDGPVWQVAWAHPMYGNILASCSYD
RKVIIWKEENGTWEKTYEYTGHDSSVNSVCWAPHDFGLVLACGSSDGAISILTFTGDGPWEVKKISNAHTIGCNAVSWAP
SVIPGSLVDQPSSQKPNYIKRFVSGGCDNLVKIWREEDGQWKEDQKLEAHSDWVRDVAWAPSIGLPTSTIASCSQDGRVY
IWTSDDAATNCWTPKLLHKFNDVVWHVSWSITANILAVSGGDNKVTLWKESVDGQWACISDVNKGQGAVSTVTEGQLNDQ</string>
                    <external_references type="UNIPROTKB">Q7ZYJ8</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="9">
                <name>Nuclear pore complex protein</name>
                <natural_source database="NCBI">
                    <organism ncbi="8355">Xenopus laevis</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.105398547</theoretical>
                </molecular_weight>
                <number_of_copies>2</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MDMLSPVVREAEVSRAARRQSSNRKNPADESWSNATPTRGPSSRTTGQTLFRQHMTPQTWNSSRPPDVSAILGTVGRSPR
LLQTPGRLANLSMMSNPDDSVWTTTFSPGRTGMYTTLDSPSFTEDITLSAVMLQEEDPGEAATMSMYPDFLKSFLEHPSS
AVFELIEQYEATCNTQITLLKKIVKRVTPGQQKFSKTASILWLLQQEMVTWRLIAALYRDRIQSALEEENMFEIAAPNAS
EKTIVDKLFQRDTLVRQSQLVVDWLESIAKDEVGDFSDNIEYYAKSVYWENTLHTLKQRSMLSLGSSRPLVSELDPDAPI
RQKLPLDDLDREDDIRLLKYLFTLIRAGMTDEAQRLCKRCGQAWRAATLEGWKLYHDANINGGTELQAVEGNPYRCVWKT
CCWRMAEDEQFNKYERAIYATLSGNLKQLLPVCESWEDTVWAHFKVMVDSLVEQEIRASIISFNEANELPREYLEANWTL
DSVFEELQATDKKRVLEENREHYHIIQKFVILADVDGLMDEFSEWLSNGKNLLLGHLLRFMTHLLLFFRTLGLQAKEEVS
VEVLKTYIQRLINEKQIELIAFYVSHLPQELAISQYAVFLENITDPDQRQRCLELAKEAGLDVASITKTVVENTRKKDAG
EFAHHDFAPALDSGTSEEDRAKIDVIDWLVFDPAQRAEALKQSNAIMRKFLASKKHEAAKEVFAKIPQDSIAEIYSQWEE
QAMDSALPAEDDNAIREHLCIRAYLESHEAFNEWFKHINSPPQKPTLVGQASFTEKVAHEHKEKKYEMDFGIWKGHLDAL
TSDVKEKIYNVLLFVDGGWMVDVREDTEEDPERSHQMVLLRRLCLPMMCFLLHTVLHNTKQYKDCLRLADIVSSENQKLY
TVFSKTEMRNLLQKLRESSLMLLDLQLDPLGYEIQS</string>
                    <external_references type="UNIPROTKB">A2RV69</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="10">
                <name>outer Nup133</name>
                <natural_source database="NCBI">
                    <organism ncbi="8355">Xenopus laevis</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.12755125</theoretical>
                </molecular_weight>
                <number_of_copies>2</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MFPSPRAQGMGSARRPFNSRLTGGRKALGPGVTASSSPSALYSPVGRRVSASGARSTPSRVYLHPAASETVNYNVQLFGS
SLPVKVMEALSNASADEPMAACIHEGGWAWLACNDRLIIWKISHSSSAKLMVCKELPLPLSDSEWSADLVDICAQTGDPA
AAQSVALMAATPEGSSRYWPNILHEGTYIESYTEFGSSLCAFVTAVKGNSFILSSEKNQLVRLTPDASGKMNQRVLPQGQ
GMLSGIGRRVSTLFGILSPAVESTLCSVLWDKGDCFYTLTDSSINKWDLDDTSESQVLNWDMSRVLREYISDAIWGSESD
YDDIKAGININYLSLNQNCDGLVILSAAWHPGDNPCQIYYTLVTVKDEGYNISDEITVEVTQFNPVFQARGMQLCQLVVP
NFSSQACYLYTQEMIFACSTGTGRSTLPQEKIPFEAQGDNIVGAGSCEGWPVFFIRKSGMLTVVARETASVLPEHMEESL
SSVSKSSRQAVVKDSRPDQIAHDDKTKHLKAAFLRYCRKDILGAQSMVDSLFSDSDMEPDDELDLAVNQISVDLIDDYPA
SDPRWAESVPEEAAGFSNTSLILLHQLEDKMKAHSFFVDFLHQVGLFSRLSTCQTKGMLVATRLLLSEHAEKLSAAIVLK
NHHAKLPVLVNSAIQLALDKRMCTVPQNLTAADVYFREVSQMEIIFECLVDKEEADLESTSIDSVEWANIVVNVNTILKD
MLHVACQYRQSKNSLYKNESGIQEPEHVPWTASSGTAGIRSVVTRQHGIILKVYPQADSGLRTILIEQLAALLNYLLDDY
