2024-11-13 REL RCSB RCSB RCSB 2018-12-06 2018-12-19 2019-08-07 2024-11-13 National Institutes of Health/National Center for Research Resources (NIH/NCRR) 5T32GM008496 United States National Science Foundation (NSF, United States) MCB-1714569 United States National Institutes of Health/National Center for Research Resources (NIH/NCRR) GM-007185 United States Howard Hughes Medical Institute (HHMI) United States Amyloid-Beta (20-34) with L-isoaspartate 23 Sawaya MR Warmack RA protofilament, 2 sub 1 screw symmetry, post-translational modification, isoaspartate, PROTEIN FIBRIL Warmack RA Boyer DR Zee CT Richards LS Sawaya MR Cascio D Gonen T Eisenberg DS Clarke SG Structure of amyloid-beta (20-34) with Alzheimer's-associated isomerization at Asp23 reveals a distinct protofilament interface. Nat Commun UK 10 3357 3357 2019 31350392 doi:10.1038/s41467-019-11183-z 2041-1723 6nb9 FULLOVERLAP crystal of amyloid-beta residues 20-34 with L-isoaspartate at position 23 crystal of amyloid-beta residues 20-34 with L-isoaspartate at position 23 0 1 6.21 Amyloid-beta A4 protein Homo sapiens 0.0014916659999999998 1 LEVO FAE(IAS)VGSNKGAIIGL P05067 water 1.8015e-05 4 HOH electronCrystallography threeDArray 2.5 7.6 water Quantifoil R1.2/1.3 COPPER 300 CARBON HOLEY ARRAY 30.0 GLOW DISCHARGE AIR ETHANE 100 FEI VITROBOT MARK IV
This sample is a crystal.
 FEI TALOS ARCTICA FLOOD BEAM DIFFRACTION FIELD EMISSION GUN 200 FEI TITAN KRIOS AUTOGRID HOLDER NITROGEN 100.0 100.0 FEI CETA (4k x 4k) 2048 2048 2 159 3.0 0.01 1050 1 DIFFRACTION PATTERN/LAYERLINES 16529 3946 82.700000000000003 0.197 0.197 28.4 0.1 0.1 1.05 1.0 1.05 315 0.1 41.200000000000003 3.09 emd_0405.map.gz 4 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 10 108 112 0 0 0 108 20 112 29.2032 4.87 32.7376 90.0 101.897 90.0 Y X Z -1.1124427 5.3232923 -0.000000001282909 0.68701303 0.2704 0.2435 0.2923 1.1 AUTHOR OTHER maximum liklihood RECIPROCAL 10.135