2018-09-19 REL PDBe PDBe PDBe 2018-06-26 2018-08-22 2018-09-12 2018-09-19 Wide Pick Filament from Pick's disease brain Falcon B Zhang W Murzin AG Murshudov G Garringer HJ Vidal R Crowther RA Ghetti B Scheres SHW Goedert M Falcon B Zhang W Murzin AG Murshudov G Garringer HJ Vidal R Crowther RA Ghetti B Scheres SHW Goedert M Structures of filaments from Pick's disease reveal a novel tau protein fold. Nature UK 561 137 140 2018 30158706 doi:10.1038/s41586-018-0454-y 1476-4687 0006 NATUAS EMD-0077 other EM volume
EMD-0077 contains the Narrow Pick Filament from the same sample
 EMD-0078 associated EM volume microtubule-associated protein tau microtubule-associated protein tau 0 1 Homo sapiens Brain Frontotemporal cortex Wide Pick Filament from Pick's disease brain LEVO KNVKSKIGSTENLKHQPGGGKVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTF helical tissue 0.5 7.4 50.0 Tris-HCl 150.0 NaCl 0.02 A8-35 Amphipol ETHANE 100 277 FEI VITROBOT MARK IV
Dispersed filaments
FEI TITAN KRIOS FLOOD BEAM BRIGHT FIELD FIELD EMISSION GUN 300 2.7 1.7 2.8 GIF Quantum LS GATAN K2 QUANTUM (4k x 4k) COUNTING 1.06 1 4.7 -0.6 C2 8.0 FSC 0.143 CUT-OFF RELION 2.1 3003 Gctf 1.06 NOT APPLICABLE emd_0078.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 180 180 180 0 0 0 180 180 180 621.0 621.0 621.0 90.0 90.0 90.0 X Y Z -0.1330608 0.51759523 -0.0033756108 0.033847462 3.45 3.45 3.45 0.17 AUTHOR emd_0078_msk_1.map emd_0078_half_map_1.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 180 180 180 0 0 0 180 180 180 621.0 621.0 621.0 90.0 90.0 90.0 X Y Z -0.051528323 0.19134523 -0.0017101305 0.015771156 3.45 3.45 3.45 0.08 AUTHOR emd_0078_half_map_2.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 180 180 180 0 0 0 180 180 180 621.0 621.0 621.0 90.0 90.0 90.0 X Y Z -0.050957825 0.19578245 -0.0016654802 0.015685247 3.45 3.45 3.45 0.08 AUTHOR