2019-03-27 OBS PDBe PDBe PDBe 2017-03-21 2017-04-19 2019-03-27 2019-03-27 Negative staining of antibodies cooperative complex formed by human IgG1 mAb1A3 and mAb1A12 bound to the N. meningitidis antigen factor H binding protein (fHbp) Peschiera I Ferlenghi I Melero R Liljeroos LJ Paccagnini E Giusti F Carazo JM Sorzano COS Scarselli M Peschiera I Giuliani M Giusti F Melero R Paccagnini E Donnarumma D Pansegrau W Carazo JM Sorzano COS Scarselli M Masignani V Liljeroos LJ Ferlenghi I Structural basis for cooperativity of human monoclonal antibodies to meningococcal factor H binding protein To Be Published 0353 EMD-3646 associated EM volume Quaternary complex formed by mAb1A3, mAb1A12 and two molecules of fHbp Quaternary complex formed by mAb1A3, mAb1A12 and two molecules of fHbp 0
Cooperative couple of human IgG1 mAbs bound to an antigen
Homo sapiens Mammalia N.meningitidis antigen factor H binding protein (fHbp) 1 Neisseria meningitidis serogroup B Escherichia coli BL21(DE3) singleParticle particle 8.0 NEGATIVE 1% Uranyl Acetate carbon/ formvar (Agar Scientific) COPPER 300 FEI/PHILIPS CM200FEG FLOOD BEAM BRIGHT FIELD FIELD EMISSION GUN 200 TVIPS TEMCAM-F224 (2k x 2k) 30.0 1 26.0 FSC 0.143 CUT-OFF 10000 OTHER PROJECTION MATCHING emd_3646.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 60 60 60 -27 -27 -27 60 60 60 396.0 396.0 396.0 90.0 90.0 90.0 X Y Z -0.097027995 0.21349856 0.00007048589 0.013146872 6.6 6.6 6.6 0.0519 AUTHOR Negative staining of cooperative couple of human IgG1 mAb1A3 and mAb1A12 bound to N.meningitidis antigen fHbp