VTQLKSIDKLANEERYNILEMEYAQKRSELLSPLLILGQYAWASNLAEKYCDFDILVQICEMTDNQSRLQRYMTLFAEQN
FSDFLFRWYLEKGKRGKLLSQPASQHGQLAAFLQAHDHLSWLHELNSQEFEKAHRTLQTLANMETRYFCKKKTLLGLSKL
AALASDFQEDVLQEKVEEIAEQEHFLLHQETLPKKLLEEKQLDLNAMPVLAPFQLIQLYVCEENKRANENDFMKALDLLE
YIGDDSEVDVEELKLEILCKAIKRDEWSATDGKDDPIEATKDSIFVKVLQNLLNKGIELKGYLPKAETLLQSEELNSLKT
NSYFEFSLKANYECYMKMQS</string>
                    <external_references type="UNIPROTKB">A0A1L8H1I9</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="11">
                <name>Nup358 complex, clamps</name>
                <natural_source database="NCBI">
                    <organism ncbi="8355">Xenopus laevis</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.32278434399999995</theoretical>
                </molecular_weight>
                <number_of_copies>4</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>MRRSKAEIQRYVENAQNSASSPREKSMKGFLFARLYYEAKEYELAKRSVSSYISVQERDPKAHRFLGQLFEIEGNVEKAV
GCYKRSLELNPTQKDLTLRIAELICTLNIKDGRAEYWVERASKLFPGSPEIYRLKEQLLSSQGEAGWNQLFDLIQAELFA
RPNDVYVNLKLVDLFLSNQRLEEAVLHCLKPERRALRTDIEWCSCVVRVFKEYLASKQGQKNTNMRMITKELLLAQCDVV
FLTLSKKDVQKSKEALERFDQALLSVKQSVSGTDASDLSVTFYEMRGHYYMHAGTLLLKMAQSCEVQWKALIEPAALCYL
LAYQVPKPKSKPVKGDDNGQGFLEELAFDRQSKSGHLLLTLSHGKQNFISEIIETFANQCGQSILLKFLFEDNLSMQDSF
MGSDDISYVENRVPDLSELSQHDNGSLRIHNGDLQHLTWLGLQWHFLSTLPPLRKWLKQIFPRVPQETSRLESNIPESIC
LLDLEVFLLAVVQTSYLQLQDNNTTADPNRPRCLPLPICKQLFTDRQRSWWDAVYSLITKKALPGTSAKLRSVIQHDLTT
LRAQEKHGLQPAVLVNWARGLHKTGYSLNSFYDQKEYMGRCVHYWKKLLPLLDLVKQKKSIPEPVDPLFKHFHNKDIKVS
EVKDLEDEACIAFATLDLVDGKTEDAIIAFESVKNVVAYWNLALIYQRKAEEIENDCLPAEEQEEFQECLLKCKGFLKMI
CDEYSAYPSIATSLPVPVETVFEMLDSVKQSLGEAMDDHSPAFMENHSVLTTSAIKHSTPSPTKLTISPSKSARFSPKTP
PRWAEDQKSLLEVLCNKVEALKKEVQELKHNNSNANVSPHRWPNEGFESDTVADSYQGTQNFYTVPLTVSTSGPAAYYGQ
SPAYNSQHLLRPAANITPTKTSVYAMNRLPPQQHMYTYPQQMHTPPTQQSSAGCVFPQEIYGPPLRFESPAAAILSPHNE
EFYNYNVPPASTNPPLPEPGYFTKPSTAMQHSKQEVPKVSDFGKGCLGQSTSEGQKPSPFTVPMQSTPASSTFKFNSNFK
SNDGDFTFSSSHAGASSAYTGSESLLGLLTSDRPTQEQGKKSDFENIASDEKNMFRFGEKSFSPGFTVTGTQSQDKNPLV
FGQSENIFTFKTPGKSTFKPPTFGTQTKDAHNHSVESDAGSEHVADDDGPHFEPIIPLPEKVEVKTGEEDEEEMFCNRAK
LFRFDAETKEWKERGIGNVKILRHRLSGKIRLLMRREQVLKICANHYINADMKLKPNATSDKSYVWHAYDYADEMPKPEQ
LAIRFKTVDEAAHFKAKFEEAQRLLAMAEAPAISAQHKNAKDNLKLDASKVKEAPLPFGSQFILKRGEWQCDCCLATNAP
TSTSCVCCQTPNKNKSSSISSVCISAPSFTFVKESATNKLAFGQQLLKDKDQWTCSKCSQKNDAGVSHCSSCQTQSQAKA
GISQPNIASSGFTNNTSAQGDNLAAVFGKKAGQWDCDVCYVRNEPSANKCISCQNTKPLSKVSGTQAASFSFAAGADNSQ
KNFGAQFAKKEGQWDCDACYVRNEPLATKCISCQNTKLLSKTTGTQAASFSFAAAADNSQKNFGGQFAKKEGQWDCSSCL
VRNEASAPNCVACHSANPQITNKDVVPPALTPSGFKFGHNAEVGKTQQSLSAMFSCKQGQWECSTCLVINDAAKDTCAAC
QAAKPGSSASQSKEVPSTFGIKANSSQNFGQPAAGFNCGFSAKGFKFGISDEKASASNFTFKAPATNEETKMVKDGFNFP
VSAGSLSFKFGISEPDKTKEMSTGFMKGTSTNNKGSETAETTAQAEKIQQSPDKVLGQSVQSFSFADIAKSTEGIEFGKA
DPNFKGFSGAGQKLFTSSNQVNASNAQEAADDLYKTEERDDIHFEPIVQLPDKVDLITGEEDEKTLYSQRVKLYRFDATS
GQWKERGVGNLKILKNEVNGKLRVLMRREQVLKVCANHWITTTMNLKPLTGSDRAWMWLANDFSEGDAKLEQLAVKFKTP
EQAEEFKIKFDQCQCLLLDIPLQTPHKLVDTGRTAHLIQKAEEMKTGLKDLKTFLTDKAKPLDDSNAINTTDLEKQALAD
GTEPTYEWDTYDMRGDAHEETLDDSVYASPLASSPEKKNLFRFGDLSTSGFNFSFQPEPSPSKSPTKLNHSRVSVGTDEE
SDVTQEEERDGQYFEPVVPLPDLVEVTSGEENEQAIFCHRAKLYRFDKDSNQWKERGIGDLKILQRLDNKSARVVMRRDQ
VLKLCANHRITTDINLQPMKGAERAWVWTAHDFSEGEGKVECFAVRFKLQEAADLFKEVFEEAKEAQAKDCLLTPVSSRG
TTPRAASCGKAAIAILEETTKERTDQQPEEDTSLTEASTPSPTDQPAKALVSPANFTFGSDVVKNIFGSEKQVPFAFGNT
SSTGSLFGFSFNASQSQGQQVQKQPPKVTLDFNATFKDAETTNALQKPSQSSGQSPIVSSLSSSSSSSSSTLMQPMPARD
KAADVPDADSSSDVLIVYVATPTPEQKALAETLLLPLTFFCYKNKPGYVSDESDIDDEDFETAVKNLNGILYTEDKKDKA
SSRLSGCSKEPTAESDQDCIIVWEKKPTPEEKAKADSLKLPPTFFCGLGSDTDEDKDNLEDFDTEVRKVKEAKGVPEADV
TSSPEAAIVSAAETSVSLPPKQEPDSTTSISQEPVDLSSKQELPKTDSKGFSTPSFSFGLGEVSGVSFADLASTNSGDFA
FGSKDTNFQWANTGAAVFGTLSQNKKGEDADGSDEEVVHSDDVHFEPIVSLPEVEVKSGEEDEEILFKERAKLYRWDRAV
GQWKERGVGDIKILFHKEKGYYRVLMRRDQVLKVCANHVISTEIKISTLSTSNNSLVWTATDYSDGEGKVEQLAVRFKTK
ELTDSFQNKFEECQHNLQEESNPQH</string>
                    <external_references type="UNIPROTKB">A0A1L8HGL2</external_references>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="12">
                <name>Nup214 complex Coiled-coil region 1, helix 1</name>
                <natural_source database="NCBI">
                    <organism ncbi="8355">Xenopus laevis</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.005890252</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)</string>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="13">
                <name>Nup214 complex coiled coil region 1, helix 2</name>
                <natural_source database="NCBI">
                    <organism ncbi="8355">Xenopus laevis</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.006826405999999999</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)</string>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="14">
                <name>Nup214 complex coiled coil region 1, helix 3</name>
                <natural_source database="NCBI">
                    <organism ncbi="8355">Xenopus laevis</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.006230672</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)</string>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="15">
                <name>Nup214 complex Coiled coil region 2, helix 1</name>
                <natural_source database="NCBI">
                    <organism ncbi="8355">Xenopus laevis</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.0026562649999999997</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)</string>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="16">
                <name>Nup214 complex Coiled coil region 2, helix 2</name>
                <natural_source database="NCBI">
                    <organism ncbi="8355">Xenopus laevis</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.002996685</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)</string>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="17">
                <name>Nup214 complex Coiled coil region 2, helix 3</name>
                <natural_source database="NCBI">
                    <organism ncbi="8355">Xenopus laevis</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.002230741</theoretical>
                </molecular_weight>
                <number_of_copies>1</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)</string>
                </sequence>
            </protein_or_peptide>
            <protein_or_peptide macromolecule_id="18">
                <name>bridge domain</name>
                <natural_source database="NCBI">
                    <organism ncbi="8355">Xenopus laevis</organism>
                </natural_source>
                <molecular_weight>
                    <theoretical units="MDa">0.033293948999999996</theoretical>
                </molecular_weight>
                <number_of_copies>2</number_of_copies>
                <enantiomer>LEVO</enantiomer>
                <sequence>
                    <string>(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)</string>
                </sequence>
            </protein_or_peptide>
        </macromolecule_list>
    </sample>
    <structure_determination_list>
        <structure_determination structure_determination_id="1">
            <method>singleParticle</method>
            <aggregation_state>tissue</aggregation_state>
            <specimen_preparation_list>
                <single_particle_preparation preparation_id="1">
                    <buffer>
                        <ph>7.4</ph>
                    </buffer>
                    <grid>
                        <model>Quantifoil</model>
                        <material>COPPER</material>
                    </grid>
                    <vitrification>
                        <cryogen_name>ETHANE</cryogen_name>
                        <instrument>FEI VITROBOT MARK IV</instrument>
                    </vitrification>
                </single_particle_preparation>
            </specimen_preparation_list>
            <microscopy_list>
                <single_particle_microscopy microscopy_id="1">
                    <microscope>FEI TITAN KRIOS</microscope>
                    <illumination_mode>FLOOD BEAM</illumination_mode>
                    <imaging_mode>BRIGHT FIELD</imaging_mode>
                    <electron_source>FIELD EMISSION GUN</electron_source>
                    <acceleration_voltage units="kV">300</acceleration_voltage>
                    <nominal_cs units="mm">2.7</nominal_cs>
                    <image_recording_list>
                        <image_recording image_recording_id="1">
                            <film_or_detector_model>GATAN K2 SUMMIT (4k x 4k)</film_or_detector_model>
                            <detector_mode>SUPER-RESOLUTION</detector_mode>
                            <average_electron_dose_per_image units="e/Å^2">75.0</average_electron_dose_per_image>
                        </image_recording>
                    </image_recording_list>
                </single_particle_microscopy>
            </microscopy_list>
            <singleparticle_processing image_processing_id="1">
                <image_recording_id>1</image_recording_id>
                <startup_model type_of_model="EMDB MAP"/>
                <final_reconstruction>
                    <applied_symmetry>
                        <point_group>C1</point_group>
                    </applied_symmetry>
                    <resolution units="Å" res_type="BY AUTHOR">5.5</resolution>
                    <resolution_method>FSC 0.143 CUT-OFF</resolution_method>
                    <number_images_used>616547</number_images_used>
                </final_reconstruction>
                <initial_angle_assignment>
                    <type>MAXIMUM LIKELIHOOD</type>
                </initial_angle_assignment>
                <final_angle_assignment>
                    <type>MAXIMUM LIKELIHOOD</type>
                </final_angle_assignment>
            </singleparticle_processing>
        </structure_determination>
    </structure_determination_list>
    <map format="CCP4" size_kbytes="67109">
        <file>emd_0909.map.gz</file>
        <symmetry>
            <space_group>1</space_group>
        </symmetry>
        <data_type>IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES)</data_type>
        <dimensions>
            <col>256</col>
            <row>256</row>
            <sec>256</sec>
        </dimensions>
        <origin>
            <col>0</col>
            <row>0</row>
            <sec>0</sec>
        </origin>
        <spacing>
            <x>256</x>
            <y>256</y>
            <z>256</z>
        </spacing>
        <cell>
            <a units="Å">568.832</a>
            <b units="Å">568.832</b>
            <c units="Å">568.832</c>
            <alpha units="deg">90.0</alpha>
            <beta units="deg">90.0</beta>
            <gamma units="deg">90.0</gamma>
        </cell>
        <axis_order>
            <fast>X</fast>
            <medium>Y</medium>
            <slow>Z</slow>
        </axis_order>
        <statistics>
            <minimum>-0.0906904</minimum>
            <maximum>0.15094903</maximum>
            <average>0.00006626427</average>
            <std>0.0058456706</std>
        </statistics>
        <pixel_spacing>
            <x units="Å">2.222</x>
            <y units="Å">2.222</y>
            <z units="Å">2.222</z>
        </pixel_spacing>
        <contour_list>
            <contour primary="true">
                <level>0.03</level>
                <source>AUTHOR</source>
            </contour>
        </contour_list>
        <label>::::EMDATABANK.org::::EMD-0909::::</label>
        <annotation_details>core region reconstruction</annotation_details>
    </map>
    <interpretation>
        <modelling_list>
            <modelling>
                <refinement_protocol>FLEXIBLE FIT</refinement_protocol>
                <refinement_space>REAL</refinement_space>
            </modelling>
        </modelling_list>
    </interpretation>
</emd>
